Annette Schmidt
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View article: Effects of menstrual cycle phases on athletic performance and related physiological outcomes: a systematic review of studies using high methodological standards
Effects of menstrual cycle phases on athletic performance and related physiological outcomes: a systematic review of studies using high methodological standards Open
Whether different menstrual cycle (MC) phases are associated with differences in athletic performance is a constant scientific debate. Phase verification without actual sex hormone determination and heterogeneous cohorts complicates the an…
View article: Persistent nucleic acids from endemic human coronaviruses in adenoids: Do they enhance children's immune response to SARS-CoV-2 infection?
Persistent nucleic acids from endemic human coronaviruses in adenoids: Do they enhance children's immune response to SARS-CoV-2 infection? Open
Introduction: Human Coronaviruses (HCoVs), including HCoV-OC43, HCoV-HKU1, HCoV-NL63, and HCoV-229E, are endemic viruses that circulate globally and infect humans. In contrast to SARS-CoV-2, which causes more severe symptoms, these endemic…
View article: Differential hepatic activation of mouse and human peroxisome proliferator-activated receptor-α by perfluorohexane sulfonate
Differential hepatic activation of mouse and human peroxisome proliferator-activated receptor-α by perfluorohexane sulfonate Open
Exposure of perfluorohexane sulfonate (PFHxS) is associated with hepatomegaly and accumulation of lipids that may be mediated by nuclear receptors like peroxisome proliferator-activated receptor-α (PPARα), constitutive androstane receptor …
View article: SQUARE-IT: a proposed approach to square the identified research problem in the literature with the objectives, the appropriate clinical research question, and the research hypothesis
SQUARE-IT: a proposed approach to square the identified research problem in the literature with the objectives, the appropriate clinical research question, and the research hypothesis Open
The purpose of this article is to design and introduce the SQUARE-IT approach to help scientists and clinicians in research to align important research problems with the objectives, the appropriate clinical research questions to be answere…
View article: Garmin Fénix 7® underestimates performance at the lactate threshold in comparison to standardized blood lactate field test
Garmin Fénix 7® underestimates performance at the lactate threshold in comparison to standardized blood lactate field test Open
Introduction & Purpose Lactate threshold (LT) is a critical performance measure traditionally obtained using costly laboratory-based tests. Wearables offer a practical and noninvasive alternative for LT assessment in recreational and profe…
View article: Resistance exercise snacks as a workplace health intervention
Resistance exercise snacks as a workplace health intervention Open
Introduction & Purpose Although resistance training (RT) is essential to preserve musculoskeletal fitness and maintain a healthy, independent life into old age, only 10-30% of adults perform the recommended number of 2 RT per week, with wo…
View article: Analytical Performance of the FreeStyle Libre 2 Glucose Sensor in Healthy Male Adults
Analytical Performance of the FreeStyle Libre 2 Glucose Sensor in Healthy Male Adults Open
Continuous Glucose Monitoring (CGM) not only can be used for glycemic control in chronic diseases (e.g., diabetes), but is increasingly being utilized by individuals and athletes to monitor fluctuations in training and everyday life. Howev…
View article: Music influences performance without increasing perceived exertion during high-intensity rowing intervals: a cross-over design study
Music influences performance without increasing perceived exertion during high-intensity rowing intervals: a cross-over design study Open
Objectives This study assessed how exposure to slow (SBM) versus fast beat music (FBM) during high-intensity rowing intervals affects performance, heart rate (HR), lactate levels, relative perceived exertion (RPE), and recovery. Methods Th…
View article: Effects of Concurrent Training on Resuscitation and Cognitive Performance in Paramedics—A Pilot Study
Effects of Concurrent Training on Resuscitation and Cognitive Performance in Paramedics—A Pilot Study Open
Paramedics work under physically and cognitively demanding conditions to provide emergency care. As physical fitness could positively impact the quality of patient care, we investigated within a pilot study whether concurrent training (CT)…
View article: Garmin Fénix 7® Underestimates Performance at the Lactate Threshold in Comparison to Standardized Blood Lactate Field Test
Garmin Fénix 7® Underestimates Performance at the Lactate Threshold in Comparison to Standardized Blood Lactate Field Test Open
Our results suggest sufficient accuracy of Fenix 7® LT estimates for recreational athletes. It can be assumed that for professional athletes, it would fail to provide the nuanced data needed for high-quality training management.
