Andrzej Wójcik
YOU?
Author Swipe
View article: Contributions of the radonorm project to European and international radiation protection research
Contributions of the radonorm project to European and international radiation protection research Open
RadoNorm has come a long way since its inception, in addressing and managing risks for radon and NORM. The output of the project has been substantial in generating new findings and developing novel methodologies and tools. At the same time…
View article: Outcome summary of the scientific program of the 16th IRPA Congress
Outcome summary of the scientific program of the 16th IRPA Congress Open
The 16th International Congress of the International Radiation Protection Association (IRPA16), held in conjunction with the 69th Annual Meeting of the Health Physics Society (HPS) in Orlando, USA, provided an excellent platform for radiat…
View article: Relationship between amino acid transporter activity and radioactive iodine therapy efficacy in differentiated thyroid cancer
Relationship between amino acid transporter activity and radioactive iodine therapy efficacy in differentiated thyroid cancer Open
Thyroid cancer is the most common malignant endocrine tumor. Differentiated thyroid cancer (DTC) accounts for 95% of thyroid cancer cases. The primary treatment for intermediate‑ and high‑risk DTC is total thyroidectomy. Postoperatively, s…
View article: MaksChroms: An open-source CNN-based tool for dose prediction based on dicentric chromosome assay
MaksChroms: An open-source CNN-based tool for dose prediction based on dicentric chromosome assay Open
View article: Essentials of the system of radiological protection
Essentials of the system of radiological protection Open
The system of radiological protection (the ‘System’) developed by the International Commission on Radiological Protection (ICRP) is built on nearly a century of efforts of numerous scientists and practitioners working together internationa…
View article: Secretion of specific metabolites and changes in miRNA expression in murine osteoblastic cells exposed <i>in vitro</i> to α‑radiation
Secretion of specific metabolites and changes in miRNA expression in murine osteoblastic cells exposed <i>in vitro</i> to α‑radiation Open
Osteoblastic cells (OBCs) in bone marrow (BM) support hematopoietic stem/progenitor cells (HSPCs) by forming a regulatory niche through cytokine and metabolite secretion. Targeted α‑emitting radionuclide therapy, such as radium‑223 dichlor…
View article: DNA damage response of U2OS cells to low doses of gamma radiation delivered at very low dose rate
DNA damage response of U2OS cells to low doses of gamma radiation delivered at very low dose rate Open
The DNA damage response (DDR) of cells to low dose and low dose rate ionizing radiation is weak and remains a matter of controversy. The response can be studied by exposing cells to a low adapting dose (AD) and, subsequently to a high chal…
View article: The vital role of radiation protection research in Europe’s future: a PIANOFORTE white paper
The vital role of radiation protection research in Europe’s future: a PIANOFORTE white paper Open
Radiation protection is a cornerstone of public health, occupational safety, patient welfare, and environmental stewardship. A strong emphasis on radiation protection is necessary to contribute to the well-being of citizens, to innovation …
View article: Predicting bone marrow suppression from urinal 8-hydroxy-2'-deoxyguanosine level during the treatment with radium-223 in patients with cancer bone metastasis
Predicting bone marrow suppression from urinal 8-hydroxy-2'-deoxyguanosine level during the treatment with radium-223 in patients with cancer bone metastasis Open
These results suggest that a urinal 8-OHdG concentration has a potency of biomarker for bone marrow suppression under the administration of radium-223 in the patient with BM from CRPC.
View article: RENEB interlaboratory comparison for biological dosimetry based on dicentric chromosome analysis and cobalt-60 exposures higher than 2.5 Gy
RENEB interlaboratory comparison for biological dosimetry based on dicentric chromosome analysis and cobalt-60 exposures higher than 2.5 Gy Open
View article: The PIANOFORTE partnership: Elevating European research for enhanced radiation protection
The PIANOFORTE partnership: Elevating European research for enhanced radiation protection Open
The PIANOFORTE partnership (2022–2029) aims to enhance radiation protection for the public, patients, workers, and the environment across various exposure scenarios. This European initiative addresses key barriers in health and environment…
View article: Biological effectiveness of combined exposure to neutrons and gamma radiation applied in two orders of sequence: Relevance for biological dosimetry after nuclear emergencies
Biological effectiveness of combined exposure to neutrons and gamma radiation applied in two orders of sequence: Relevance for biological dosimetry after nuclear emergencies Open
Objective: To investigate the potential impact of two different combinations of neutron and gamma radiation on gene expression and dicentric chromosomes in peripheral blood mononuclear cells (PBMC). Methods: Whole blood from 3 human donors…
View article: The system of radiological protection and the UN sustainable development goals
The system of radiological protection and the UN sustainable development goals Open
View article: The scientific nature of the linear no-threshold (LNT) model used in the system of radiological protection
The scientific nature of the linear no-threshold (LNT) model used in the system of radiological protection Open
View article: Characteristics of sphingomyelin metabolism in the MCF7 and BT474 radiotherapy‑resistant HER2‑positive breast cancer cell lines
Characteristics of sphingomyelin metabolism in the MCF7 and BT474 radiotherapy‑resistant HER2‑positive breast cancer cell lines Open
Breast cancer is the most common cancer globally in terms of incidence. This cancer is classified into subtypes based on histological or immunological characteristics. HER2-positive cases account for 15-25% of breast cancer cases, and one …
