Anne Poder Andersen
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View article: Development of a bispecific immune engager using a recombinant malaria protein
Development of a bispecific immune engager using a recombinant malaria protein Open
View article: Pyrazine ring-based Na+/H+ exchanger (NHE) inhibitors potently inhibit cancer cell growth in 3D culture, independent of NHE1
Pyrazine ring-based Na+/H+ exchanger (NHE) inhibitors potently inhibit cancer cell growth in 3D culture, independent of NHE1 Open
View article: The acid-base transport proteins NHE1 and NBCn1 regulate cell cycle progression in human breast cancer cells
The acid-base transport proteins NHE1 and NBCn1 regulate cell cycle progression in human breast cancer cells Open
Precise acid-base homeostasis is essential for maintaining normal cell proliferation and growth. Conversely, dysregulated acid-base homeostasis, with increased acid extrusion and marked extracellular acidification, is an enabling feature o…
View article: The acid-base transport proteins NHE1 and NBCn1 regulate cell cycle progression in human breast cancer cells
The acid-base transport proteins NHE1 and NBCn1 regulate cell cycle progression in human breast cancer cells Open
Precise acid-base homeostasis is essential for maintaining normal cell proliferation and growth. Conversely, dysregulated acid-base homeostasis, with increased acid extrusion and marked extracellular acidification, is an enabling feature o…
View article: The net acid extruders NHE1, NBCn1 and MCT4 promote mammary tumor growth through distinct but overlapping mechanisms
The net acid extruders NHE1, NBCn1 and MCT4 promote mammary tumor growth through distinct but overlapping mechanisms Open
High metabolic and proliferative rates in cancer cells lead to production of large amounts of H + and CO 2 , and as a result, net acid extruding transporters are essential for the function and survival of cancer cells. We assessed protein …
View article: The acid-base transport proteins NHE1 and NBCn1 regulate cell cycle progression in human breast cancer cells
The acid-base transport proteins NHE1 and NBCn1 regulate cell cycle progression in human breast cancer cells Open
Precise acid-base homeostasis is essential for maintaining normal cell proliferation and growth. Conversely, dysregulated acid-base homeostasis, with increased acid extrusion and marked extracellular acidification, is an enabling feature o…
View article: Roles of acid-extruding ion transporters in regulation of breast cancer cell growth in a 3-dimensional microenvironment
Roles of acid-extruding ion transporters in regulation of breast cancer cell growth in a 3-dimensional microenvironment Open
View article: Additional file 5: Figure S5. of Roles of acid-extruding ion transporters in regulation of breast cancer cell growth in a 3-dimensional microenvironment
Additional file 5: Figure S5. of Roles of acid-extruding ion transporters in regulation of breast cancer cell growth in a 3-dimensional microenvironment Open
Stability of transient siRNA-mediated knockdown of NHE1 in MDA-MB-231 cells. A. MDA-MB-231 cells were transfected with 100 nM siNHE1. 48 h after transfection, cells were reseeded and the stability of the knockdown in 2D culture was monitor…
View article: Additional file 3: Figure S3. of Roles of acid-extruding ion transporters in regulation of breast cancer cell growth in a 3-dimensional microenvironment
Additional file 3: Figure S3. of Roles of acid-extruding ion transporters in regulation of breast cancer cell growth in a 3-dimensional microenvironment Open
NHE1 Ser703 phosphorylation in spheroids and 2D culture and during spheroid growth. MCF-7 and MDA-MB-231 spheroids (3D) and 2D cultures were grown 4 and 9 (MDA-MB-231 spheroids only) days in parallel, followed by lysis and Western blotting…