Anna Skiada
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View article: Virulence factors are preserved within carbapenem-resistant <i>Acinetobacter baumannii</i> clades
Virulence factors are preserved within carbapenem-resistant <i>Acinetobacter baumannii</i> clades Open
Carbapenem-resistant Acinetobacter baumannii (CRAB) is an important threat to hospitalized patients. The virulence of A. baumannii varies between strains and geographic locations, which is believed to be related to its genetic plasticity. …
View article: Integration of individual preclinical and clinical anti‐infective PKPD data to predict clinical study outcomes
Integration of individual preclinical and clinical anti‐infective PKPD data to predict clinical study outcomes Open
The AIDA randomized clinical trial found no significant difference in clinical failure or survival between colistin monotherapy and colistin–meropenem combination therapy in carbapenem‐resistant Gram‐negative infections. The aim of this re…
View article: Emergomycosis, an Emerging Thermally Dimorphic Fungal Infection: A Systematic Review
Emergomycosis, an Emerging Thermally Dimorphic Fungal Infection: A Systematic Review Open
Emergomycosis is an endemic mycosis caused by the Emergomyces species. Infections due to this agent have been reported globally. Hence, the present systematic review on Emergomyces infections was conducted to study the disease epidemiology…
View article: Prevalence and Clinical Consequences of Colistin Heteroresistance and Evolution into Full Resistance in Carbapenem-Resistant Acinetobacter baumannii
Prevalence and Clinical Consequences of Colistin Heteroresistance and Evolution into Full Resistance in Carbapenem-Resistant Acinetobacter baumannii Open
To our knowledge, this is the first large-scale study to report on HR in Gram-negative bacteria. We described the prevalence of colistin HR in a large sample of carbapenem-resistant A. baumannii isolates, the evolution of many colistin HR …
View article: Epidemiology of Mucormycosis in Greece; Results from a Nationwide Prospective Survey and Published Case Reports
Epidemiology of Mucormycosis in Greece; Results from a Nationwide Prospective Survey and Published Case Reports Open
Mucormycosis has emerged as a group of severe infections mainly in immunocompromised patients. We analysed the epidemiology of mucormycosis in Greece in a multicentre, nationwide prospective survey of patients of all ages, during 2005–2022…
View article: P185 Epidemiology of human fusariosis in Greece: results from a 16-year nationwide multicenter survey
P185 Epidemiology of human fusariosis in Greece: results from a 16-year nationwide multicenter survey Open
Poster session 2, September 22, 2022, 12:30 PM - 1:30 PM Objectives Fusariosis in humans comprises a vast array of rare but serious and difficult-to-treat infections, ranging from keratitis and onychomycosis in immunocompetent hosts to lif…
View article: Global Cutaneous Mucormycosis: A Systematic Review
Global Cutaneous Mucormycosis: A Systematic Review Open
Cutaneous mucormycosis is the third most common clinical type of mucormycosis. The signs and symptoms vary widely, and it is important to make the diagnosis as early as possible in order to achieve a better outcome. We present a systematic…
View article: Connecting the Dots: Interplay of Pathogenic Mechanisms between COVID-19 Disease and Mucormycosis
Connecting the Dots: Interplay of Pathogenic Mechanisms between COVID-19 Disease and Mucormycosis Open
Coronavirus disease (COVID-19)-associated mucormycosis (CAM) is an emerging threat globally, especially in India. More than 40,000 CAM cases have been reported in India. The emergence of CAM cases in India has been attributed to environmen…
View article: Excluded versus included patients in a randomized controlled trial of infections caused by carbapenem-resistant Gram-negative bacteria: relevance to external validity
Excluded versus included patients in a randomized controlled trial of infections caused by carbapenem-resistant Gram-negative bacteria: relevance to external validity Open
Background Population external validity is the extent to which an experimental study results can be generalized from a specific sample to a defined population. In order to apply the results of a study, we should be able to assess its popul…
View article: Epidemiology and Diagnosis of Mucormycosis: An Update
