Rebecca Pope
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View article: Using Natural Language Processing to Explore Patient Perspectives on AI Avatars in Support Materials for Patients With Breast Cancer: Survey Study
Using Natural Language Processing to Explore Patient Perspectives on AI Avatars in Support Materials for Patients With Breast Cancer: Survey Study Open
Background Having well-informed patients is crucial to enhancing patient satisfaction, quality of life, and health outcomes, which in turn optimizes health care use. Traditional methods of delivering information, such as booklets and leafl…
View article: Re-Audit of Physical Health Equipment Available at the Mount Old Age Psychiatric Hospital
Re-Audit of Physical Health Equipment Available at the Mount Old Age Psychiatric Hospital Open
Aims: The purpose of this audit was to re-audit (second cycle) the availability of physical health equipment on the psychiatric wards at the Mount psychiatric hospital. This was a second cycle of a previous audit performed in November 2023…
View article: A scoping review of the use of artificial intelligence models in automated OCT analysis and prediction of treatment outcomes in diabetic macular oedema
A scoping review of the use of artificial intelligence models in automated OCT analysis and prediction of treatment outcomes in diabetic macular oedema Open
Objective: This review aims to identify gaps and provide direction for future research examining the use of artificial intelligence (AI) and optical coherence tomography (OCT) in the investigation and management of diabetic macular oedema …
View article: GIF: An Automated Genomic Information Finder to Extract Data from Reports
GIF: An Automated Genomic Information Finder to Extract Data from Reports Open
Genomic testing is becoming increasingly used within the UK National Health Service (NHS) in an effort to deliver precision medicine that can directly benefit patient management and care. Typically, in hospital settings clinical scientists…
View article: Method to apply temporal graph analysis on electronic patient record data to explore healthcare professional–patient interaction intensity: a cohort study
Method to apply temporal graph analysis on electronic patient record data to explore healthcare professional–patient interaction intensity: a cohort study Open
Aim Interactions between patients and healthcare professionals (HCP) during hospital admissions are complex and difficult to interrogate using traditional analysis of electronic patient record (EPR) data. The objective of this study was to…
View article: Real-world learnings for digital health industry–NHS collaboration: Life sciences vision in action
Real-world learnings for digital health industry–NHS collaboration: Life sciences vision in action Open
Several publications have indicated potential benefit from collaboration with industry regarding wider use of anonymised routine NHS healthcare data. However, there is limited guidance regarding exactly how such collaborations between NHS …
View article: Communicating exploratory unsupervised machine learning analysis in age clustering for paediatric disease
Communicating exploratory unsupervised machine learning analysis in age clustering for paediatric disease Open
Background Despite the increasing availability of electronic healthcare record (EHR) data and wide availability of plug-and-play machine learning (ML) Application Programming Interfaces, the adoption of data-driven decision-making within r…
View article: 65 Automatic extraction of structured information from cardiology MRI reports
65 Automatic extraction of structured information from cardiology MRI reports Open
Background Cardiac MRI reports contain rich structured information that can be valuable for research. However, such information is present only in documents (e.g., PDFs, Word) requiring manual extraction. Manual extraction of important cli…
View article: 64 The use of graph analytics to enhance the understanding of hospital admissions for Paediatric renal transplants
64 The use of graph analytics to enhance the understanding of hospital admissions for Paediatric renal transplants Open
Aim The interactions between patients and Health Care Providers (HCPs) within a hospital admission are complex and difficult to navigate using traditional analytical approaches when applied to Electronic Patient Record (EPR) data. The coll…
View article: Inhibition of Thiamine Diphosphate-Dependent Enzymes by Triazole-Based Thiamine Analogues
Inhibition of Thiamine Diphosphate-Dependent Enzymes by Triazole-Based Thiamine Analogues Open
Thiamine is metabolized into the coenzyme thiamine diphosphate (ThDP). Interrupting thiamine utilization leads to disease states. Oxythiamine, a thiamine analogue, is metabolized into oxythiamine diphosphate (OxThDP), which inhibits ThDP-d…
