Anton Pashkov
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View article: A large-scale dataset of pre- and postsurgical MRI data from patients with chronic trigeminal neuralgia
A large-scale dataset of pre- and postsurgical MRI data from patients with chronic trigeminal neuralgia Open
The study of chronic pain is a priority in contemporary medical science because of its significant social importance. In this article, we present a large dataset of neuroimaging data from patients with chronic trigeminal neuralgia (112 pat…
View article: Reorganization of brain networks in olfactory groove meningioma patients: a pilot resting-state fMRI study
Reorganization of brain networks in olfactory groove meningioma patients: a pilot resting-state fMRI study Open
Background Olfactory groove meningioma (OGM) is frequently associated with neuropsychological and behavioral impairments. However, there is currently a lack of evidence on the pathobiology of these functional alterations. In this study, ou…
View article: Hybrid de novo genome assembly data and comparative genomics of Fusarium chlamydosporum isolated from infected blackberry fields
Hybrid de novo genome assembly data and comparative genomics of Fusarium chlamydosporum isolated from infected blackberry fields Open
Here, we present a dataset of ITS and β-tubulin sequences, along with a phylogenetic analysis using these molecular markers, for six putative Fusarium strains isolated from blackberry field soil. Additionally, we report the sequencing and …
View article: Cognitive and Personality Profiles of Patients With Chronic Trigeminal Neuralgia
Cognitive and Personality Profiles of Patients With Chronic Trigeminal Neuralgia Open
Background Patients suffering from chronic pain are known to exhibit distinctive personality traits and impaired neuropsychological performance across various cognitive domains. However, there is currently a lack of comprehensive evidence …
View article: Assessment of Trigeminal Nerve Root Demyelination in Patients with Primary Trigeminal Neuralgia Using Macromolecular Proton Fraction Imaging
Assessment of Trigeminal Nerve Root Demyelination in Patients with Primary Trigeminal Neuralgia Using Macromolecular Proton Fraction Imaging Open
Our preliminary results suggest that MPF could serve as a new neuroimaging biomarker of trigeminal nerve root impairment in patients with PTN and enable noninvasive detection of nerve root demyelination.
View article: Direct comparison of EEG resting state and task functional connectivity patterns for predicting working memory performance using connectome-based predictive modeling
Direct comparison of EEG resting state and task functional connectivity patterns for predicting working memory performance using connectome-based predictive modeling Open
The use of machine learning techniques combined with advanced neuroimaging methods to reveal a complex relationship between patterns of neuronal activity and behavioral characteristics is an actively developing area in modern neuroscience.…
View article: EEG connectome-based predictive modeling of nonverbal intelligence level in healthy subjects
EEG connectome-based predictive modeling of nonverbal intelligence level in healthy subjects Open
Intelligence is increasingly recognized as a critical factor in successful behavioral and emotional regulation. Neuroimaging techniques coupled with machine learning algorithms have proven to be valuable tools for uncovering the neural fou…
View article: Neuropsychological and behavioral profiles of patients with chronic trigeminal neuralgia
Neuropsychological and behavioral profiles of patients with chronic trigeminal neuralgia Open
Patients suffering from chronic pain are known to exhibit distinctive personality traits and impaired neuropsychological performance across various cognitive domains. However, there is currently a lack of comprehensive evidence regarding c…
View article: Unraveling the Serotonergic Mechanism of Stress-Related Anxiety: Focus on Co-Treatment with Resveratrol and Selective Serotonin Reuptake Inhibitors
Unraveling the Serotonergic Mechanism of Stress-Related Anxiety: Focus on Co-Treatment with Resveratrol and Selective Serotonin Reuptake Inhibitors Open
Background/Objectives: In post-traumatic stress disorder (PTSD), anxiety-like symptoms are often associated with elevated noradrenaline levels and decreased serotonin. Selective serotonin reuptake inhibitors (SSRIs) are frequently used to …
