Anton Lund
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View article: Influence of Obesity and IL-6 on Human Postprandial Amino Acid and Protein Metabolism at Whole-body and Tissue Level
Influence of Obesity and IL-6 on Human Postprandial Amino Acid and Protein Metabolism at Whole-body and Tissue Level Open
Context Sarcopenic obesity, the loss of muscle mass and function in people with obesity, may result from altered muscle protein synthesis and degradation. Chronic low-grade inflammation, particularly IL-6, has been implicated. Objective To…
View article: Relationship Between Systemic and Cerebral Microdialysate Glucose in Patients With Severe Acute Brain Injury—A Retrospective Study
Relationship Between Systemic and Cerebral Microdialysate Glucose in Patients With Severe Acute Brain Injury—A Retrospective Study Open
Background Markers of cerebral metabolism measured by microdialysis (CMD) may warn clinicians of impending neuroworsening in patients with severe acute brain injury. This retrospective study investigated the relationship between systemic g…
View article: Inhibition of basal IL-6 activity promotes subcutaneous fat retention in humans during fasting and postprandial states
Inhibition of basal IL-6 activity promotes subcutaneous fat retention in humans during fasting and postprandial states Open
Interleukin-6 (IL-6) knockout mice and humans treated with IL-6 receptor blockade gain adipose tissue mass. This study investigates whether basal IL-6 activity (resting IL-6 levels) influences fat storage during fasting and postprandial st…
View article: Brain hypoxia and metabolic crisis are common in patients with acute brain injury despite a normal intracranial pressure
Brain hypoxia and metabolic crisis are common in patients with acute brain injury despite a normal intracranial pressure Open
Patients with acute brain injury are vulnerable to secondary deterioration, which may go undetected by traditional monitoring. However, multimodal neuromonitoring of brain tissue oxygen tension (PbtO 2 ) and energy metabolism may be able t…
View article: Near‐infrared spectroscopy to measure brain oxygenation: A comparison of measurements on the skin, skull and dura mater
Near‐infrared spectroscopy to measure brain oxygenation: A comparison of measurements on the skin, skull and dura mater Open
Background The reliability of near‐infrared spectroscopy (NIRS) for measuring cerebral oxygenation (ScO 2 ) is controversial due to the possible contamination from extracranial tissues. We compared ScO 2 measured with the NIRS optode on th…
View article: Impact of hyperoxia and phenylephrine on cerebral oxygenation: An experimental clinical study
Impact of hyperoxia and phenylephrine on cerebral oxygenation: An experimental clinical study Open
Background Oxygen supply to the brain is of special importance during intracranial surgery because it may be compromised by intracranial pathology. A high arterial blood pressure (mean arterial pressure above 80 mmHg) and a high arterial o…
View article: SP230INTRACRANIAL PRESSURE DURING HEMODIALYSIS IN PATIENTS WITH ACUTE BRAIN INJURY
SP230INTRACRANIAL PRESSURE DURING HEMODIALYSIS IN PATIENTS WITH ACUTE BRAIN INJURY Open
INTRODUCTION AND AIMS: Osmotic changes during hemodialysis have been reported to cause development of cerebral edema and intracranial hypertension in some patients.Patients with pre-existing acute brain injury are likely at increased risk.…
View article: Increased Intracranial Pressure during Hemodialysis in a Patient with Anoxic Brain Injury
Increased Intracranial Pressure during Hemodialysis in a Patient with Anoxic Brain Injury Open
Dialysis disequilibrium syndrome (DDS) is a serious neurological complication of hemodialysis, and patients with acute brain injury are at increased risk. We report a case of DDS leading to intracranial hypertension in a patient with anoxi…