Anthony Dellinger
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View article: Vitamin C as a Cardioprotective Agent Against Doxorubicin‐Induced Cardiotoxicity
Vitamin C as a Cardioprotective Agent Against Doxorubicin‐Induced Cardiotoxicity Open
Doxorubicin is used and highly effective chemotherapeutic agent; however, its clinical utility remains limited by dose‐dependent cardiotoxicity, presenting a significant challenge in cancer management. Growing preclinical research and clin…
View article: How Advanced are Self-Assembled Nanomaterials for Targeted Drug Delivery? A Comprehensive Review of the Literature
How Advanced are Self-Assembled Nanomaterials for Targeted Drug Delivery? A Comprehensive Review of the Literature Open
The development of effective drug delivery systems is a key focus in pharmaceutical research, aiming to enhance therapeutic efficacy while minimizing adverse effects. Self-assembled nanostructures present a promising solution due to their …
View article: Nanoscience systematic review methodology standardization
Nanoscience systematic review methodology standardization Open
The field of nanoscience has undergone significant transformations in the past two decades, presenting researchers with a complex and dynamic environment. Navigating the vast array of scholarly publications in nanoscience poses a formidabl…
View article: Enhanced thermal and structural properties of bacterial cellulose with MgAl <sub>2</sub> O <sub>4</sub> nanoparticles integration
Enhanced thermal and structural properties of bacterial cellulose with MgAl <sub>2</sub> O <sub>4</sub> nanoparticles integration Open
Bacterial cellulose (BC), a biogenic nanomaterial with a three-dimensional reticulated architecture, serves as a dynamic platform for next-generation composites.
View article: A Natural Serotonin Stimulant for Appetite Suppression and Targeted Eating as an Alternative to Conventional Obesity Treatments
A Natural Serotonin Stimulant for Appetite Suppression and Targeted Eating as an Alternative to Conventional Obesity Treatments Open
Recent advances in obesity management reflect the integration of pharmacological, surgical, and behavioral interventions, yet sustainable long-term outcomes remain elusive due to high attrition rates, the complexity of protocol compliance …
View article: A rapid one-step synthesis of silver and copper coordinated chlorine functionalized fullerene nanoparticles with enhanced antibacterial activity
A rapid one-step synthesis of silver and copper coordinated chlorine functionalized fullerene nanoparticles with enhanced antibacterial activity Open
Methods of chemical characterization and antibacterial studies for silver- and copper-coordinated chloro-fullerenes nanoparticles.
View article: Human Tumor Targeted Cytotoxic Mast Cells for Cancer Immunotherapy
Human Tumor Targeted Cytotoxic Mast Cells for Cancer Immunotherapy Open
The diversity of autologous cells being used and investigated for cancer therapy continues to increase. Mast cells (MCs) are tissue cells that contain a unique set of anti-cancer mediators and are found in and around tumors. We sought to e…
View article: Human Tumor Targeted Cytotoxic Mast Cells for Cancer Immunotherapy
Human Tumor Targeted Cytotoxic Mast Cells for Cancer Immunotherapy Open
The diversity of autologous cells being used and investigated for cancer therapy continues to increase. Mast cells (MCs) are tissue cells that contain a unique set of anti-cancer mediators and are found in and around tumors. We sought to e…
View article: Effects of Diet on the Biochemical Properties of Limulus Amebocyte Lysate From Horseshoe Crabs in an Aquaculture Setting
Effects of Diet on the Biochemical Properties of Limulus Amebocyte Lysate From Horseshoe Crabs in an Aquaculture Setting Open
The Limulus amebocyte lysate (LAL) isolated from cells in the horseshoe crab (HSC) hemolymph is a critical resource for global biomedical and pharmaceutical quality control and sterility testing. Given the necessity of and limitations asso…
View article: Evaluation of Indoor and Outdoor Aquaculture Systems as Alternatives to Harvesting Hemolymph From Random Wild Capture of Horseshoe Crabs
Evaluation of Indoor and Outdoor Aquaculture Systems as Alternatives to Harvesting Hemolymph From Random Wild Capture of Horseshoe Crabs Open
This study evaluated two approaches to the aquaculture of Limulus polyphemus with the ultimate goal of harvesting Limulus amebocyte lysate (LAL) at an industrial scale. To monitor Horseshoe crabs (HSCs), a combination of physical, biochemi…
View article: Horseshoe Crab Aquaculture as a Sustainable Endotoxin Testing Source
Horseshoe Crab Aquaculture as a Sustainable Endotoxin Testing Source Open
Horseshoe crab (HSC) hemolymph is the source of Limulus amebocyte lysate (LAL), a critical component in sterility testing that ensures drug and medical device safety for millions of patients every year. Wild HSC populations have been decli…
View article: Design and Testing of Dual-Targeted Gd<sub>3</sub>N@C80-Containing Glioblastoma Theranostics
Design and Testing of Dual-Targeted Gd<sub>3</sub>N@C80-Containing Glioblastoma Theranostics Open
The majority of the malignant brain tumors are gliomas with glioblastoma being the most common and aggressive type. Due to its extreme infiltrative nature and higher occurrence frequency, finding new glioblastoma therapeutics and diagnosti…
View article: Human Mast Cells From Adipose Tissue Target and Induce Apoptosis of Breast Cancer Cells
Human Mast Cells From Adipose Tissue Target and Induce Apoptosis of Breast Cancer Cells Open
Mast cells (MC) are important immune sentinels found in most tissue and widely recognized for their role as mediators of Type I hypersensitivity. However, they also secrete anti-cancer mediators such as tumor necrosis factor alpha (TNF-α) …
View article: The Role of Horseshoe Crabs in the Biomedical Industry and Recent Trends Impacting Species Sustainability
The Role of Horseshoe Crabs in the Biomedical Industry and Recent Trends Impacting Species Sustainability Open
Every year the Atlantic horseshoe crab (Limulus polyphemus) arrives on shore to spawn, a sight once taken for granted. However, in addition to the gradual climate changes impacting all ecosystems, commercial demand from the widespread appl…
View article: A synthetic crustacean bait to stem forage fish depletion
A synthetic crustacean bait to stem forage fish depletion Open
Crustaceans, such as crab and lobster, comprise an important global food commodity. They are captured in traps using primarily forage fish (e.g. anchovies, herring, and menhaden), as bait. Approximately 18 million tons of these fish are us…
View article: Inhibition of Inflammatory Arthritis Using Fullerene Nanomaterials
Inhibition of Inflammatory Arthritis Using Fullerene Nanomaterials Open
Inflammatory arthritis (e.g. rheumatoid arthritis; RA) is a complex disease driven by the interplay of multiple cellular lineages. Fullerene derivatives have previously been shown to have anti-inflammatory capabilities mediated, in part, b…