Annabel Webb
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View article: Concurrent Validity and Inter-Rater Reliability of the Motor Optimality Score-Revised in a Neonatal Surgical Population
Concurrent Validity and Inter-Rater Reliability of the Motor Optimality Score-Revised in a Neonatal Surgical Population Open
Objectives: This study aims to evaluate the concurrent validity and inter-rater reliability and agreement of the Motor Optimality Score-Revised (MOS-R) in infants following major surgery in the neonatal period. Methods: A cross-sectional s…
View article: Combining Abdominal Ultrasound and Radiography for Surgical Risk Prediction in Necrotising Enterocolitis: A Prospective Cohort Study
Combining Abdominal Ultrasound and Radiography for Surgical Risk Prediction in Necrotising Enterocolitis: A Prospective Cohort Study Open
Objective To evaluate whether combining abdominal ultrasound with radiography improves diagnostic accuracy and surgical risk prediction in neonates with suspected necrotising enterocolitis (NEC) compared with radiography alone. Design, set…
View article: Early detection of cerebral palsy among a high-risk cohort in Bangladesh
Early detection of cerebral palsy among a high-risk cohort in Bangladesh Open
Objective To evaluate the predictive validity of best practice early detection tools for cerebral palsy (CP) in a high-risk cohort. Study design Prospective longitudinal cohort study. Setting Neonatal intensive care unit of a regional tert…
View article: Educating antenatal patients about cytomegalovirus infection: An e-learning package improves general practitioners’ knowledge and intention to implement clinical guidelines
Educating antenatal patients about cytomegalovirus infection: An e-learning package improves general practitioners’ knowledge and intention to implement clinical guidelines Open
Targeted e-learning can improve GP knowledge and confidence, and can support the implementation of the national congenital CMV risk-reduction guidelines.
View article: Clinical Evidence of Mesenchymal Stromal Cells for Cerebral Palsy: Scoping Review with Meta-Analysis of Efficacy in Gross Motor Outcomes
Clinical Evidence of Mesenchymal Stromal Cells for Cerebral Palsy: Scoping Review with Meta-Analysis of Efficacy in Gross Motor Outcomes Open
Mesenchymal stromal cells (MSCs) have been under clinical investigation for the treatment of cerebral palsy (CP) for over a decade. However, the field has been limited by study heterogeneity and variable reports of efficacy. We conducted a…
View article: Combined Language and Code Emergent Literacy Intervention for At‐Risk Preschool Children: A Systematic Meta‐Analytic Review
Combined Language and Code Emergent Literacy Intervention for At‐Risk Preschool Children: A Systematic Meta‐Analytic Review Open
This meta‐analytic review explored the characteristics and effectiveness of combined language (e.g., vocabulary) and code (e.g., phonological awareness) interventions, including synergistic intervention effects for at‐risk preschoolers. Da…
View article: Cord Blood Treatment for Children With Cerebral Palsy: Individual Participant Data Meta-Analysis
Cord Blood Treatment for Children With Cerebral Palsy: Individual Participant Data Meta-Analysis Open
CONTEXT Umbilical cord blood (UCB) is a novel treatment for cerebral palsy (CP), with trials indicating UCB can improve gross motor function. However, heterogeneity has limited the ability to interpret findings. OBJECTIVE Assess the safety…
View article: A 2‐Min Cytomegalovirus (<scp>CMV</scp>) Awareness Video Improves Pregnant Women's Knowledge and Planned Adherence to Hygiene Precautions
A 2‐Min Cytomegalovirus (<span>CMV</span>) Awareness Video Improves Pregnant Women's Knowledge and Planned Adherence to Hygiene Precautions Open
Introduction Congenital cytomegalovirus (cCMV) is a leading infectious cause of life‐long neurodevelopmental disabilities, but public awareness of CMV is low. This study evaluated a short educational video on cCMV for its acceptability and…
View article: Using Social Network Analysis to Understand the Effect of Developmental Care Education
Using Social Network Analysis to Understand the Effect of Developmental Care Education Open
View article: On a penalised likelihood approach for joint modelling of longitudinal covariates and partly interval-censored data -- an application to the Anti-PD1 brain collaboration trial
On a penalised likelihood approach for joint modelling of longitudinal covariates and partly interval-censored data -- an application to the Anti-PD1 brain collaboration trial Open
This article considers the joint modeling of longitudinal covariates and partly-interval censored time-to-event data. Longitudinal time-varying covariates play a crucial role in obtaining accurate clinically relevant predictions using a su…
