Annelie Carlsson
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View article: Increased Incidence of Type 1 Diabetes and Co‐Existing Thyroid Autoimmunity During the <scp>COVID</scp> ‐19 Pandemic in Sweden
Increased Incidence of Type 1 Diabetes and Co‐Existing Thyroid Autoimmunity During the <span>COVID</span> ‐19 Pandemic in Sweden Open
Aim We aimed to investigate if the incidence of type 1 diabetes increased in children during the SARS‐CoV‐2 pandemic and whether SARS‐CoV‐2 antibodies were more frequently present at diagnosis compared with healthy individuals. We also exa…
View article: Clinical Characteristics in Swedish Children With and Without Autoantibodies at the Time of Type 1 Diabetes Diagnosis
Clinical Characteristics in Swedish Children With and Without Autoantibodies at the Time of Type 1 Diabetes Diagnosis Open
OBJECTIVE Autoantibodies have long been recognized as biomarkers of islet autoimmunity in type 1 diabetes, but their role in the pathogenesis is not fully understood. The aim of this study was to analyze clinical and hereditary characteris…
View article: Young Healthy Individuals With a First‐Degree Relative With Type 1 Diabetes Displayed Adverse Lipid Changes
Young Healthy Individuals With a First‐Degree Relative With Type 1 Diabetes Displayed Adverse Lipid Changes Open
Aim Timeline of atherosclerosis in children with type 1 diabetes is unknown. We aimed to investigate if familial risk of type 1 diabetes is associated with pro‐atherosclerotic changes. Methods Young first‐degree relatives to patients with …
View article: Childhood screening for type 1 diabetes comparing automated multiplex Antibody Detection by Agglutination-PCR (ADAP) with single plex islet autoantibody radiobinding assays
Childhood screening for type 1 diabetes comparing automated multiplex Antibody Detection by Agglutination-PCR (ADAP) with single plex islet autoantibody radiobinding assays Open
Supported by The Leona M. and Harry B. Helmsley Charitable Trust (grant number 2009-04078), the Swedish Foundation for Strategic Research (Dnr IRC15-0067) and the Swedish Research Council, Strategic Research Area (Dnr 2009-1039). AL was su…
View article: Prevalence and predictive factors for celiac disease in children with type 1 diabetes. Whom and when to screen?A nationwide longitudinal cohort study of Swedish children
Prevalence and predictive factors for celiac disease in children with type 1 diabetes. Whom and when to screen?A nationwide longitudinal cohort study of Swedish children Open
Objective: To examine the prevalence and predictive factors for celiac disease (CD) after a diagnosis of type 1 diabetes (T1D) in children and adolescent, to improve the current screening guidelines. Research Design and Methods: The associ…
View article: Prevalence and predictive factors for celiac disease in children with type 1 diabetes. Whom and when to screen?A nationwide longitudinal cohort study of Swedish children
Prevalence and predictive factors for celiac disease in children with type 1 diabetes. Whom and when to screen?A nationwide longitudinal cohort study of Swedish children Open
Objective: To examine the prevalence and predictive factors for celiac disease (CD) after a diagnosis of type 1 diabetes (T1D) in children and adolescent, to improve the current screening guidelines. Research Design and Methods: The associ…
View article: Prevalence and Predictive Factors for Celiac Disease in Children With Type 1 Diabetes: Whom and When to Screen? A Nationwide Longitudinal Cohort Study of Swedish Children
Prevalence and Predictive Factors for Celiac Disease in Children With Type 1 Diabetes: Whom and When to Screen? A Nationwide Longitudinal Cohort Study of Swedish Children Open
OBJECTIVE To examine the prevalence and predictive factors for celiac disease (CD) after a diagnosis of type 1 diabetes (T1D) in children and adolescents, to improve the current screening guidelines. RESEARCH DESIGN AND METHODS The associa…
View article: Sex differences in age of diagnosis, HLA-genotype, and autoantibody profile in children with type 1 diabetes
Sex differences in age of diagnosis, HLA-genotype, and autoantibody profile in children with type 1 diabetes Open
Objective. To examine sex differences in children with newly diagnosed type 1 diabetes (T1D) with respect to age at diagnosis, presence of autoantibodies (GADA, IA-2A, IAA, and ZnT8A), and HLA risk.Research design and Methods. A population…
View article: Sex differences in age of diagnosis, HLA-genotype, and autoantibody profile in children with type 1 diabetes
Sex differences in age of diagnosis, HLA-genotype, and autoantibody profile in children with type 1 diabetes Open
Objective. To examine sex differences in children with newly diagnosed type 1 diabetes (T1D) with respect to age at diagnosis, presence of autoantibodies (GADA, IA-2A, IAA, and ZnT8A), and HLA risk.Research design and Methods. A population…
View article: Cumulative incidence of type 1 diabetes in two cohorts of children with different national gluten recommendations in infancy
Cumulative incidence of type 1 diabetes in two cohorts of children with different national gluten recommendations in infancy Open
Aims Between 1985 and 1996, Sweden experienced an “epidemic” of celiac disease with a fourfold increase in incidence in young children. Timing and amount of gluten introduced during infancy have been thought to explain this “epidemic”. We …
