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Dysregulated Humoral and Cellular Response to Sars-Cov-2 Vaccination in Patients with MGUS and SMM Open

Yoshinobu Konishi, Romanos Sklavenitis‐Pistofidis, Michelle P. Aranha, Ting Wu, Hong Yue , et al. · 2022

Introduction Patients with hematological malignancies, including multiple myeloma (MM), experience sub-optimal responses to SARS-CoV-2 vaccination. Monoclonal Gammopathy of Undetermined Significance (MGUS) and Smoldering Multiple Myeloma (…

Attenuated response to SARS-CoV-2 vaccine in patients with asymptomatic precursor stages of multiple myeloma and Waldenstrom macroglobulinemia Open

Yoshinobu Konishi, Romanos Sklavenitis‐Pistofidis, Hong Yue, Federico Ferrari, Robert Redd , et al. · 2021

Identification of ESRE regulatory molecules Open

Anna V. Justis · 2021

The ethanol and stress response element (ESRE) network in Caenorhabditis elegans regulates stress-induced gene expression. The ESRE network is highly conserved and is involved in responding to a variety of environmental stresses. The ESRE …

Coxiella burnetii Blocks Intracellular Interleukin-17 Signaling in Macrophages Open

Tatiana M. Clemente, Minal Mulye, Anna V. Justis, Srinivas Nallandhighal, Tuan M. Tran , et al. · 2018

Coxiella burnetii is an obligate intracellular bacterium and the etiological agent of Q fever. Successful host cell infection requires the Coxiella type IVB secretion system (T4BSS), which translocates bacterial effector proteins across th…

Coxiella burnetiiblocks intracellular IL-17 signaling in macrophages Open

Tatiana M. Clemente, Minal Mulye, Anna V. Justis, Srinivas Nallandhighal, Tuan M. Tran , et al. · 2018

Coxiella burnetii is an obligate intracellular bacterium and the etiological agent of Q fever. Successful host cell infection requires the Coxiella Type IVB Secretion System (T4BSS), which translocates bacterial effector proteins across th…

Recruitment and function of ORP1L on the Coxiella burnetii parasitophorous vacuole Open

Anna V. Justis · 2018

Manipulation of Host Cholesterol by Obligate Intracellular Bacteria Open

Dhritiman Samanta, Minal Mulye, Tatiana M. Clemente, Anna V. Justis, Stacey D. Gilk · 2017

Cholesterol is a multifunctional lipid that plays important metabolic and structural roles in the eukaryotic cell. Despite having diverse lifestyles, the obligate intracellular bacterial pathogens Chlamydia, Coxiella, Anaplasma, Ehrlich…

View article: Interactions between theCoxiella burnetiiparasitophorous vacuole and the endoplasmic reticulum involve the host protein ORP1L

Interactions between theCoxiella burnetiiparasitophorous vacuole and the endoplasmic reticulum involve the host protein ORP1L Open

Anna V. Justis, Bryan Hansen, Paul A. Beare, Kourtney B. King, Robert A. Heinzen , et al. · 2016

Coxiella burnetii is a gram-negative intracellular bacterium that forms a large, lysosome-like parasitophorous vacuole (PV) essential for bacterial replication. Host membrane lipids are critical for the formation and maintenance of this in…