Sallie‐Anne Pearson
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View article: Effectiveness of smoking cessation pharmacotherapies during pregnancy: A multi‐national population‐based study
Effectiveness of smoking cessation pharmacotherapies during pregnancy: A multi‐national population‐based study Open
Aims As clinical trial evidence on the effectiveness of smoking cessation pharmacotherapies during pregnancy is inconclusive, we conducted a large cohort study examining their effectiveness and comparative effectiveness during pregnancy. D…
View article: Polypharmacy among people diagnosed with colorectal cancer in Australia: a population-based cohort study
Polypharmacy among people diagnosed with colorectal cancer in Australia: a population-based cohort study Open
Background Polypharmacy is associated with increased risks of adverse outcomes in people with cancer and medicine use evolves over the course of the disease trajectory. We estimated the prevalence of polypharmacy in people with colorectal …
View article: Measuring Exposure to Opioids Using Self‐Reported Medication Use Data Versus General Practitioner Prescription Records in the <scp>UK</scp> Biobank Study
Measuring Exposure to Opioids Using Self‐Reported Medication Use Data Versus General Practitioner Prescription Records in the <span>UK</span> Biobank Study Open
Purpose The ongoing global increase in opioid use necessitates studies examining long‐term health impacts. Prospective cohorts frequently rely on self‐reported medication use data which may be subject to several types of bias compared to m…
View article: Risk of self-harm and suicide associated with the use of opioid analgesics
Risk of self-harm and suicide associated with the use of opioid analgesics Open
Background Research suggests that there may be an association between prescribed opioid use and suicide-related behaviours. Aims This 15-year retrospective population-based cohort study examines the relationship between opioid use, self-ha…
View article: Patterns of follow-up testing of abnormal eGFR and UACR for the detection of chronic kidney disease in Australian primary care: analysis of a national general practice dataset
Patterns of follow-up testing of abnormal eGFR and UACR for the detection of chronic kidney disease in Australian primary care: analysis of a national general practice dataset Open
Objective To evaluate the patterns of abnormal estimated glomerular filtration rate (eGFR) and urine albumin–creatinine ratio (UACR) follow-up testing for the detection of chronic kidney disease (CKD) in Australian general practices. Desig…
View article: The Temptations of Trite: How Policymakers Avoid Addressing Homelessness as a Structural Challenge
The Temptations of Trite: How Policymakers Avoid Addressing Homelessness as a Structural Challenge Open
Where governments deny homelessness exists, researchers and advocates need to guide the changes and make the right to adequate housing a reality.
View article: The Temptations of Trite: How Policymakers Avoid Addressing Homelessness as a Structural Challenge
The Temptations of Trite: How Policymakers Avoid Addressing Homelessness as a Structural Challenge Open
Where governments deny homelessness exists, researchers and advocates need to guide the changes and make the right to adequate housing a reality.
View article: Corrigendum to “Missed opportunities in HCV care: Trends in late diagnosis and treatment” [JHEP Reports 7 (2025) 101474]
Corrigendum to “Missed opportunities in HCV care: Trends in late diagnosis and treatment” [JHEP Reports 7 (2025) 101474] Open
[This corrects the article DOI: 10.1016/j.jhepr.2025.101474.].
View article: Transparent reporting of observational studies emulating a target trial: the TARGET Statement
Transparent reporting of observational studies emulating a target trial: the TARGET Statement Open
Importance When randomized trials are unavailable or not feasible, observational studies can be used to answer causal questions about the comparative effects of interventions by attempting to emulate a hypothetical pragmatic randomized tri…
View article: Prevalence of <scp>SGLT2</scp> inhibitor and <scp>GLP1</scp> receptor agonist prescriptions in type 2 diabetes patients with and without chronic kidney disease: Analysis of an Australian primary care dataset
Prevalence of <span>SGLT2</span> inhibitor and <span>GLP1</span> receptor agonist prescriptions in type 2 diabetes patients with and without chronic kidney disease: Analysis of an Australian primary care dataset Open
Aims Sodium‐glucose co‐transporter 2 inhibitors (SGLT2 inhibitors) and glucagon‐like peptide‐1 receptor agonists (GLP1‐RA) have cardio‐kidney‐metabolic benefit. This study aimed to understand the prevalence of prescription of SGLT2 inhibit…
View article: Variation in uptake of sodium glucose cotransporter 2 inhibitors and glucagon-like peptide-1 receptor analogues in adults with type 2 diabetes at high cardiovascular risk
Variation in uptake of sodium glucose cotransporter 2 inhibitors and glucagon-like peptide-1 receptor analogues in adults with type 2 diabetes at high cardiovascular risk Open
Purpose We quantified variation in the uptake of sodium-glucose co-transporter 2 inhibitors (SGLT2i) and glucagon-like peptide-1 receptor analogues (GLP-1RA) across sociodemographic, behavioural and clinical characteristics of people with …
View article: Reduced Use of Maintenance Therapies Among People With Cystic Fibrosis Following Initiation of Elexacaftor/Tezacaftor/Ivacaftor in Australia
Reduced Use of Maintenance Therapies Among People With Cystic Fibrosis Following Initiation of Elexacaftor/Tezacaftor/Ivacaftor in Australia Open
Elexacaftor/tezacaftor/ivacaftor is associated with a reduced treatment burden in cystic fibrosis, supporting broader access.
