Annabelle Jin
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View article: A spatiotemporal cell atlas of cardiopulmonary progenitor cell allocation during development
A spatiotemporal cell atlas of cardiopulmonary progenitor cell allocation during development Open
The heart and lung co-orchestrate their development during organogenesis. The mesoderm surrounding both the developing heart and anterior foregut endoderm provides instructive cues guiding cardiopulmonary development. Additionally, it serv…
View article: A Spatiotemporal Cell Atlas of Cardiopulmonary Progenitor Cell Allocation During Development
A Spatiotemporal Cell Atlas of Cardiopulmonary Progenitor Cell Allocation During Development Open
View article: Endodermal BRD4 mediates epithelial-mesenchymal crosstalk during lung development
Endodermal BRD4 mediates epithelial-mesenchymal crosstalk during lung development Open
SUMMARY Lung morphogenesis relies on diverse cell intrinsic and extrinsic mechanisms to ensure proper cellular differentiation and compartmentalization. Using genetic mouse models, tissue explants, and transcriptomic analysis, we demonstra…
View article: CXCL12 defines lung endothelial heterogeneity and promotes distal vascular growth
CXCL12 defines lung endothelial heterogeneity and promotes distal vascular growth Open
There is a growing amount of data uncovering the cellular diversity of the pulmonary circulation and mechanisms governing vascular repair after injury. However, the molecular and cellular mechanisms contributing to the morphogenesis and gr…