Anneleen Kiekens
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View article: HIV and SARS-CoV-2: the interplay of two wicked problems
HIV and SARS-CoV-2: the interplay of two wicked problems Open
Funding Information: This work was funded by VLIR-UOS, grant numbers TZ2019SIN263 and TZ2020JOI032A101. Publisher Copyright: ©
View article: Learning for the Future: A Case Study of Transdisciplinary Collaboration to Improve Pandemic Preparedness
Learning for the Future: A Case Study of Transdisciplinary Collaboration to Improve Pandemic Preparedness Open
Since the World Health Organization (WHO) announced the COVID-19 pandemic, attention has turned to the impact of societal initiatives and what can be learned from them for the future beyond COVID-19. Little attention has been paid, however…
View article: Exploring the mechanisms behind HIV drug resistance in sub-Saharan Africa: conceptual mapping of a complex adaptive system based on multi-disciplinary expert insights
Exploring the mechanisms behind HIV drug resistance in sub-Saharan Africa: conceptual mapping of a complex adaptive system based on multi-disciplinary expert insights Open
View article: Qualitative systems mapping for complex public health problems: A practical guide
Qualitative systems mapping for complex public health problems: A practical guide Open
Systems mapping methods are increasingly used to study complex public health issues. Visualizing the causal relationships within a complex adaptive system allows for more than developing a holistic and multi-perspective overview of the sit…
View article: Additional file 1 of Exploring the mechanisms behind HIV drug resistance in sub-Saharan Africa: conceptual mapping of a complex adaptive system based on multi-disciplinary expert insights
Additional file 1 of Exploring the mechanisms behind HIV drug resistance in sub-Saharan Africa: conceptual mapping of a complex adaptive system based on multi-disciplinary expert insights Open
Additional file 1. HIVDR as a CAS, visualized in layers. Each element represents a factor influencing HIVDR and each line represents a connection between two factors. Factors are organized in five layers according to their connection with …
View article: Additional file 3 of Exploring the mechanisms behind HIV drug resistance in sub-Saharan Africa: conceptual mapping of a complex adaptive system based on multi-disciplinary expert insights
Additional file 3 of Exploring the mechanisms behind HIV drug resistance in sub-Saharan Africa: conceptual mapping of a complex adaptive system based on multi-disciplinary expert insights Open
Additional file 3. Interactive systems map and data set Excel file. Additional file 3 contains a weblink to an online interactive version of the systems maps included in the manuscript as Fig. 2 and Additional file 1. The second and third …
View article: Factors Associated with HIV Drug Resistance in Dar es Salaam, Tanzania: Analysis of a Complex Adaptive System
Factors Associated with HIV Drug Resistance in Dar es Salaam, Tanzania: Analysis of a Complex Adaptive System Open
HIV drug resistance (HIVDR) is a complex problem with multiple interconnected and context dependent causes. Although the factors influencing HIVDR are known and well-studied, HIVDR remains a threat to the effectiveness of antiretroviral th…
View article: Identifying mechanisms behind HIV drug resistance in Sub-Saharan Africa: a systems approach
Identifying mechanisms behind HIV drug resistance in Sub-Saharan Africa: a systems approach Open
IntroductionHIV drug resistance (HIVDR) continues to threaten the effectiveness of worldwide antiretroviral therapy (ART). Emergence and transmission of HIVDR is driven by several interconnected factors. Though much has been done to uncove…
View article: The Impact of Community Health Workers on HIV Therapy Outcome in Sub-Saharan Africa
The Impact of Community Health Workers on HIV Therapy Outcome in Sub-Saharan Africa Open
In sub-Saharan Africa, the burden on HIV care givers is high. This resulted in renewed interest in community health worker (CHW) programs. We conducted a review of the literature to summarize CHWs' effects on HIV therapy outcome. We also i…
View article: PAK6 Phosphorylates 14-3-3γ to Regulate Steady State Phosphorylation of LRRK2
PAK6 Phosphorylates 14-3-3γ to Regulate Steady State Phosphorylation of LRRK2 Open
Mutations in Leucine-rich repeat kinase 2 (LRRK2) are associated with Parkinson's disease (PD) and, as such, LRRK2 is considered a promising therapeutic target for age-related neurodegeneration. Although the cellular functions of LRRK2 in …
View article: Transdisciplinary experience in a pilot year of a new Honors Program at the KU Leuven – University of Leuven: building a team, developing and improving a transdisciplinary project through addressing a challenge on HIV drug resistance in Africa
Transdisciplinary experience in a pilot year of a new Honors Program at the KU Leuven – University of Leuven: building a team, developing and improving a transdisciplinary project through addressing a challenge on HIV drug resistance in Africa Open
Challenge: A way to understand and instruct on best practices for delivering and accepting HIV drug treatments in Africa. During this pilot year of the "Transdisciplinary Insights" Honors Program at the KU Leuven – University of Leuven, to…
View article: Exploring the value and acceptability of peer support in the process of improving adherence to HIV antiretroviral drugs in Tanzania, Dar-es-Salaam
Exploring the value and acceptability of peer support in the process of improving adherence to HIV antiretroviral drugs in Tanzania, Dar-es-Salaam Open
Challenge: A way to understand and instruct on best practices for delivering and accepting HIV drug treatments in Africa.\nThis transdisciplinary team focused on the problem of continuously rising levels of HIV drug resistance in Africa th…