Anne Forhan
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View article: A meta-analysis of pre-pregnancy maternal body mass index and placental DNA methylation identifies 27 CpG sites with implications for mother-child health
A meta-analysis of pre-pregnancy maternal body mass index and placental DNA methylation identifies 27 CpG sites with implications for mother-child health Open
Higher maternal pre-pregnancy body mass index (ppBMI) is associated with increased neonatal morbidity, as well as with pregnancy complications and metabolic outcomes in offspring later in life. The placenta is a key organ in fetal developm…
View article: Predictors of maternal dietary quality and dietary inflammation during pregnancy: An individual participant data meta-analysis of seven European cohorts from the ALPHABET consortium
Predictors of maternal dietary quality and dietary inflammation during pregnancy: An individual participant data meta-analysis of seven European cohorts from the ALPHABET consortium Open
View article: Associations between maternal eating behaviors and feeding practices in toddlerhood
Associations between maternal eating behaviors and feeding practices in toddlerhood Open
View article: Low Maternal DLK1 Levels at 26 Weeks Is Associated With Small for Gestational Age at Birth
Low Maternal DLK1 Levels at 26 Weeks Is Associated With Small for Gestational Age at Birth Open
Detecting SGA (small for gestational age) during pregnancy improves the fetal and neonatal prognosis. To date, there is no valid antenatal biomarker of SGA used in clinical practice. Maternal circulating DLK1 (delta-like non-canonical notc…
View article: Sleep duration trajectories associated with levels of specific serum cytokines at age 5: A longitudinal study in preschoolers from the EDEN birth cohort
Sleep duration trajectories associated with levels of specific serum cytokines at age 5: A longitudinal study in preschoolers from the EDEN birth cohort Open
View article: Pregnancy exposure to phthalates and DNA methylation in male placenta — An epigenome-wide association study
Pregnancy exposure to phthalates and DNA methylation in male placenta — An epigenome-wide association study Open
View article: A meta-analysis of pre-pregnancy maternal body mass index and placental DNA methylation identifies 27 CpG sites with implications for mother-child health
A meta-analysis of pre-pregnancy maternal body mass index and placental DNA methylation identifies 27 CpG sites with implications for mother-child health Open
Higher maternal pre-pregnancy body mass index (ppBMI) is associated with increased neonatal morbidity, as well as with pregnancy complications and metabolic outcomes in offspring later in life. Placenta is a key organ in fetal development …
View article: A meta-analysis of pre-pregnancy maternal body mass index and placental DNA methylation identifies 27 CpG sites with implications for mother-child health
A meta-analysis of pre-pregnancy maternal body mass index and placental DNA methylation identifies 27 CpG sites with implications for mother-child health Open
Higher maternal pre-pregnancy body mass index (ppBMI) is associated with increased neonatal morbidity, as well as with pregnancy complications and metabolic outcomes in offspring later in life. Placenta is a key organ in fetal development …
View article: Prospective associations between dietary patterns, screen and outdoor play times at 2 years and age at adiposity rebound: The EDEN mother-child cohort
Prospective associations between dietary patterns, screen and outdoor play times at 2 years and age at adiposity rebound: The EDEN mother-child cohort Open
Although an early adiposity rebound (AR) is an established risk factor for later obesity, little is known regarding its determinants, especially modifiable ones. Using data from the French EDEN mother-child cohort (1903 children born in 20…
View article: Association between dietary patterns reflecting one-carbon metabolism nutrients intake before pregnancy and placental DNA methylation
Association between dietary patterns reflecting one-carbon metabolism nutrients intake before pregnancy and placental DNA methylation Open
The preconception period represents an important window for foetal and epigenetic programming. Some micronutrients (B vitamins, choline, betaine, methionine) implicated in one-carbon metabolism (OCM) are essential for major epigenetic proc…
View article: Pregnancy exposure to phthalates and placental DNA methylation in the French EDEN cohort
Pregnancy exposure to phthalates and placental DNA methylation in the French EDEN cohort Open
International audience
View article: Pregnancy exposure to synthetic phenols and placental DNA methylation — An epigenome-wide association study in male infants from the EDEN cohort
Pregnancy exposure to synthetic phenols and placental DNA methylation — An epigenome-wide association study in male infants from the EDEN cohort Open
In utero exposure to environmental chemicals, such as synthetic phenols, may alter DNA methylation in different tissues, including placenta - a critical organ for fetal development. We studied associations between prenatal urinary biomarke…
View article: Associations between Infant Dietary Intakes and Liking for Sweetness and Fattiness Sensations in 8-to-12-Year-Old Children
Associations between Infant Dietary Intakes and Liking for Sweetness and Fattiness Sensations in 8-to-12-Year-Old Children Open
An exposure to sweetened and fatty foods early in life may be involved in high liking later in life. The objective is to investigate the association between dietary exposure to carbohydrate, sugars and fat in infancy, with liking for sweet…
View article: Exposure to screens and children’s language development in the EDEN mother–child cohort
Exposure to screens and children’s language development in the EDEN mother–child cohort Open
View article: Association between perinatal factors, genetic susceptibility to obesity and age at adiposity rebound in children of the EDEN mother–child cohort
Association between perinatal factors, genetic susceptibility to obesity and age at adiposity rebound in children of the EDEN mother–child cohort Open
View article: 594 Sleep Trajectories Between the Age of 2 and 5 are Associated with Blood Cytokine Levels at Age 5 in the EDEN Birth-Cohort Study
