Anne Couturier‐Tarrade
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View article: Sex-specific differences in the influence of maternal obesity on the oxidative and inflammatory status in the maternal-placental-fetal unit: new insights into the placental sphingolipid profile
Sex-specific differences in the influence of maternal obesity on the oxidative and inflammatory status in the maternal-placental-fetal unit: new insights into the placental sphingolipid profile Open
View article: PFAS exposure during pregnancy: Implications for placental health and functioning
PFAS exposure during pregnancy: Implications for placental health and functioning Open
View article: Sex-Specific Differences in the Influence of Maternal Obesity on the Oxidative and Inflammatory Status in the Maternal-Placental-Fetal Unit: New Insights into the Placental Sphingolipid Profile
Sex-Specific Differences in the Influence of Maternal Obesity on the Oxidative and Inflammatory Status in the Maternal-Placental-Fetal Unit: New Insights into the Placental Sphingolipid Profile Open
View article: Systèmes ovins innovants en Ile de France : Evaluation de la contamination des brebis et de leurs fourrages par des micro-polluants et profilage en acides gras des fluides animauxdes produits animaux
Systèmes ovins innovants en Ile de France : Evaluation de la contamination des brebis et de leurs fourrages par des micro-polluants et profilage en acides gras des fluides animauxdes produits animaux Open
International audience
View article: Short-Half-Life Chemicals: Maternal Exposure and Offspring Health Consequences—The Case of Synthetic Phenols, Parabens, and Phthalates
Short-Half-Life Chemicals: Maternal Exposure and Offspring Health Consequences—The Case of Synthetic Phenols, Parabens, and Phthalates Open
Phenols, parabens, and phthalates (PPPs) are suspected or known endocrine disruptors. They are used in consumer products that pregnant women and their progeny are exposed to daily through the placenta, which could affect offspring health. …
View article: Preconception and/or preimplantation exposure to a mixture of environmental contaminants altered fetoplacental development and placental function in a rabbit model
Preconception and/or preimplantation exposure to a mixture of environmental contaminants altered fetoplacental development and placental function in a rabbit model Open
Pregnant women are daily exposed to environmental contaminants, including endocrine disruptors that can impact the offspring's health. This study aimed to evaluate the effects of maternal oral exposure to a mixture of contaminants at a dos…
View article: Is the rabbit a natural model of fetal growth restriction? Morphological and functional characterization study using diffusion-weighted MRI and stereology
Is the rabbit a natural model of fetal growth restriction? Morphological and functional characterization study using diffusion-weighted MRI and stereology Open
View article: Pulmonary maternal immune activation does not cross the placenta but leads to fetal metabolic adaptation
Pulmonary maternal immune activation does not cross the placenta but leads to fetal metabolic adaptation Open
View article: Associations between synthetic phenols, phthalates, and placental growth/function: a longitudinal cohort with exposure assessment in early pregnancy
Associations between synthetic phenols, phthalates, and placental growth/function: a longitudinal cohort with exposure assessment in early pregnancy Open
STUDY QUESTION Is exposure to environmental chemicals associated with modifications of placental morphology and function? SUMMARY ANSWER Phthalates, a class of ubiquitous chemicals, showed an association with altered placental weight, plac…
View article: Obesity during Pregnancy in the Horse: Effect on Term Placental Structure and Gene Expression, as Well as Colostrum and Milk Fatty Acid Concentration
Obesity during Pregnancy in the Horse: Effect on Term Placental Structure and Gene Expression, as Well as Colostrum and Milk Fatty Acid Concentration Open