Epidemiology and Diagnosis of Mucormycosis: An Update Open
Mucormycosis is an angioinvasive fungal infection, due to fungi of the order Mucorales. Its incidence cannot be measured exactly, since there are few population-based studies, but multiple studies have shown that it is increasing. The prev…
View article: Global guideline for the diagnosis and management of mucormycosis: an initiative of the European Confederation of Medical Mycology in cooperation with the Mycoses Study Group Education and Research Consortium
Global guideline for the diagnosis and management of mucormycosis: an initiative of the European Confederation of Medical Mycology in cooperation with the Mycoses Study Group Education and Research Consortium Open
Mucormycosis is a difficult to diagnose rare disease with high morbidity and mortality. Diagnosis is often delayed, and disease tends to progress rapidly. Urgent surgical and medical intervention is lifesaving. Guidance on the complex mult…
View article: Rare fungal infectious agents: a lurking enemy
Rare fungal infectious agents: a lurking enemy Open
In the expanding population of immunocompromised patients and those treated in intensive care units, rare fungal infectious agents have emerged as important pathogens, causing invasive infections associated with high morbidity and mortalit…
View article: Faculty Opinions recommendation of Talaromyces (Penicillium) marneffei infection in non-HIV-infected patients.
Faculty Opinions recommendation of Talaromyces (Penicillium) marneffei infection in non-HIV-infected patients. Open
Talaromyces (Penicillium) marneffei is an important pathogenic thermally dimorphic fungus causing systemic mycosis in Southeast Asia. The clinical significance of T. marneffei became evident when the human immunodeficiency virus (HIV)/acqu…
View article: Faculty Opinions recommendation of Scedosporiosis in a Combined Kidney and Liver Transplant Recipient: A Case Report of Possible Transmission from a Near-Drowning Donor.
Faculty Opinions recommendation of Scedosporiosis in a Combined Kidney and Liver Transplant Recipient: A Case Report of Possible Transmission from a Near-Drowning Donor. Open
Read the full review for this Faculty Opinions recommended article: Scedosporiosis in a Combined Kidney and Liver Transplant Recipient: A Case Report of Possible Transmission from a Near-Drowning Donor.
View article: Faculty Opinions recommendation of International evaluation of MIC distributions and epidemiological cutoff value (ECV) definitions for fusarium species identified by molecular methods for the CLSI broth microdilution method.
Faculty Opinions recommendation of International evaluation of MIC distributions and epidemiological cutoff value (ECV) definitions for fusarium species identified by molecular methods for the CLSI broth microdilution method. Open
The CLSI epidemiological cutoff values (ECVs) of antifungal agents are available for various Candida spp., Aspergillus spp., and the Mucorales.However, those categorical endpoints have not been established for Fusarium spp., mostly due to …
View article: Faculty Opinions recommendation of Altered Patterns of Fungal Keratitis at a London Ophthalmic Referral Hospital: An Eight-Year Retrospective Observational Study.
Faculty Opinions recommendation of Altered Patterns of Fungal Keratitis at a London Ophthalmic Referral Hospital: An Eight-Year Retrospective Observational Study. Open
PURPOSE: In previous studies of fungal keratitis (FK) from temperate countries, yeasts were the predominant isolates, with ocular surface disease (OSD) being the leading risk factor.Since the 2005-2006 outbreak of contact lens (CL)-associa…
View article: Faculty Opinions recommendation of Whole genome sequencing of emerging multidrug resistant Candida auris isolates in India demonstrates low genetic variation.
Faculty Opinions recommendation of Whole genome sequencing of emerging multidrug resistant Candida auris isolates in India demonstrates low genetic variation. Open
Candida auris is an emerging multidrug resistant yeast that causes nosocomial fungaemia and deep-seated infections.Notably, the emergence of this yeast is alarming as it exhibits resistance to azoles, amphotericin B and caspofungin, which …
View article: Faculty Opinions recommendation of Draft genome of a commonly misdiagnosed multidrug resistant pathogen Candida auris.