View article: Effects of the nerve agent VX on hiPSC-derived motor neurons
Effects of the nerve agent VX on hiPSC-derived motor neurons Open
Poisoning with the organophosphorus nerve agent VX can be life-threatening due to limitations of the standard therapy with atropine and oximes. To date, the underlying pathomechanism of VX affecting the neuromuscular junction has not been …
View article: Resistance exercise snacks improve muscle mass in female university employees: a prospective, controlled, intervention pilot-study
Resistance exercise snacks improve muscle mass in female university employees: a prospective, controlled, intervention pilot-study Open
Background Although resistance training (RT) is essential to preserve musculoskeletal fitness and maintain a healthy, independent life into old age, few women perform RT. We investigated whether resistance exercise snacking (RES) could be …
View article: Physical activity and nutrition in relation to resilience: a cross-sectional study
Physical activity and nutrition in relation to resilience: a cross-sectional study Open
View article: Persistent Nucleic Acids from Endemic Human Coronaviruses in Adenoids: Do They Enhance Children's Immune Response to Sars-Cov-2 Infection?
Persistent Nucleic Acids from Endemic Human Coronaviruses in Adenoids: Do They Enhance Children's Immune Response to Sars-Cov-2 Infection? Open
View article: Diagnostic Accuracy of Single-Lead Electrocardiograms Using the Kardia Mobile App and the Apple Watch 4: Validation Study
Diagnostic Accuracy of Single-Lead Electrocardiograms Using the Kardia Mobile App and the Apple Watch 4: Validation Study Open
Background To date, the 12-lead electrocardiogram (ECG) is the gold standard for cardiological diagnosis in clinical settings. With the advancements in technology, a growing number of smartphone apps and gadgets for recording, visualizing,…
View article: StartXFit—Nine Months of CrossFit® Intervention Enhance Cardiorespiratory Fitness and Well-Being in CrossFit Beginners
StartXFit—Nine Months of CrossFit® Intervention Enhance Cardiorespiratory Fitness and Well-Being in CrossFit Beginners Open
Insufficient physical activity (PA) is associated with low cardiorespiratory fitness, which favors cardiovascular and other noncommunicable diseases. Additionally, it evidentially affects mental health. Considering the WHO PA guidelines, C…
View article: Corrected QT Interval (QTc) Diagnostic App for the Oncological Routine: Development Study
Corrected QT Interval (QTc) Diagnostic App for the Oncological Routine: Development Study Open
Background Numerous antineoplastic drugs such as chemotherapeutics have cardiotoxic side effects and can lead to long QT syndrome (LQTS). When diagnosed and treated in time, the potentially fatal outcomes of LQTS can be prevented. Therefor…
View article: StartXFit – Nine Months of CrossFit® Intervention Enhance Cardiorespiratory Fitness and Well-Being in CrossFit Beginners
StartXFit – Nine Months of CrossFit® Intervention Enhance Cardiorespiratory Fitness and Well-Being in CrossFit Beginners Open
Insufficient physical activity (PA) is associated with low cardiorespiratory fitness, which favors cardiovascular and other non-communicable diseases. Besides, it evidentially affects mental health. Considering the WHO PA guidelines, Cross…
View article: CrossFit®: ‘Unknowable’ or Predictable?—A Systematic Review on Predictors of CrossFit® Performance
CrossFit®: ‘Unknowable’ or Predictable?—A Systematic Review on Predictors of CrossFit® Performance Open
The functional fitness training program CrossFit® is experiencing fast-growing and widespread popularity with day-to-day varying ‘Workouts of the Day’ (WOD). Even among tactical athletes, the training program is widely applied. Nevertheles…
View article: CrossFit Motivates a 41-Year-Old Obese Man to Change His Lifestyle and Achieve Long-Term Health Improvements: A Case Report
CrossFit Motivates a 41-Year-Old Obese Man to Change His Lifestyle and Achieve Long-Term Health Improvements: A Case Report Open
The purpose of this case report was to demonstrate how CrossFit (CF) as a workplace health intervention (WHI) led to long-term lifestyle changes and health improvements in an inactive, sedentary individual. Therefore, we analysed the case …
View article: Physiological effects of regular CrossFit® training and the impact of the COVID-19 pandemic—A systematic review