In horses, the prevalence of obesity is high and associated with serious metabolic pathologies. Being a broodmare has been identified as a risk factor for obesity. In other species, maternal obesity is known to affect the development of th…
View article: Intra‐uterine programming of future fertility
Intra‐uterine programming of future fertility Open
The developmental origins of health and disease (DOHaD) shows that a relationship exists between parental environment at large, foeto‐placental development and the risk for the offspring to develop non‐transmittable disease(s) in adulthood…
View article: The Effect of Maternal Exposure to a Diet High in Fats and Cholesterol on the Placental Function and Phenotype of the Offspring in a Rabbit Model: A Summary Review of About 15 Years of Research
The Effect of Maternal Exposure to a Diet High in Fats and Cholesterol on the Placental Function and Phenotype of the Offspring in a Rabbit Model: A Summary Review of About 15 Years of Research Open
The rates of obesity and being overweight are increasing all around the world, especially among women of childbearing age, in part due to overconsumption of lipids. The aim of this summary review was to present the cellular and molecular e…
View article: Placental-fetal distribution of carbon particles in a pregnant rabbit model after repeated exposure to diluted diesel engine exhaust
Placental-fetal distribution of carbon particles in a pregnant rabbit model after repeated exposure to diluted diesel engine exhaust Open
View article: Multigenerational Effects of a Complex Human-Relevant Exposure during Folliculogenesis and Preimplantation Embryo Development: The FEDEXPO Study
Multigenerational Effects of a Complex Human-Relevant Exposure during Folliculogenesis and Preimplantation Embryo Development: The FEDEXPO Study Open
Animal toxicological studies often fail to mimic the complexity of the human exposome, associating low doses, combined molecules and long-term exposure. Since the reproductive potential of a woman begins in the fetal ovary, the literature …
View article: Pulmonary maternal immune activation does not extend through the placenta but leads to fetal metabolic adaptation
Pulmonary maternal immune activation does not extend through the placenta but leads to fetal metabolic adaptation Open
Maternal immune system activation (MIA) during pregnancy can disrupt the fetal environment, causing postnatal susceptibility to disorders. How the placenta and the fetus respond to acute MIA over time is unknown. Here, we characterized the…
View article: Associations between phenols and phthalates and placental weight in a mother-child cohort with improved exposure assessment
Associations between phenols and phthalates and placental weight in a mother-child cohort with improved exposure assessment Open
Background and Aim: The placenta plays a key role in assuring a normal foetal development and growth. Few epidemiological studies have investigated the effects of phenols and phthalates on placental function. We aimed to explore whether ma…
View article: Importance of Windows of Exposure to Maternal High-Fat Diet and Feto-Placental Effects: Discrimination Between Pre-conception and Gestational Periods in a Rabbit Model
Importance of Windows of Exposure to Maternal High-Fat Diet and Feto-Placental Effects: Discrimination Between Pre-conception and Gestational Periods in a Rabbit Model Open
Context and Aim: Lipid overnutrition in female rabbits, from prepuberty, leads to impaired metabolism (dyslipidemia and increased adiposity) and follicular atresia, and, when continued during gestation, affects offspring phenotype with int…
View article: Prenatal air pollution exposure to diesel exhaust induces cardiometabolic disorders in adulthood in a sex-specific manner
Prenatal air pollution exposure to diesel exhaust induces cardiometabolic disorders in adulthood in a sex-specific manner Open
In utero exposure to air pollution predisposed rabbit offspring to cardiometabolic disorders in a sex-specific manner.