View article: The prevalence of having coeliac disease in children with type 1 diabetes was not significantly higher during the Swedish coeliac epidemic
The prevalence of having coeliac disease in children with type 1 diabetes was not significantly higher during the Swedish coeliac epidemic Open
Aim From 1986 to 1996, there was a four‐fold increase in coeliac disease among young Swedish children, known as the Swedish coeliac epidemic. Children with type 1 diabetes have an increased risk of developing coeliac disease. We studied wh…
View article: Month of birth and the risk of developing type 1 diabetes among children in the Swedish national Better Diabetes Diagnosis Study
Month of birth and the risk of developing type 1 diabetes among children in the Swedish national Better Diabetes Diagnosis Study Open
Aim Previous studies have reported an association between month of birth and incidence of type 1 diabetes. Using population‐based data, including almost all newly diagnosed children with type 1 diabetes in Sweden, we tested whether month o…
View article: Does a gluten-free diet lead to better glycemic control in children with type 1 diabetes? Results from a feasibility study and recommendations for future trials
Does a gluten-free diet lead to better glycemic control in children with type 1 diabetes? Results from a feasibility study and recommendations for future trials Open
A strict GFD can be maintained by children with newly diagnosed T1D and may have positive effects on glycemic control. Our findings should be interpreted carefully because of small samples and possible confounding. We provide recommendatio…
View article: Saving lives by asking questions: nurses’ experiences of suicide risk assessment in telephone counselling in primary health care
Saving lives by asking questions: nurses’ experiences of suicide risk assessment in telephone counselling in primary health care Open
Aim: To explore nurses’ experiences of suicide risk assessment in telephone counselling (TC) in primary health care (PHC). Background: Globally, priority is given to developing suicide prevention work in PHC. However, suicide risk assessme…
View article: Five-year follow-up of new cases after a coeliac disease mass screening
Five-year follow-up of new cases after a coeliac disease mass screening Open
Objective We previously performed a population-based mass screening of coeliac disease in children aged 12 years in two birth cohorts resulting in 296 seropositive children, of whom 242 were diagnosed with coeliac disease after duodenal bi…
View article: Compliance to a Gluten-Free Diet in Swedish Children with Type 1 Diabetes and Celiac Disease
Compliance to a Gluten-Free Diet in Swedish Children with Type 1 Diabetes and Celiac Disease Open
Children with type 1 diabetes (T1D) are at increased risk of celiac disease (CD). The replacement of insulin in T1D, and the exclusion of gluten in CD, are lifelong, burdensome treatments. Compliance to a gluten-free diet (GFD) in children…
View article: Is mass screening for coeliac disease a wise use of resources? A health economic evaluation
Is mass screening for coeliac disease a wise use of resources? A health economic evaluation Open
Background Living with undiagnosed symptomatic coeliac disease is connected with deteriorated health, and persons with coeliac disease often wait a long time for their diagnosis. A mass screening would lower the delay, but its cost-effecti…
View article: Combined Etanercept, GAD‐alum and vitamin D treatment: an open pilot trial to preserve beta cell function in recent onset type 1 diabetes
Combined Etanercept, GAD‐alum and vitamin D treatment: an open pilot trial to preserve beta cell function in recent onset type 1 diabetes Open
Aim We aimed to study the feasibility and tolerability of a combination therapy consisting of glutamic acid decarboxylase (GAD‐alum), Etanercept and vitamin D in children and adolescents with newly diagnosed with type 1 diabetes (T1D), and…
View article: Celiac disease can be predicted by high levels of tissue transglutaminase antibodies in children and adolescents with type 1 diabetes
Celiac disease can be predicted by high levels of tissue transglutaminase antibodies in children and adolescents with type 1 diabetes Open
As all screened children and adolescents with T1D with tissue transglutaminase antibodies above 10 times the positive value 10x ULN had CD, we propose that the guidelines for diagnosing CD in screened children, when biopsies can be omitted…
View article: Monogenic Diabetes: From Genetic Insights to Population-Based Precision in Care. Reflections From a <i>Diabetes Care</i> Editors’ Expert Forum
Monogenic Diabetes: From Genetic Insights to Population-Based Precision in Care. Reflections From a <i>Diabetes Care</i> Editors’ Expert Forum Open
Individualization of therapy based on a person’s specific type of diabetes is one key element of a “precision medicine” approach to diabetes care. However, applying such an approach remains difficult because of barriers such as disease het…
View article: Family socio‐economic status and childhood coeliac disease seem to be unrelated—A cross‐sectional screening study
Family socio‐economic status and childhood coeliac disease seem to be unrelated—A cross‐sectional screening study Open
Aim The aim of our study was to examine whether there is a difference in coeliac disease prevalence in regard to parents' education level and occupation, and whether this differs between screened and clinically diagnosed children at the ag…