Anna Zhao
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View article: Frog-Derived Peptide RL-RF10 Facilitates Gingival Repair and Regeneration Through the Integrin αvβ3/p38/Snail1 Axis
Frog-Derived Peptide RL-RF10 Facilitates Gingival Repair and Regeneration Through the Integrin αvβ3/p38/Snail1 Axis Open
RL-RF10 is the first known amphibian-derived peptide with potential for gingival repair and regeneration. It promotes cell migration, a process linked to p38 mitogen-activated protein kinases pathway activation and associated with the upre…
View article: Tattoos as a risk factor for malignant lymphoma
Tattoos as a risk factor for malignant lymphoma Open
A clinical decision report using Nielsen C, Jerkeman M, Jöud AS. Tattoos as a risk factor for malignant lymphoma: a population-based case-control study. EClinicalMedicine. 2024;72:102649. Published 2024 May 21. https://doi.org/10.1016/j.ec…
View article: Development of a machine learning-based predictive model for maxillary sinus cysts and exploration of clustering patterns
Development of a machine learning-based predictive model for maxillary sinus cysts and exploration of clustering patterns Open
These findings provide valuable insights into the etiology and risk stratification of maxillary sinus cysts, offering a theoretical basis for their prevention and clinical management. The integration of CBCT imaging and ML techniques holds…
View article: Exploring the risk factors and clustering patterns of periodontitis in patients with different subtypes of diabetes through machine learning and cluster analysis
Exploring the risk factors and clustering patterns of periodontitis in patients with different subtypes of diabetes through machine learning and cluster analysis Open
Aim: To analyse the risk factors contributing to the prevalence of periodontitis among clusters of patients with diabetes and to examine the clustering patterns of clinical blood biochemical indicators. Materials and methods: Data regardin…
View article: Role of fatty acid metabolism-related genes in periodontitis based on machine learning and bioinformatics analysis.
Role of fatty acid metabolism-related genes in periodontitis based on machine learning and bioinformatics analysis. Open
This study provides new insights and ideas for the occurrence and development mechanism of periodontitis and proposes a diagnostic model based on hub DEFAMRGs to provide new directions for diagnosis and treatment.
View article: Construction of a diagnostic model based on random forest and artificial neural network for peri-implantitis.
Construction of a diagnostic model based on random forest and artificial neural network for peri-implantitis. Open
The diagnostic model of peri-implantitis constructed by RF and ANN has high confidence, and CD38, CYBB, FCGR2A, SELL, TLR4, and CXCL8 are potential diagnostic markers. FOXC1, GATA2, and NF-κB1 may be essential transcription factors in peri…
View article: The application of two drainage angles in neurocritical care patients with complicated pneumonia: a randomized controlled trial
The application of two drainage angles in neurocritical care patients with complicated pneumonia: a randomized controlled trial Open
Background Although head elevation is an early first-line treatment for elevated intracranial pressure (ICP), the use of the head-down or prone position in managing neurocritical patients is controversial because a change in a position dir…
View article: The influence of anti-involution training on the critical thinking of young healthcare professionals in dental outpatient clinics-based on machine learning model
The influence of anti-involution training on the critical thinking of young healthcare professionals in dental outpatient clinics-based on machine learning model Open
Background The relationship between the impact of anti-involution training on critical thinking and its propensity indicators among young healthcare professionals in dental outpatient clinics remains to be determined. Therefore, this study…
View article: Mechanism of crocin I on ANIT-induced intrahepatic cholestasis by combined metabolomics and transcriptomics
Mechanism of crocin I on ANIT-induced intrahepatic cholestasis by combined metabolomics and transcriptomics Open
Background: Intrahepatic cholestasis (IC) is a disorder of bile production, secretion, and excretion with various causes. Crocin I (CR) is effective in the treatment of IC, but its underlying mechanisms need to be further explored. We aime…
View article: Cerebral endothelial cell derived small extracellular vesicles improve cognitive function in aged diabetic rats
Cerebral endothelial cell derived small extracellular vesicles improve cognitive function in aged diabetic rats Open
Small extracellular vesicles (sEVs) mediate cell-cell communication by transferring their cargo biological materials into recipient cells. Diabetes mellitus (DM) induces cerebral vascular dysfunction and neurogenesis impairment, which are …
View article: A Non-iterative Overlapping Schwarz Waveform Relaxation Algorithm for Wave Equation
A Non-iterative Overlapping Schwarz Waveform Relaxation Algorithm for Wave Equation Open
The Schwarz Waveform Relaxation algorithm (SWR) exchanges the waveform of boundary value between neighbouring sub-domains, which provides a more efficient way than the other Schwarz algorithms to realize distributed computation. However, t…
View article: Utilization of a Pediatric Ethics Committee by Certified Child Life Specialists: Barriers and Opportunities
Utilization of a Pediatric Ethics Committee by Certified Child Life Specialists: Barriers and Opportunities Open
Objective: The aims of this study are to understand the perspectives and experiences of CCLSs within the Pediatrics Ethics Committee and to explore the role of CCLSs in requesting ethics consults. Method: The study was conducted at Yale Ne…
View article: Implementation of Patient Screening in Ambulatory Settings During the COVID-19 Pandemic
Implementation of Patient Screening in Ambulatory Settings During the COVID-19 Pandemic Open
Pashankar, Dinesh S. MD, MBA; Follo, Marie; Zhao, Anna M. BA; Saeri, Maryam MBA; Khokhar, Babar MD, MBA Author Information
View article: Medical Student Patient Outreach to Ensure Continuity of Care During the COVID-19 Pandemic
Medical Student Patient Outreach to Ensure Continuity of Care During the COVID-19 Pandemic Open
By calling patients whose appointments had been canceled during a rapid transition to telemedicine, the MSTF helped bridge a potential gap in care by offering patients communication with their care teams, information, and support. We propo…
View article: A Quality Improvement Project to Improve First Case On-time Starts in the Pediatric Operating Room
A Quality Improvement Project to Improve First Case On-time Starts in the Pediatric Operating Room Open
Background: Delays in the operating room (OR) can lead to increased hospital costs as well as patient and provider dissatisfaction. Starting the first case on time in the OR can potentially prevent subsequent delays. We designed a quality …
View article: Long noncoding RNA mediates stroke-induced neurogenesis
Long noncoding RNA mediates stroke-induced neurogenesis Open
Neurogenesis contributes to poststroke recovery. Long noncoding RNAs (lncRNAs) participate in the regulation of stem cell self-renewal and differentiation. However, the role of lncRNAs in stroke-induced neurogenesis remains unknown. In thi…
View article: Renal stone composed of ritonavir
Renal stone composed of ritonavir Open
Nephrolithiasis is a well-known side effect of many HIV protease inhibitors. However, there have not been reports of stones associated with ritonavir use. Here, we report the case of a 33-year-old woman with HIV on antiretroviral therapy w…
View article: Ring finger protein 31–mediated atypical ubiquitination stabilizes forkhead box P3 and thereby stimulates regulatory T-cell function
Ring finger protein 31–mediated atypical ubiquitination stabilizes forkhead box P3 and thereby stimulates regulatory T-cell function Open
The CD4+CD25+FOXP3+ regulatory T (Treg) cells are critical for maintaining immune tolerance in healthy individuals and are reported to restrict anti-inflammatory responses and thereby promote tumor progression, suggesting them as a target …