Faculty Opinions recommendation of Draft genome of a commonly misdiagnosed multidrug resistant pathogen Candida auris. Open
Background: Candida auris is a multidrug resistant, emerging agent of fungemia in humans.Its actual global distribution remains obscure as the current commercial methods of clinical diagnosis misidentify it as C. haemulonii.Here we report …
View article: Faculty Opinions recommendation of Development and evaluation of a real-time polymerase chain reaction assay for the rapid detection of Talaromyces marneffei MP1 gene in human plasma.
Faculty Opinions recommendation of Development and evaluation of a real-time polymerase chain reaction assay for the rapid detection of Talaromyces marneffei MP1 gene in human plasma. Open
Penicilliosis caused by Talaromyces marneffei is a common AIDS-defining illness in South and Southeast Asia.Diagnosis is based on culture which can take up to 14 days for identification, leading to treatment delay and increased mortality.W…
View article: Faculty Opinions recommendation of Matrix-assisted laser desorption ionization time-of-flight mass spectrometry for rapid identification of mold and yeast cultures of Penicillium marneffei.
Faculty Opinions recommendation of Matrix-assisted laser desorption ionization time-of-flight mass spectrometry for rapid identification of mold and yeast cultures of Penicillium marneffei. Open
Background: Penicillium marneffei is the most important thermal dimorphic fungus causing systemic mycosis in HIV-infected and other immunocompromised patients in Southeast Asia.However, laboratory diagnosis of penicilliosis, which relies o…
View article: Faculty Opinions recommendation of Genomics and Comparative Genomic Analyses Provide Insight into the Taxonomy and Pathogenic Potential of Novel Emmonsia Pathogens.
Faculty Opinions recommendation of Genomics and Comparative Genomic Analyses Provide Insight into the Taxonomy and Pathogenic Potential of Novel Emmonsia Pathogens. Open
Over the last 50 years, newly described species of Emmonsia-like fungi have been implicated globally as sources of systemic human mycosis (emmonsiosis). Their ability to convert into yeast-like cells capable of replication and extra-pulmon…
View article: Faculty Opinions recommendation of Multidrug-Resistant Candida haemulonii and C. auris, Tel Aviv, Israel.
Faculty Opinions recommendation of Multidrug-Resistant Candida haemulonii and C. auris, Tel Aviv, Israel. Open
Candida auris and C. haemulonii are closely related, multidrug-resistant emerging fungal pathogens that are not readily distinguishable with phenotypic assays.We studied C. auris and C. haemulonii clinical isolates from 2 hospitals in cent…
View article: Faculty Opinions recommendation of 50 years of emmonsia disease in humans: the dramatic emergence of a cluster of novel fungal pathogens.
Faculty Opinions recommendation of 50 years of emmonsia disease in humans: the dramatic emergence of a cluster of novel fungal pathogens. Open
No abstract available PMID: 26584311
View article: Challenges in the diagnosis and treatment of mucormycosis
Challenges in the diagnosis and treatment of mucormycosis Open
The diagnosis and treatment of mucormycosis are challenging. The incidence of the disease seems to be increasing. Hematological malignancies are the most common underlying disease in countries with high income and uncontrolled diabetes in …
View article: ECIL-6 guidelines for the treatment of invasive candidiasis, aspergillosis and mucormycosis in leukemia and hematopoietic stem cell transplant patients
ECIL-6 guidelines for the treatment of invasive candidiasis, aspergillosis and mucormycosis in leukemia and hematopoietic stem cell transplant patients Open
The European Conference on Infections in Leukemia (ECIL) provides recommendations for diagnostic strategies and prophylactic, pre-emptive or targeted therapy strategies for various types of infection in patients with hematologic malignanci…