View article: Analysis of blood parameters and molecular endometrial markers during early reperfusion in two ovine models of uterus transplantation
Analysis of blood parameters and molecular endometrial markers during early reperfusion in two ovine models of uterus transplantation Open
The dissection of the veins is the trickiest step of Uterine transplantation (UTx). Performing the anastomosis of a single uterine vein could bring a therapeutic benefit and simplification of surgery and serve for managing unilateral venou…
View article: Pressurized intra-peritoneal aerosol chemotherapy (PIPAC): increased intraperitoneal pressure does not affect distribution patterns but leads to deeper penetration depth of doxorubicin in a sheep model
Pressurized intra-peritoneal aerosol chemotherapy (PIPAC): increased intraperitoneal pressure does not affect distribution patterns but leads to deeper penetration depth of doxorubicin in a sheep model Open
View article: Progress and challenges in developing organoids in farm animal species for the study of reproduction and their applications to reproductive biotechnologies
Progress and challenges in developing organoids in farm animal species for the study of reproduction and their applications to reproductive biotechnologies Open
View article: Pressurized Intra-Peritoneal Aerosol Chemotherapy (PIPAC): increased intraperitoneal pressure does not affect distribution patterns but leads to deeper penetration depth of doxorubicin in a sheep model
Pressurized Intra-Peritoneal Aerosol Chemotherapy (PIPAC): increased intraperitoneal pressure does not affect distribution patterns but leads to deeper penetration depth of doxorubicin in a sheep model Open
Background Pressurized Intra-Peritoneal Aerosol Chemotherapy (PIPAC) is an innovative treatment against peritoneal carcinomatosis. Doxorubicin is a common intra-venous chemotherapy used for peritoneal carcinomatosis and for PIPAC. This stu…
View article: Maternal Obesity Influences Placental Nutrient Transport, Inflammatory Status, and Morphology in Human Term Placenta
Maternal Obesity Influences Placental Nutrient Transport, Inflammatory Status, and Morphology in Human Term Placenta Open
Context Maternal obesity has a significant impact on placental development. However, this impact on the placenta’s structure and function (ie, nutrient transport and hormone and cytokine production) is a controversial subject. Objective We…
View article: Preserved efficiency of sickle cell disease placentas despite altered morphology and function
Preserved efficiency of sickle cell disease placentas despite altered morphology and function Open
View article: Pressurized Intra-Peritoneal Aerosol Chemotherapy (PIPAC): Does increased intraperitoneal pressure change distribution patterns and penetration depth of doxorubicin in a sheep model?
Pressurized Intra-Peritoneal Aerosol Chemotherapy (PIPAC): Does increased intraperitoneal pressure change distribution patterns and penetration depth of doxorubicin in a sheep model? Open
Background:Pressurized Intra-Peritoneal Aerosol Chemotherapy (PIPAC) is an innovative treatment against peritoneal carcinomatosis. Doxorubicin is a common intra-venous chemotherapy used for peritoneal carcinomatosis and for PIPAC. This stu…
View article: Deciphering the Impact of Early-Life Exposures to Highly Variable Environmental Factors on Foetal and Child Health: Design of SEPAGES Couple-Child Cohort
Deciphering the Impact of Early-Life Exposures to Highly Variable Environmental Factors on Foetal and Child Health: Design of SEPAGES Couple-Child Cohort Open
In humans, studies based on Developmental Origins of Health and Disease (DOHaD) concept and targeting short half-lived chemicals, including many endocrine disruptors, generally assessed exposures from spot biospecimens. Effects of early-li…
View article: Effects of first-generation in utero exposure to diesel engine exhaust on second-generation placental function, fatty acid profiles and foetal metabolism in rabbits: preliminary results
Effects of first-generation in utero exposure to diesel engine exhaust on second-generation placental function, fatty acid profiles and foetal metabolism in rabbits: preliminary results Open
View article: Effects of dietary arginine supplementation in pregnant mares on maternal metabolism, placental structure and function and foal growth
Effects of dietary arginine supplementation in pregnant mares on maternal metabolism, placental structure and function and foal growth Open
Foals born to primiparous mares are lighter and less mature than those born to multiparous dams. Factors driving this difference are not totally understood. Using 7 multiparous and 6 primiparous standardbred mares, we demonstrated that, in…
View article: Repeated gestational exposure to diesel engine exhaust affects the fetal olfactory system and alters olfactory-based behavior in rabbit offspring
Repeated gestational exposure to diesel engine exhaust affects the fetal olfactory system and alters olfactory-based behavior in rabbit offspring Open
View article: Effects of maternal au-np exposure by inhalation on foeto-placental development and placental function, in a rabbit model
Effects of maternal au-np exposure by inhalation on foeto-placental development and placental function, in a rabbit model Open
International audience