View article: Inhibition of Thiamine Diphosphate (ThDP)-dependent Enzymes by Triazole-based Thiamine Analogues
Inhibition of Thiamine Diphosphate (ThDP)-dependent Enzymes by Triazole-based Thiamine Analogues Open
Thiamine (vitamin B1) is metabolised into the coenzyme thiamine diphosphate (ThDP). Interrupting thiamine-utilisation leads to disease states and thiamine/ThDP analogues are commonly used as antagonists of thiamine-utilisation pathways to …
View article: Individual and combined effects of cannabidiol and Δ<sup>9</sup>-tetrahydrocannabinol on striato-cortical connectivity in the human brain
Individual and combined effects of cannabidiol and Δ<sup>9</sup>-tetrahydrocannabinol on striato-cortical connectivity in the human brain Open
Background: Cannabidiol (CBD) and Δ 9 -tetrahydrocannabinol (THC) are the two major constituents of cannabis with contrasting mechanisms of action. THC is the major psychoactive, addiction-promoting, and psychotomimetic compound, while CBD…
View article: The Effect of Right Temporal Lobe Gliomas on Left and Right Hemisphere Neural Processing During Speech Perception and Production Tasks
The Effect of Right Temporal Lobe Gliomas on Left and Right Hemisphere Neural Processing During Speech Perception and Production Tasks Open
Using fMRI, we investigated how right temporal lobe gliomas affecting the posterior superior temporal sulcus alter neural processing observed during speech perception and production tasks. Behavioural language testing showed that three pre…
View article: A Meta-embedding-based Ensemble Approach for ICD Coding Prediction
A Meta-embedding-based Ensemble Approach for ICD Coding Prediction Open
International Classification of Diseases (ICD) are the de facto codes used globally for clinical coding. These codes enable healthcare providers to claim reimbursement and facilitate efficient storage and retrieval of diagnostic informatio…
View article: Individual and combined effects of Cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC) on striato-cortical connectivity in the human brain
Individual and combined effects of Cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC) on striato-cortical connectivity in the human brain Open
Cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC) are two major constituents of cannabis with contrasting mechanisms of action. THC is the major psychoactive, addiction-promoting, and psychotomimetic compound, while CBD may have somewhat…
View article: 45 Predicting long length of stay in a paediatric intensive care unit using machine learning
45 Predicting long length of stay in a paediatric intensive care unit using machine learning Open
Introduction Length of stay (LOS) prediction modelling in intensive care units is a valuable capacity planning tool as hospitals attempt to clear the backlog of surgical patients resulting from the COVID-19 pandemic. Recent work in adults …
View article: Predictors of emergency department attendance following NHS 111 calls for children and young people: analysis of linked data
Predictors of emergency department attendance following NHS 111 calls for children and young people: analysis of linked data Open
Objectives To assess whether clinical input during calls to the NHS 111 telephone-based advice service is associated with lower rates of subsequent emergency department attendance and hospital admission. Design Although NHS 111 largely emp…
View article: Factors affecting seizure outcome after epilepsy surgery: an observational series
Factors affecting seizure outcome after epilepsy surgery: an observational series Open
Readily identified clinical features and investigations are associated with reduced probability of good outcome and need consideration when planning presurgical evaluation.
View article: Cannabis Dampens the Effects of Music in Brain Regions Sensitive to Reward and Emotion
Cannabis Dampens the Effects of Music in Brain Regions Sensitive to Reward and Emotion Open
Cannabis dampens the effects of music in brain regions sensitive to reward and emotion. These effects were offset by a key cannabis constituent, cannabidol.
View article: PM298. Dissociable effects of cannabinoids on anticipatory and consummatory reward processing
PM298. Dissociable effects of cannabinoids on anticipatory and consummatory reward processing Open
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View article: PM297. High-dose zolpidem dependence and detoxification from withdrawal symptoms using diazepam
PM297. High-dose zolpidem dependence and detoxification from withdrawal symptoms using diazepam Open
Objective: Efforts to promote the cessation of harmful alcohol use are hindered by the affective and physiological components of alcohol withdrawal (AW), which can include life-threatening seizures.Although previous studies of AW and relap…