Anna W. Daszkowski
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View article: A history of ethanol drinking increases locomotor stimulation and blunts enhancement of dendritic dopamine transmission by methamphetamine
A history of ethanol drinking increases locomotor stimulation and blunts enhancement of dendritic dopamine transmission by methamphetamine Open
Ethanol and psychostimulant use disorders exhibit comorbidity in humans and cross‐sensitization in animal models, but the neurobiological underpinnings of this are not well understood. Ethanol acutely increases dopamine neuron excitability…
View article: An intersubunit electrostatic interaction in the GABAA receptor facilitates its responses to benzodiazepines
An intersubunit electrostatic interaction in the GABAA receptor facilitates its responses to benzodiazepines Open
Benzodiazepines are positive allosteric modulators of the GABAA receptor (GABAAR), acting at the α-γ subunit interface to enhance GABAAR function. GABA or benzodiazepine binding induces distinct conformational changes in the GABAAR. The mo…