View article: Cerebral palsy in Australia: birth prevalence, 1995–2016, and differences by residential remoteness: a population‐based register study
Cerebral palsy in Australia: birth prevalence, 1995–2016, and differences by residential remoteness: a population‐based register study Open
Objective To examine recent changes in the birth prevalence of cerebral palsy in Australia; to examine the functional mobility of children with cerebral palsy by residential remoteness. Study design Population‐based register study; analysi…
View article: Continuous local anaesthetic wound infusion in infants undergoing thoracic or abdominal surgery: A systematic review
Continuous local anaesthetic wound infusion in infants undergoing thoracic or abdominal surgery: A systematic review Open
Objective: To determine whether continuous local anaesthetic wound infusion (CLAWI) provides more effective pain relief and decrease the need for systemic opioids compared to other analgesic agents in term or preterm newborn infants underg…
View article: Clinical characteristics and outcomes of perinatal stroke in Australia: Population‐based longitudinal study
Clinical characteristics and outcomes of perinatal stroke in Australia: Population‐based longitudinal study Open
Aim Perinatal stroke is one of the main causes of hemiplegia and seizure disorder. This study aimed to analyse the clinical characteristics and outcomes of perinatal stroke in a cohort of Australian children for its early detection. Method…
View article: Answering the call: co-designing a global trials network for cerebral palsy
Answering the call: co-designing a global trials network for cerebral palsy Open
View article: Clinician Perceptions of Family-Centered Care in Pediatric and Congenital Heart Settings
Clinician Perceptions of Family-Centered Care in Pediatric and Congenital Heart Settings Open
Importance Family-centered care recognizes families as central to child health and well-being and prioritizes clinician collaboration with families to ensure optimal pediatric care and outcomes. Clinician interpersonal sensitivity and comm…
View article: The critical need to accelerate cerebral palsy research with consumer engagement, global networks, and adaptive designs
The critical need to accelerate cerebral palsy research with consumer engagement, global networks, and adaptive designs Open
The prevalence of cerebral palsy (CP) varies globally, with higher rates and burden of disease in low- and middle-income countries. CP is a lifelong condition with no cure, presenting diverse challenges such as motor impairment, epilepsy, …
View article: A comparison of ductal stenting and surgical shunts for infants with duct-dependent pulmonary blood flow; the impact of single versus biventricular repair pathways on outcomes.
A comparison of ductal stenting and surgical shunts for infants with duct-dependent pulmonary blood flow; the impact of single versus biventricular repair pathways on outcomes. Open
Background: Ductal stenting (DS) is an alternative to the Blalock-Taussig-Thomas Shunt (BTTS) as initial palliation for congenital heart disease with duct dependent pulmonary blood flow (DDBPF). We sought to analyse the impact of intended …
View article: CP Global Clinical Trials Network, an International Trials Network for Cerebral Palsy: Global Prioritisation Process Using the Modified Delphi Method
CP Global Clinical Trials Network, an International Trials Network for Cerebral Palsy: Global Prioritisation Process Using the Modified Delphi Method Open
View article: Evaluation of a Modified Mindfulness-Based Stress Reduction Intervention for Adults with Cerebral Palsy and Anxiety and/or Emotion Regulation Difficulties—A Randomised Control Trial
Evaluation of a Modified Mindfulness-Based Stress Reduction Intervention for Adults with Cerebral Palsy and Anxiety and/or Emotion Regulation Difficulties—A Randomised Control Trial Open
Mindfulness-Based Stress Reduction (MBSR) has not yet been evaluated for people with cerebral palsy (CP). The aims of this randomised control trial were to investigate whether a modified telehealth MBSR program could improve mindfulness an…
View article: Abstract 5 Umbilical Cord Blood Treatment to Improve Gross Motor Function in Individuals with Cerebral Palsy: Results from an Individual Participant Data Meta-Analysis
Abstract 5 Umbilical Cord Blood Treatment to Improve Gross Motor Function in Individuals with Cerebral Palsy: Results from an Individual Participant Data Meta-Analysis Open
Introduction Umbilical cord blood (UCB) is a novel treatment for cerebral palsy (CP) with clinical trials indicating UCB is safe and can improve gross motor function. However, heterogeneity across research design, participant selection and…
View article: Out-of-pocket costs for families and people living with cerebral palsy in Australia
