Anni Vanhatalo
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View article: Blue plaque review series: A.V. Hill, athletic records and the birth of exercise physiology
Blue plaque review series: A.V. Hill, athletic records and the birth of exercise physiology Open
One hundred years ago, A.V. Hill authored three manuscripts analysing athletic world records from a physiological perspective. That analysis, grounded in Hill's understanding of contemporary muscle bioenergetics, provides a fascinating ske…
View article: Dose-response relationship between dietary nitrate intake and nitric oxide congeners in various blood compartments and skeletal muscle: Differential effects on skeletal muscle torque and velocity
Dose-response relationship between dietary nitrate intake and nitric oxide congeners in various blood compartments and skeletal muscle: Differential effects on skeletal muscle torque and velocity Open
Plasma nitrate (NO3-) and nitrite (NO2-) increase in a dose-dependent manner following NO3- ingestion. To explore if the same dose-response relationship applies to other nitric oxide (NO) congeners in different blood compartments and skele…
View article: The effects of inorganic nitrate and inulin co-ingestion on circulating metabolites and blood pressure in young adults: a pilot double-blind randomised crossover trial – CORRIGENDUM
The effects of inorganic nitrate and inulin co-ingestion on circulating metabolites and blood pressure in young adults: a pilot double-blind randomised crossover trial – CORRIGENDUM Open
[This corrects the article DOI: 10.1017/gmb.2025.10008.].
View article: The effects of inorganic nitrate and inulin co-ingestion on circulating metabolites and blood pressure in young adults: a pilot double-blind randomised crossover trial
The effects of inorganic nitrate and inulin co-ingestion on circulating metabolites and blood pressure in young adults: a pilot double-blind randomised crossover trial Open
Dietary patterns enriched in fermentable fibre (such as inulin) and inorganic nitrate are linked to cardiovascular benefits, possibly mediated by gut microbiota-derived bioactive compounds including short-chain fatty acids (SCFAs) and nitr…
View article: Oral microbiome and nitric oxide biomarkers in older people with mild cognitive impairment and <i>APOE4</i> genotype
Oral microbiome and nitric oxide biomarkers in older people with mild cognitive impairment and <i>APOE4</i> genotype Open
Apolipoprotein E4 (APOE4) genotype and nitric oxide (NO) deficiency are risk factors for age-associated cognitive decline. The oral microbiome plays a critical role in maintaining NO bioavailability during aging. The aim of this study was …
View article: Effects of low and high dietary nitrate intake on human saliva, plasma and skeletal muscle nitrate and nitrite concentrations and their functional consequences
Effects of low and high dietary nitrate intake on human saliva, plasma and skeletal muscle nitrate and nitrite concentrations and their functional consequences Open
Dietary nitrate (NO3-) supplementation has been shown to reduce blood pressure (BP), improve exercise performance, and alter the oral microbiome. Following a "control" diet (CON), we manipulated dietary NO3- intake to examine the effect of…
View article: New era for the European Journal of Sport Science: Moving to open access
New era for the European Journal of Sport Science: Moving to open access Open
It is an honour for us, as the editor-in-chief of the European Journal of Sport Science (EJSS) and the President of the European College of Sport Science (ECSS) to welcome readers to the very first fully Open Access issue of EJSS. This is …
View article: Localisation of nitrate-reducing and highly abundant microbial communities in the oral cavity
Localisation of nitrate-reducing and highly abundant microbial communities in the oral cavity Open
The nitrate (NO 3 - ) reducing bacteria resident in the oral cavity have been implicated as key mediators of nitric oxide (NO) homeostasis and human health. NO 3 - -reducing oral bacteria reduce inorganic dietary NO 3 - to nitrite (NO 2 - …
View article: Low Carbohydrate, High Fat Diet Alters the Oral Microbiome without Negating the Nitrite Response to Beetroot Juice Supplementation
Low Carbohydrate, High Fat Diet Alters the Oral Microbiome without Negating the Nitrite Response to Beetroot Juice Supplementation Open
A low carbohydrate, high fat (LCHF) diet in athletes increases fat oxidation but impairs sports performance, potentially due to impaired exercise economy. Dietary nitrate supplementation can improve exercise economy via an increase in nitr…
View article: <scp><sup>15</sup>N</scp>‐labeled dietary nitrate supplementation increases human skeletal muscle nitrate concentration and improves muscle torque production
<span><sup>15</sup>N</span>‐labeled dietary nitrate supplementation increases human skeletal muscle nitrate concentration and improves muscle torque production Open