View article: Unraveling the Liver–Brain Axis: Resveratrol’s Modulation of Key Enzymes in Stress-Related Anxiety
Unraveling the Liver–Brain Axis: Resveratrol’s Modulation of Key Enzymes in Stress-Related Anxiety Open
Stress-related anxiety disorders and anxiety-like behavior in post-traumatic stress disorder (PTSD) are associated with altered neurocircuitry pathways, neurotransmitter systems, and the activities of monoamine and glucocorticoid-metaboliz…
View article: Large language models surpass human experts in predicting neuroscience results
Large language models surpass human experts in predicting neuroscience results Open
Scientific discoveries often hinge on synthesizing decades of research, a task that potentially outstrips human information processing capacities. Large language models (LLMs) offer a solution. LLMs trained on the vast scientific literatur…
View article: Meeting the challenge of genomic analysis: a collaboratively developed workshop for pangenomics and topological data analysis
Meeting the challenge of genomic analysis: a collaboratively developed workshop for pangenomics and topological data analysis Open
Motivation As genomics data analysis becomes increasingly intricate, researchers face the challenge of mastering various software tools. The rise of Pangenomics analysis, which examines the complete set of genes in a group of genomes, is p…
View article: Thalamic nuclei in patients with chronic facial pain: gray matter volume patterns before and after surgery
Thalamic nuclei in patients with chronic facial pain: gray matter volume patterns before and after surgery Open
Trigeminal neuralgia is a prevalent chronic pain disorder characterized by recurring episodes of intense facial pain, which significantly impairs patients’ quality of life. MRI-based biomarkers have consistently demonstrated their ability …
View article: Automating Stimulation Frequency Selection for SSVEP-Based Brain-Computer Interfaces
Automating Stimulation Frequency Selection for SSVEP-Based Brain-Computer Interfaces Open
Brain–computer interfaces (BCIs) based on steady-state visually evoked potentials (SSVEPs) are inexpensive and do not require user training. However, the highly personalized reaction to visual stimulation is an obstacle to the wider applic…
View article: Limited Cheese Intake Paradigm Replaces Patterns of Behavioral Disorders in Experimental PTSD: Focus on Resveratrol Supplementation
Limited Cheese Intake Paradigm Replaces Patterns of Behavioral Disorders in Experimental PTSD: Focus on Resveratrol Supplementation Open
Currently, the efficacy of drug therapy for post-traumatic stress disorder or PTSD leaves much to be desired, making nutraceutical support a promising avenue for treatment. Recent research has identified the protective effects of resveratr…
View article: Profile of speech and cognitive impairments in a patient with moyamoya disease: a longitudinal case study
Profile of speech and cognitive impairments in a patient with moyamoya disease: a longitudinal case study Open
Moyamoya is a rare chronic brain vascular disease with a set of potential life-threatening consequences due to a high probability of stroke occurrence. Patients suffering from this disease are often presented with diverse and severe sensor…
View article: Utilizing the Amide Proton Transfer Technique to Characterize Diffuse Gliomas Based on the WHO 2021 Classification of CNS Tumors
Utilizing the Amide Proton Transfer Technique to Characterize Diffuse Gliomas Based on the WHO 2021 Classification of CNS Tumors Open
Purpose Diffuse gliomas present a significant challenge for healthcare systems globally. While brain MRI plays a vital role in diagnosis, prognosis, and treatment monitoring, accurately characterizing gliomas using conventional MRI techniq…
View article: Unveiling the Link: Exploring Mitochondrial Dysfunction as a Probable Mechanism of Hepatic Damage in Post-Traumatic Stress Syndrome
Unveiling the Link: Exploring Mitochondrial Dysfunction as a Probable Mechanism of Hepatic Damage in Post-Traumatic Stress Syndrome Open
PTSD is associated with disturbed hepatic morphology and metabolism. Neuronal mitochondrial dysfunction is considered a subcellular determinant of PTSD, but a link between hepatic mitochondrial dysfunction and hepatic damage in PTSD has no…