Physiological effects of regular CrossFit® training and the impact of the COVID-19 pandemic—A systematic review Open
CrossFit ® is a functional fitness training program known for its day-to-day varying “Workouts of the Day” (WOD). In accordance with the ‘CrossFit ® Level 1 Training Guide’, regular CrossFit® training sessions consist of Warm-up, Mobility,…
View article: The Efficiency of Direct Maturation: the Comparison of Two hiPSC Differentiation Approaches into Motor Neurons
The Efficiency of Direct Maturation: the Comparison of Two hiPSC Differentiation Approaches into Motor Neurons Open
Motor neurons (MNs) derived from human-induced pluripotent stem cells (hiPSC) hold great potential for the treatment of various motor neurodegenerative diseases as transplantations with a low-risk of rejection are made possible. There are …
View article: Sulfur mustard single-dose exposure triggers senescence in primary human dermal fibroblasts
Sulfur mustard single-dose exposure triggers senescence in primary human dermal fibroblasts Open
Chronic wounds, skin blisters, and ulcers are the result of skin exposure to the alkylating agent sulfur mustard (SM). One potential pathomechanism is senescence, which causes permanent growth arrest with a pro-inflammatory environment and…
View article: Comparison of Cardiovascular Parameters and Internal Training Load of Different 1-h Training Sessions in Non-elite CrossFit® Athletes
Comparison of Cardiovascular Parameters and Internal Training Load of Different 1-h Training Sessions in Non-elite CrossFit® Athletes Open
Purpose The fact that CrossFit ® is the best-known and rapidly growing concept for high-intensity interval training (HIIT) and high-intensity functional training (HIFT) results in a continuous increase of athletes performing CrossFit ® . I…
View article: Shifts in Self-Reported Physical Activity, Sedentary Behavior, and Play Among Lower-Socioeconomic Children During the COVID-19 Pandemic: A Repeated Cross-Sectional Study
Shifts in Self-Reported Physical Activity, Sedentary Behavior, and Play Among Lower-Socioeconomic Children During the COVID-19 Pandemic: A Repeated Cross-Sectional Study Open
Purpose The lack of in-person schooling and participation in structured recreation activities during the COVID-19 pandemic may have altered children’s movement behaviors. This study assessed changes in children’s self-reported in school an…
View article: Purchasing behavior and use of digital sports offers by CrossFit® and weightlifting athletes during the first SARS-CoV-2 lockdown in Germany
Purchasing behavior and use of digital sports offers by CrossFit® and weightlifting athletes during the first SARS-CoV-2 lockdown in Germany Open
Background To combat the spread of SARS-CoV-2, CrossFit® training centers, and fitness studios were closed during the first lockdown in Germany from mid-March until June 2020, and as a result, CrossFit® (CFA) or weightlifting athletes (WLA…
View article: Initiative on #4openScienceStandsForUkraine scientists and students
Initiative on #4openScienceStandsForUkraine scientists and students Open
are aware of the current dire
View article: High sleep quality can increase the performance of CrossFit® athletes in highly technical- and cognitive-demanding categories
High sleep quality can increase the performance of CrossFit® athletes in highly technical- and cognitive-demanding categories Open
Background In current sports science, the important role of sleep quality for health and peak performance is well acknowledged. More precisely, it is evident that the negative combination of stressful factors, low resources, and bad sleep …
View article: Determination of a CrossFit® Benchmark Performance Profile
Determination of a CrossFit® Benchmark Performance Profile Open
In the trend sport CrossFit®, international competition is held at the CrossFit® Games, known worldwide as the definitive fitness test. Since American athletes are the best in the world regarding CrossFit®, there might be influencing facto…
View article: Chronic senescent human mesenchymal stem cells as possible contributor to the wound healing disorder after exposure to the alkylating agent sulfur mustard
Chronic senescent human mesenchymal stem cells as possible contributor to the wound healing disorder after exposure to the alkylating agent sulfur mustard Open