Explanipedia

Intracerebral hemorrhage (ICH) in easternmost Finland 2021–2023 Open

Jussi Sipilä, J. Toivanen, Juha Pääkkönen, Lisanne J. Balk, Mohamed Hassan , et al. · 2025

Aim: To report the incidence, characteristics, and prognosis of spontaneous intracerebral hemorrhage (ICH) in North Karelia Central Hospital Primary Stroke Center (PSC). Methods: All patients admitted with ICH to North Karelia Central Hosp…

Defining MRI-based follow-up protocol for primary central nervous system lymphoma Open

Inka Puhakka, Kaisa Sunela, Aino Rönkä, Aino Rajamäki, Ulla‐Mari Arkko , et al. · 2024

Background The optimal follow-up protocol for primary central nervous system lymphoma (PCNSL) is unclear. This is the first study to evaluate the benefit of structured follow-up imaging of PCNSL with respect to the timing of relapse. Metho…

Is there a role for structural MRI in PCNSL follow-up? Open

Inka Puhakka, Kaisa Sunela, Aino Rönkä, Aino Rajamäki, Ulla‐Mari Arkko , et al. · 2024

Background The optimal follow-up protocol for primary central nervous system lymphoma (PCNSL) is unclear. This is the first study to evaluate the benefit of structured follow-up imaging of PCNSL with respect to the timing of relapse. Metho…

When is it time for palliative and end-of-life care in status epilepticus? Open

Reetta Kälviäinen, Zakarya Allal, Anne-Mari Kantanen · 2023

Status epilepticus (SE) is a neurological emergency characterized by high rates of short-term and long-term morbidity and mortality. Status epilepticus seems to be a marker of the severity of other underlying conditions rather than a deter…

The development of emergency medical services benefit score: a European Delphi study Open

Anssi Heino, Lasse Raatiniemi, Timo Iirola, Merja Meriläinen, Janne Liisanantti , et al. · 2021

Using common genetic variants to find drugs for common epilepsies Open

Nasir Mirza, Remi Stevelink, Basel A. Taweel, Bobby P.C. Koeleman, Anthony G Marson , et al. · 2021

Better drugs are needed for common epilepsies. Drug repurposing offers the potential of significant savings in the time and cost of developing new treatments. In order to select the best candidate drug(s) to repurpose for a disease, it is …

Status epilepticus: Practice variation and adherence to treatment guideline in a large community hospital Open

Joni J. Sairanen, Anne-Mari Kantanen, Harri Hyppölä, Reetta Kälviäinen · 2021

Prompt and effective pharmacotherapy is the cornerstone of good SE treatment. Subtherapeutic doses of first-line benzodiazepines should be avoided. Benzodiazepine-resistant SE must be recognized early to facilitate rapid treatment escalati…

The selection of an optimal transportation strategy in urgent stroke missions: a simulation study Open

Jukka Pappinen, Tuuli Miettinen, Päivi Laukkanen‐Nevala, Pekka Jäkälä, Anne-Mari Kantanen , et al. · 2020

Acute stroke and TIA patients have specific polygraphic features of obstructive sleep apnea Open

Akseli Leino, Susanna Westerén-Punnonen, Juha Töyräs, Sami Myllymaa, Timo Leppänen , et al. · 2020

Purpose Obstructive sleep apnea (OSA) is associated with increased risk for stroke, which is known to further impair respiratory functions. However, it is unknown whether the type and severity of respiratory events are linked to stroke or …

Outcome of status epilepticus and the predictive value of the EMSE and STESS scores: A prospective study Open

Joni J. Sairanen, Anne-Mari Kantanen, Harri Hyppölä, Reetta Kälviäinen · 2020

Incidence of the different stages of status epilepticus in Eastern Finland: A population-based study Open

Anne-Mari Kantanen, Joni J. Sairanen, Reetta Kälviäinen · 2019

The new ILAE 2015 definition of SE resulted in a four-fold increase in incidence of SE compared to the earlier 30-min definition reported earlier in Europe. In the epidemiology of RSE, the incidence of ICU-treated RSE, palliatively treated…

Treatment delay in status epilepticus – more effective prehospital symptom recognition warranted Open

Joni J. Sairanen, Anne-Mari Kantanen, Harri Hyppölä, Reetta Kälviäinen · 2019

Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies Open

Bassel Abou‐Khalil, Pauls Auce, Andreja Avberšek, Melanie Bahlo, David J. Balding , et al. · 2018

Intensive care treated refractory status epilepticus : incidence and outcome in Finland 2010-2012 Open

Anne-Mari Kantanen · 2017

Long-term outcome of refractory status epilepticus in adults: A retrospective population-based study Open

Anne-Mari Kantanen, Matti Reinikainen, Ilkka Parviainen, Reetta Kälviäinen · 2017

During 1-year follow-up, nearly 50% of the ICU-treated RSE patients recovered to baseline function, whereas 30% showed new functional defects and 20% died. SRSE does not have a necessarily poorer outcome. The outcome is worse in older pati…

Predictors of hospital and one-year mortality in intensive care patients with refractory status epilepticus: a population-based study Open

Anne-Mari Kantanen, Reetta Kälviäinen, Ilkka Parviainen, Marika Ala-Peijari, Tom Bäcklund , et al. · 2017

Retrospective registry study; no interventions on human participants.

Tunnistatko aivoinfarktin trombektomiakandidaatin Open

Perttu J. Lindsberg, Anne-Mari Kantanen, Olli S. Mattila, Lauri Soinne, Tuukka Puolakka , et al. · 2017

Clinical Characteristics of Patients with Suspected Cardioembolic Stroke/TIA. Open

Mikko Taina, Sipola Petri, Muuronen Antti, Hedman Marja, Mustonen Pirjo , et al. · 2015

The left atrial appendage (LAA) volume was measured in 149 cardiogenic stroke/TIA patients without chronic atrial fibrillation. Open

Mikko Taina, Petri Sipola, Antti Muuronen, Marja Hedman, Pirjo Mustonen , et al. · 2015

There were 18 different variables to determine factors that increase LAA volume. Patients were dichotomized by the measurements performed with transthoracic echocardiography following the guidelines of the American Society of Echocardiogra…

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