View article: Brain but not serum BDNF levels are associated with structural alterations in the hippocampal regions in patients with drug-resistant mesial temporal lobe epilepsy
Brain but not serum BDNF levels are associated with structural alterations in the hippocampal regions in patients with drug-resistant mesial temporal lobe epilepsy Open
Mesial temporal lobe epilepsy is the most common type of focal epilepsy, imposing a significant burden on the health care system worldwide. Approximately one-third of patients with this disease who do not adequately respond to pharmacother…
View article: White and Gray Matter Perfusion in Children with Moyamoya Angiopathy after Revascularization Surgery
White and Gray Matter Perfusion in Children with Moyamoya Angiopathy after Revascularization Surgery Open
Introduction: Surgical revascularization is very effective in patients with moyamoya angiopathy (MMA) and leads to improvements in cortical perfusion parameters. However, changes in white matter hemodynamics are still underestimated. To da…
View article: Supplementary Material for: White and grey matter perfusion in children with moyamoya angiopathy after revascularization surgery
Supplementary Material for: White and grey matter perfusion in children with moyamoya angiopathy after revascularization surgery Open
Introduction: Surgical revascularization is very effective in patients with moyamoya angiopathy (MMA) and leads to improvements in cortical perfusion parameters. However, changes in white matter hemodynamics are still underestimated. To da…
View article: Cerebral Blood Flow in Predator Stress-Resilient and -Susceptible Rats and Mechanisms of Resilience
Cerebral Blood Flow in Predator Stress-Resilient and -Susceptible Rats and Mechanisms of Resilience Open
Stress-induced conditions are associated with impaired cerebral blood flow (CBF) and increased risk of dementia and stroke. However, these conditions do not develop in resilient humans and animals. Here the effects of predator stress (PS, …
View article: Mechanisms of Susceptibility and Resilience to PTSD: Role of Dopamine Metabolism and BDNF Expression in the Hippocampus
Mechanisms of Susceptibility and Resilience to PTSD: Role of Dopamine Metabolism and BDNF Expression in the Hippocampus Open
Susceptibility and resilience to post-traumatic stress disorder (PTSD) are recognized, but their mechanisms are not understood. Here, the hexobarbital sleep test (HST) was used to elucidate mechanisms of PTSD resilience or susceptibility. …
View article: Paradoxical Anxiety Level Reduction in Animal Chronic Stress: A Unique Role of Hippocampus Neurobiology
Paradoxical Anxiety Level Reduction in Animal Chronic Stress: A Unique Role of Hippocampus Neurobiology Open
A paradoxical reduction in anxiety levels in chronic predator stress paradigm (PS) in Sprague–Dawley rats has recently been shown in previous works. In this paper, we studied the possible neurobiological mechanism of this phenomenon. We se…
View article: The Link between Activities of Hepatic 11beta-Hydroxysteroid Dehydrogenase-1 and Monoamine Oxidase-A in the Brain Following Repeated Predator Stress: Focus on Heightened Anxiety
The Link between Activities of Hepatic 11beta-Hydroxysteroid Dehydrogenase-1 and Monoamine Oxidase-A in the Brain Following Repeated Predator Stress: Focus on Heightened Anxiety Open
We investigated the presence of a molecular pathway from hepatic 11-βHSD-1 to brain MAO-A in the dynamics of plasma corticosterone involvement in anxiety development. During 14 days following repeated exposure of rats to predator scent str…
View article: A Rat Model of Post-Traumatic Stress Syndrome Causes Phenotype-Associated Morphological Changes and Hypofunction of the Adrenal Gland
A Rat Model of Post-Traumatic Stress Syndrome Causes Phenotype-Associated Morphological Changes and Hypofunction of the Adrenal Gland Open
Background: Rats exposed to chronic predator scent stress mimic the phenotype of complex post-traumatic stress disorder (PTSD) in humans, including altered adrenal morphology and function. High- and low-anxiety phenotypes have been describ…
View article: Computational psychiatry 2.0 and implications for stress research
Computational psychiatry 2.0 and implications for stress research Open
Stress-related disorders are highly prevalent in modern society and pose significant challenge to human’s health. Being recently emerged branch of psychiatry, computational psychiatry is geared toward mathematical modeling of psychiatric d…