View article: Home-made low-cost dosemeter for photon dose measurements in radiobiological experiments and for education in the field of radiation sciences
Home-made low-cost dosemeter for photon dose measurements in radiobiological experiments and for education in the field of radiation sciences Open
Reliable dosimetry systems are crucial for radiobiological experiments either to quantify the biological consequences of ionizing radiation or to reproduce results by other laboratories. Also, they are essential for didactic purposes in th…
View article: Chromosomal damage, gene expression and alternative transcription in human lymphocytes exposed to mixed ionizing radiation as encountered in space
Chromosomal damage, gene expression and alternative transcription in human lymphocytes exposed to mixed ionizing radiation as encountered in space Open
View article: Minimum reporting standards about dosimetry of radiation sources used in radiation research studies
Minimum reporting standards about dosimetry of radiation sources used in radiation research studies Open
View article: Short- and long-term effects of radiation exposure at low dose and low dose rate in normal human VH10 fibroblasts
Short- and long-term effects of radiation exposure at low dose and low dose rate in normal human VH10 fibroblasts Open
Introduction Experimental studies complement epidemiological data on the biological effects of low doses and dose rates of ionizing radiation and help in determining the dose and dose rate effectiveness factor. Methods Human VH10 skin fibr…
View article: Impact of fractionated cisplatin and radiation treatment on cell growth and accumulation of DNA damage in two normal cell types differing in origin
Impact of fractionated cisplatin and radiation treatment on cell growth and accumulation of DNA damage in two normal cell types differing in origin Open
View article: Fluorescence in situ hybridisation for interphase chromosomal aberration-based biological dosimetry
Fluorescence in situ hybridisation for interphase chromosomal aberration-based biological dosimetry Open
Metaphase spreads stained with Giemsa or painted with chromosome-specific probes by fluorescence in situ hybridisation (FISH) have been in use since long for retrospective dose assessment (biological dosimetry). However, in cases of accide…
View article: Mechanistic insights from high resolution DNA damage analysis to understand mixed radiation exposure
Mechanistic insights from high resolution DNA damage analysis to understand mixed radiation exposure Open
Cells exposed to densely ionising high and scattered low linear energy transfer (LET) radiation (50 % dose of each) react more strongly than to the same dose of each separately. The relationship between DNA double strand break location ins…
View article: The DNA damage response to radiological imaging: from ROS and γH2AX foci induction to gene expression responses in vivo
The DNA damage response to radiological imaging: from ROS and γH2AX foci induction to gene expression responses in vivo Open
View article: The order of sequential exposure of U2OS cells to gamma and alpha radiation influences the formation and decay dynamics of NBS1 foci
The order of sequential exposure of U2OS cells to gamma and alpha radiation influences the formation and decay dynamics of NBS1 foci Open
DNA double strand breaks (DSBs) are a deleterious form of DNA damage. Densely ionising alpha radiation predominantly induces complex DSBs and sparsely ionising gamma radiation—simple DSBs. We have shown that alphas and gammas, when applied…
View article: The DNA damage response to radiological imaging: from ROS and γH2AX foci induction to gene expression responses in vivo
The DNA damage response to radiological imaging: from ROS and γH2AX foci induction to gene expression responses in vivo Open
Candidate ionising radiation exposure biomarkers must be validated in humans exposed in vivo . Blood from patients undergoing positron emission tomography - computed tomography scan (PET-CT) and skeletal scintigraphy (scintigraphy) was dra…
View article: UN Sustainable Development Goals: establishment of an electronic ‘collection’ of papers published in Radiation and Environmental Biophysics
UN Sustainable Development Goals: establishment of an electronic ‘collection’ of papers published in Radiation and Environmental Biophysics Open
View article: Vancouver call for action to strengthen expertise in radiological protection worldwide
Vancouver call for action to strengthen expertise in radiological protection worldwide Open
View article: RENEB Inter-Laboratory Comparison 2021: The Gene Expression Assay
RENEB Inter-Laboratory Comparison 2021: The Gene Expression Assay Open
Early and high-throughput individual dose estimates are essential following large-scale radiation exposure events. In the context of the Running the European Network for Biodosimetry and Physical Dosimetry (RENEB) 2021 exercise, gene expre…
View article: RENEB Inter-Laboratory Comparison 2021: Inter-Assay Comparison of Eight Dosimetry Assays
RENEB Inter-Laboratory Comparison 2021: Inter-Assay Comparison of Eight Dosimetry Assays Open
Tools for radiation exposure reconstruction are required to support the medical management of radiation victims in radiological or nuclear incidents. Different biological and physical dosimetry assays can be used for various exposure scena…
View article: Impact of fractionated cisplatin and radiation treatment on cell growth and accumulation of DNA damage in two normal cell types differing in origin
Impact of fractionated cisplatin and radiation treatment on cell growth and accumulation of DNA damage in two normal cell types differing in origin Open
Evidence on the impact of chemotherapy on radiotherapy-induced second malignant neoplasms is controversial. We estimated how cisplatin modulates the in vitro response of two normal cell types to fractionated radiation. AHH-1 lymphoblasts a…