View article: Missed opportunities in HCV care: Trends in late diagnosis and treatment
Missed opportunities in HCV care: Trends in late diagnosis and treatment Open
Timely HCV care is essential to prevent liver disease progression. Significant improvements in HCV diagnosis and treatment timing in New South Wales over the past decade highlight the success of Australia's universal provision of direct-ac…
View article: Estimation of the Duration of Antihypertensive Prescriptions: Validation of a Data‐Driven Approach Using Rotterdam Study Data
Estimation of the Duration of Antihypertensive Prescriptions: Validation of a Data‐Driven Approach Using Rotterdam Study Data Open
Objectives Administrative medicine dispensing data often omit prescribed duration, which is important for research on adherence or other pharmacoepidemiological topics. While the reverse waiting time distribution (rWTD) method has been wid…
View article: Analysis of 2023 World Health Organization cancer Essential Medicines List and concordance with resource-stratified guidelines
Analysis of 2023 World Health Organization cancer Essential Medicines List and concordance with resource-stratified guidelines Open
Background The World Health Organization (WHO) Essential Medicines List (EML) and resource-stratified guidelines both prioritize high-value medicines. We compared the 2023 EML cancer medicines list with global cancer statistics, examined t…
View article: Trends in cause-specific mortality among people with hepatitis C virus in New South Wales, Australia
Trends in cause-specific mortality among people with hepatitis C virus in New South Wales, Australia Open
During the HCV elimination era, both liver-related and drug-related mortality have declined, suggesting direct and indirect impacts of DAA therapy, respectively. Expanded opioid agonist therapy coverage and enhanced alcohol use disorder ma…
View article: Risk of Major Congenital Malformations Following Prenatal Exposure to Smoking Cessation Medicines
Risk of Major Congenital Malformations Following Prenatal Exposure to Smoking Cessation Medicines Open
Importance Nicotine replacement therapy (NRT), varenicline, and bupropion are effective smoking cessation pharmacotherapies, but evidence on fetal safety is limited. Objective To assess whether prenatal use of smoking cessation pharmacothe…
View article: Addressing health equity during design and implementation of health system reform initiatives: a scoping review and framework
Addressing health equity during design and implementation of health system reform initiatives: a scoping review and framework Open
This review synthesises diverse literature about how health equity has been considered across levels of the health system during reform design and implementation, providing to our knowledge, the first comprehensive multi-level approach to …
View article: Corrigendum to Antipsychotic use during pregnancy and risk of specific neurodevelopmental disorders and learning difficulties in children: a multinational cohort study [eClinicalMedicine 70 (2024) 102531/DOI: 10.1016/j.eclinm.2024.102531]
Corrigendum to Antipsychotic use during pregnancy and risk of specific neurodevelopmental disorders and learning difficulties in children: a multinational cohort study [eClinicalMedicine 70 (2024) 102531/DOI: 10.1016/j.eclinm.2024.102531] Open
[This corrects the article DOI: 10.1016/j.eclinm.2024.102531.].
View article: Long-acting, progestin-based contraceptives and risk of breast, gynecological, and other cancers
Long-acting, progestin-based contraceptives and risk of breast, gynecological, and other cancers Open
Background Use of long-acting, reversible contraceptives has increased over the past 20 years, but an understanding of how they could influence cancer risk is limited. Methods We conducted a nested case-control study among a national cohor…
View article: Trends in prescription opioid analgesic use in Australia from 2015 to 2022
Trends in prescription opioid analgesic use in Australia from 2015 to 2022 Open
Prescribed opioid analgesic use declined between 2015 and 2022 because of reductions in PBS dispensing claims. A quarter of the reduction in PBS dispensing claims was offset by use outside the PBS. Our findings indicate a significant incre…
View article: Effects of clinical and socioeconomic factors on Medicare and patient costs for colorectal cancer in Australia: a retrospective multivariate regression analysis
Effects of clinical and socioeconomic factors on Medicare and patient costs for colorectal cancer in Australia: a retrospective multivariate regression analysis Open
Objective We study how clinical and socioeconomic factors influence colorectal cancer (CRC) costs for patients and Medicare in Australia. The study seeks to extend the limited Australian literature on CRC costs by analysing comprehensive p…
View article: Patterns of medicine use in the year prior to death by suicide: an Australian population-based case series study
Patterns of medicine use in the year prior to death by suicide: an Australian population-based case series study Open
This study is funded by a grant from the Australian National Health and Medical Research Council (NHMRC) and the Translational Australian Clinical Toxicology Research (TACT) Group.
View article: Use of, time to, and type of first add‐on anti‐hyperglycaemic therapy to metformin in Australia, 2018–2022
Use of, time to, and type of first add‐on anti‐hyperglycaemic therapy to metformin in Australia, 2018–2022 Open
Aims The aim of this study was to examine contemporary trends in the use of, time to, and type of first add‐on anti‐hyperglycaemic therapy to metformin in Australia. Methods We used the dispensing records of a 10% random sample of Pharmace…
View article: Trends in viral hepatitis liver-related morbidity and mortality in New South Wales, Australia
Trends in viral hepatitis liver-related morbidity and mortality in New South Wales, Australia Open
The Kirby Institute, UNSW Sydney, and New South Wales Ministry of Health, Australia.
View article: The Medicines Intelligence Data Platform: A Population‐Based Data Resource From New South Wales, Australia
The Medicines Intelligence Data Platform: A Population‐Based Data Resource From New South Wales, Australia Open
Background The Medicines Intelligence (MedIntel) Data Platform is an anonymised linked data resource designed to generate real‐world evidence on prescribed medicine use, effectiveness, safety, costs and cost‐effectiveness in Australia. Res…