Out-of-pocket costs for families and people living with cerebral palsy in Australia Open
The most recent cost estimates of cerebral palsy (CP) in Australia did not include out-of-pocket costs for families. This study aimed to: 1) describe and estimate out-of-pocket costs for people with CP and their families by age and gross m…
View article: Risk factors for perinatal stroke in term infants: A case–control study in Australia
Risk factors for perinatal stroke in term infants: A case–control study in Australia Open
Aim The aetiology of perinatal stroke is poorly understood. This study aimed to prospectively confirm the risk factors and identify any previously unknown variables. Methods A prospective case–control study was conducted in Australia. Univ…
View article: Acceptability of neural stem cell therapy for cerebral palsy: survey of the Australian cerebral palsy community
Acceptability of neural stem cell therapy for cerebral palsy: survey of the Australian cerebral palsy community Open
View article: Prevalence & Risk Factors for Perinatal Stroke: A Population-Based Study
Prevalence & Risk Factors for Perinatal Stroke: A Population-Based Study Open
Objectives The study objective was to calculate the birth prevalence of perinatal stroke and examine risk factors in term infants. Some risk factors are present in healthy infants, making it difficult to determine at-risk infants. Study De…
View article: Cox models with time‐varying covariates and partly‐interval censoring–A maximum penalised likelihood approach
Cox models with time‐varying covariates and partly‐interval censoring–A maximum penalised likelihood approach Open
Time‐varying covariates can be important predictors when model based predictions are considered. A Cox model that includes time‐varying covariates is usually referred to as an extended Cox model. When only right censoring is presented in t…
View article: Can web-based implementation interventions improve physician early diagnosis of cerebral palsy? Protocol for a 3-arm parallel superiority randomised controlled trial and cost–consequence analysis comparing adaptive and non-adaptive virtual patient instructional designs with control to evaluate effectiveness on physician behaviour, diagnostic skills and patient outcomes
Can web-based implementation interventions improve physician early diagnosis of cerebral palsy? Protocol for a 3-arm parallel superiority randomised controlled trial and cost–consequence analysis comparing adaptive and non-adaptive virtual patient instructional designs with control to evaluate effectiveness on physician behaviour, diagnostic skills and patient outcomes Open
Introduction Cerebral palsy (CP) is the most common childhood physical disability. Accurate diagnosis before 6 months is possible using predictive tools and decision-making skills. Yet diagnosis is typically made at 12–24 months of age, hi…
View article: A validation and acceptability study of cognitive testing using switch and eye-gaze control technologies for children with motor and speech impairments: A protocol paper
A validation and acceptability study of cognitive testing using switch and eye-gaze control technologies for children with motor and speech impairments: A protocol paper Open
Despite the importance of knowing the cognitive capabilities of children with neurodevelopmental conditions, less than one-third of children with cerebral palsy participate in standardized assessments. Globally, approximately 50% of people…
View article: Global prevalence of cerebral palsy: A systematic analysis
Global prevalence of cerebral palsy: A systematic analysis Open
Aim To determine trends and current estimates in regional and global prevalence of cerebral palsy (CP). Method A systematic analysis of data from participating CP registers/surveillance systems and population‐based prevalence studies (from…
View article: Acceptability of neural stem cell therapy for cerebral palsy: survey of the Australian cerebral palsy community
Acceptability of neural stem cell therapy for cerebral palsy: survey of the Australian cerebral palsy community Open
Background: Neural stem cells (NSCs) have the potential to engraft and replace damaged brain tissue, repairing the damaged neonatal brain that causes cerebral palsy (CP). There are procedures that could increase engraftment of NSCs and may…
View article: Continuous local anaesthetic wound infusion of bupivacaine for postoperative analgesia in neonates: a randomised control trial (CANWIN Study)
Continuous local anaesthetic wound infusion of bupivacaine for postoperative analgesia in neonates: a randomised control trial (CANWIN Study) Open
Objective To determine the effect of continuous wound infusion of local anaesthetic drug (bupivacaine) on total amount of systemic opioid use in the first 72 hours in newborn infants undergoing laparotomy. Design A two-arm parallel, open-l…