Aim Dietary nitrate (NO 3 − ) supplementation increases nitric oxide bioavailability and can enhance exercise performance. We investigated the distribution and metabolic fate of ingested NO 3 − at rest and during exercise with a focus on s…
View article: Physiological and performance effects of dietary nitrate and N-acetylcysteine supplementation during prolonged heavy-intensity cycling
Physiological and performance effects of dietary nitrate and N-acetylcysteine supplementation during prolonged heavy-intensity cycling Open
The purpose of this study was to investigate effects of concurrent and independent administration of dietary nitrate (NO3-), administered as NO3--rich beetroot juice (BR; ~12.4 mmol of NO3-), and N-acetylcysteine (NAC; 70 mg·kg-1) on physi…
View article: Accounting for Dynamic Changes in the Power–Duration Relationship Improves the Accuracy of W′ Balance Modeling
Accounting for Dynamic Changes in the Power–Duration Relationship Improves the Accuracy of W′ Balance Modeling Open
Purpose This study aimed 1) to examine the accuracy with which W′ reconstitution (W′ REC ) is estimated by the W′ balance (W′ BAL ) models after a 3-min all-out cycling test (3MT), 2) to determine the effects of a 3MT on the power–duration…
View article: Effects of dietary nitrate on the O<sub>2</sub> cost of submaximal exercise: Accounting for “noise” in pulmonary gas exchange measurements
Effects of dietary nitrate on the O<sub>2</sub> cost of submaximal exercise: Accounting for “noise” in pulmonary gas exchange measurements Open
Dietary nitrate (NO3-) supplementation can reduce the oxygen cost of submaximal exercise, but this has not been reported consistently. We hypothesised that the number of step transitions to moderate-intensity exercise, and corresponding ef…
View article: Time course of human skeletal muscle nitrate and nitrite concentration changes following dietary nitrate ingestion
Time course of human skeletal muscle nitrate and nitrite concentration changes following dietary nitrate ingestion Open
Dietary nitrate (NO3-) ingestion can be beneficial for health and exercise performance. Recently, based on animal and limited human studies, a skeletal muscle NO3- reservoir has been suggested to be important in whole body nitric oxide (NO…
View article: Steady-state $$\dot{V}{\text{O}}_{2}$$ above MLSS: evidence that critical speed better represents maximal metabolic steady state in well-trained runners
Steady-state $$\dot{V}{\text{O}}_{2}$$ above MLSS: evidence that critical speed better represents maximal metabolic steady state in well-trained runners Open
The metabolic boundary separating the heavy-intensity and severe-intensity exercise domains is of scientific and practical interest but there is controversy concerning whether the maximal lactate steady state (MLSS) or critical power (syno…
View article: Network analysis of nitrate-sensitive oral microbiome reveals interactions with cognitive function and cardiovascular health across dietary interventions
Network analysis of nitrate-sensitive oral microbiome reveals interactions with cognitive function and cardiovascular health across dietary interventions Open
Many oral bacteria reduce inorganic nitrate, a natural part of a vegetable-rich diet, into nitrite that acts as a precursor to nitric oxide, a regulator of vascular tone and neurotransmission. Aging is hallmarked by reduced nitric oxide pr…
View article: Physiological demands of running at 2-hour marathon race pace
Physiological demands of running at 2-hour marathon race pace Open
We report the physiological characteristics and O 2 cost of running overground at ∼21.1 km/h in a cohort of the world’s best male distance runners. We provide new information on the absolute and relative O 2 uptake required to run at 2-h m…
View article: Vegetables with High-Nitrate Content Significantly Increase Plasma Nitrate and Nitrite Concentrations but Do Not Significantly Reduce Systolic Blood Pressure in Young Healthy Men
Vegetables with High-Nitrate Content Significantly Increase Plasma Nitrate and Nitrite Concentrations but Do Not Significantly Reduce Systolic Blood Pressure in Young Healthy Men Open
Aims: To investigate the effects of supplementation with high-nitrate and low-nitrate vegetables on plasma nitrate and nitrite concentrations, blood pressure and the oxygen demand of moderate-intensity exercise.
Study Design: A randomized…
View article: Response to considerations regarding Maximal Lactate Steady State determination before redefining the gold‐standard
Response to considerations regarding Maximal Lactate Steady State determination before redefining the gold‐standard Open
We reinforce the key messages in our earlier review paper that critical power, rather than maximal lactate steady state, provides the better index for defining steady-state vs non-steady state physiological behaviour during exercise.