594 Sleep Trajectories Between the Age of 2 and 5 are Associated with Blood Cytokine Levels at Age 5 in the EDEN Birth-Cohort Study Open
Introduction There is a reciprocal interaction between sleep and the immune system. Activation of the immune system changes the quality of sleep, and sleep regulates innate and adaptive immune responses. While these interactions have been …
View article: 589 Sleep features longitudinally associated with refractive errors in preschoolers
589 Sleep features longitudinally associated with refractive errors in preschoolers Open
Introduction Refractive errors are very common, in particular in children and adolescents, leading to global health issues, academic implications and economic costs. The process of emmetropization in child development is a multifactorial a…
View article: Longitudinal association between sleep features and refractive errors in preschoolers from the EDEN birth-cohort
Longitudinal association between sleep features and refractive errors in preschoolers from the EDEN birth-cohort Open
Refractive errors are common, especially in children and adolescents, leading to global health issues, academic implications and economic costs. Circadian rhythm and sleep habits may play a role. The study included 1130 children from the E…
View article: Associations between Children’s Genetic Susceptibility to Obesity, Infant’s Appetite and Parental Feeding Practices in Toddlerhood
Associations between Children’s Genetic Susceptibility to Obesity, Infant’s Appetite and Parental Feeding Practices in Toddlerhood Open
Previous findings suggest that parental feeding practices may adapt to children’s eating behavior and sex, but few studies assessed these associations in toddlerhood. We aimed to study the associations between infant’s appetite or children…
View article: The EU Child Cohort Network’s core data: establishing a set of findable, accessible, interoperable and re-usable (FAIR) variables
The EU Child Cohort Network’s core data: establishing a set of findable, accessible, interoperable and re-usable (FAIR) variables Open
View article: Diet during pregnancy: Influence of social characteristics and migration in the ELFE cohort
Diet during pregnancy: Influence of social characteristics and migration in the ELFE cohort Open
Better adherence to dietary guidelines during pregnancy is supposed to result in healthier perinatal outcomes. We aim to characterize the diets of pregnant women by hypothesis‐driven and exploratory approaches and describe potential social…
View article: Association between dietary patterns reflecting one-carbon metabolism nutrients intake before pregnancy and placental DNA methylation
Association between dietary patterns reflecting one-carbon metabolism nutrients intake before pregnancy and placental DNA methylation Open
The preconception period represents an important window for foetal and epigenetic programming. Some micronutrients (B vitamins, choline, betaine, methionine) implicated in one-carbon metabolism (OCM) are essential for major epigenetic proc…
View article: Pregnancy outcomes in women with preexisting thyroid diseases: a French cohort study
Pregnancy outcomes in women with preexisting thyroid diseases: a French cohort study Open
Women with thyroid diseases at the beginning of pregnancy may have suboptimal thyroid hormone levels because of potential difficulties in compensating for the physiological thyroid hormone changes occurring in pregnancy. Our objective was …
View article: Prenatal Diet and Children's Trajectories of Anxiety and Depression Symptoms from 3 to 8 Years: The EDEN Mother-Child Cohort
Prenatal Diet and Children's Trajectories of Anxiety and Depression Symptoms from 3 to 8 Years: The EDEN Mother-Child Cohort Open
View article: Immediate and durable effects of maternal tobacco consumption alter placental DNA methylation in enhancer and imprinted gene-containing regions
Immediate and durable effects of maternal tobacco consumption alter placental DNA methylation in enhancer and imprinted gene-containing regions Open
View article: Immune activity at birth and later psychopathology in childhood
Immune activity at birth and later psychopathology in childhood Open
Disruption of neurodevelopmental trajectories can alter brain circuitry and increase the risk of psychopathology later in life. While preclinical studies have demonstrated that the immune system and cytokines influence neurodevelopment, wh…
View article: Night-sleep Duration Trajectories and Behavior in Preschoolers: Results from a Prospective Birth Cohort Study
Night-sleep Duration Trajectories and Behavior in Preschoolers: Results from a Prospective Birth Cohort Study Open
Background: Short sleep duration is associated with concomitant behavioral difficulties, but the longitudinal association between sleep duration and later behavior in early childhood remains unclear. The aim was to study the associa…
View article: The association between the maternal dietary intake of methyl-donors and birth anthropometry in the French EDEN cohort
The association between the maternal dietary intake of methyl-donors and birth anthropometry in the French EDEN cohort Open
International audience
View article: Association between Dietary Intake of One-Carbon Metabolism Nutrients in the Year before Pregnancy and Birth Anthropometry
Association between Dietary Intake of One-Carbon Metabolism Nutrients in the Year before Pregnancy and Birth Anthropometry Open
Few studies have evaluated the role of methylation-pathway nutrients involved in fetal growth (B vitamins, choline, betaine, and methionine). These one-carbon metabolism (OCM) nutrients are essential for DNA methylation in the periconcepti…
View article: Does cord blood leptin level mediate the association between neonatal body size and postnatal growth? Results from the EDEN mother–child cohort study
Does cord blood leptin level mediate the association between neonatal body size and postnatal growth? Results from the EDEN mother–child cohort study Open
Background: Leptin is potentially involved in the correction of early postnatal growth of infants having deviated from their genetic trajectory in utero. Aim: To analyse the potential mediating role of cord blood leptin level…