Antonello D’Andrea
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View article: Takotsubo Syndrome and Cancer: Pathophysiological Links and Clinical Perspectives
Takotsubo Syndrome and Cancer: Pathophysiological Links and Clinical Perspectives Open
Takotsubo syndrome (TTS) is an acute, reversible cardiomyopathy that clinically mimics acute coronary syndrome in the absence of obstructive coronary artery disease. In oncology, TTS may be precipitated by the cancer milieu itself (stress,…
View article: Optimum Patient’s Selection for Atrial Fibrillation Ablation Using Echocardiography
Optimum Patient’s Selection for Atrial Fibrillation Ablation Using Echocardiography Open
Catheter ablation (CA) has become a validated technique for treating patients with symptomatic or paroxysmal atrial fibrillation (AF), as recommended by the latest 2024 European society of cardiology (ESC) guidelines, class II level A. The…
View article: Echocardiographic monitoring in cancer therapy: clinical guidance for cardiologists and oncologists
Echocardiographic monitoring in cancer therapy: clinical guidance for cardiologists and oncologists Open
Transthoracic echocardiography has a central role in the diagnosis and monitoring of cancer therapy-related cardiac dysfunction, offering a reliable, non-invasive, and cost-effective tool for the early detection of myocardial damage and th…
View article: Atrial Septal Defect and Heart Rhythm Disorders: Physiopathological Linkage and Clinical Perspectives
Atrial Septal Defect and Heart Rhythm Disorders: Physiopathological Linkage and Clinical Perspectives Open
An atrial septal defect (ASD) is the most common congenital heart defect (CHD) diagnosed in adulthood. It is characterized by significant anatomical heterogeneity and complications that evolve over time. While often asymptomatic in childre…
View article: The Crucial Role of Tinzaparin in Managing Venous Thromboembolism in the Cancer Population
The Crucial Role of Tinzaparin in Managing Venous Thromboembolism in the Cancer Population Open
Background: Venous thromboembolism (VTE) is a serious and common complication in cancer patients, and it is the second leading cause of death after cancer itself. Cancer-associated thrombosis (CAT) is an indicator of a poorer prognosis and…
View article: Atrial Fibrillation and Cancer: Pathophysiological Mechanism and Clinical Implications
Atrial Fibrillation and Cancer: Pathophysiological Mechanism and Clinical Implications Open
Atrial fibrillation is the most frequent arrhythmia in elderly subjects. Cancer currently represents one of the most important causes of mortality and morbidity in the world. Often, the two pathologies coexist. Several pathophysiological m…
View article: Heart Failure and Wide QRS: Clinical and Pharmacological Perspectives
Heart Failure and Wide QRS: Clinical and Pharmacological Perspectives Open
Heart failure (HF) is a highly prevalent cardiovascular clinical syndrome. Health care spending on HF treatment is high. Therefore, its treatment has generated a great deal of interest in pharmacological research in recent years. Recent gu…
View article: Migration of an Implantable Loop Recorder: A Meta-summary of Case Reports
Migration of an Implantable Loop Recorder: A Meta-summary of Case Reports Open
The migration of an implantable loop recorder (ILR) is a rare complication. We aimed to perform a meta-summary of case reports to characterize patients who experienced an ILR migration. We searched for case reports published in PubMed, Goo…
View article: Takotsubo Syndrome and Oxidative Stress: Physiopathological Linkage and Future Perspectives
Takotsubo Syndrome and Oxidative Stress: Physiopathological Linkage and Future Perspectives Open
Takotsubo syndrome (TTS) is an acute coronary syndrome of unknown prevalence with a physiopathological mechanism that is not yet fully understood. The course is generally benign. Current therapeutic management is based on limited evidence.…
View article: Epigenetic mechanisms underlying the beneficial effects of cardiac rehabilitation. An overview from the working groups of “cellular and molecular biology of the heart” and “cardiac rehabilitation and cardiovascular prevention” of the Italian Society of Cardiology (SIC)
Epigenetic mechanisms underlying the beneficial effects of cardiac rehabilitation. An overview from the working groups of “cellular and molecular biology of the heart” and “cardiac rehabilitation and cardiovascular prevention” of the Italian Society of Cardiology (SIC) Open
The benefits of cardiac rehabilitation (CR) have been demonstrated in patients after myocardial infarction (MI), and in patients with chronic heart failure (HF). The core components of the CR program include improvement in exercise toleran…
View article: Serum Lipids, Inflammation, and the Risk of Atrial Fibrillation: Pathophysiological Links and Clinical Evidence
Serum Lipids, Inflammation, and the Risk of Atrial Fibrillation: Pathophysiological Links and Clinical Evidence Open
Dyslipidemia is a metabolic disorder characterized by quantitative and/or qualitative abnormalities in serum lipid levels. Elevated serum cholesterol levels can modify the turnover and recruitment of ionic channels in myocytes and cellular…
View article: How to Do Echo for Noninvasive Hemodynamic Evaluation of the Patient in the Intensive Care Unit: A Consensus Statement of the Italian Society of Echocardiography and Cardiovascular Imaging
How to Do Echo for Noninvasive Hemodynamic Evaluation of the Patient in the Intensive Care Unit: A Consensus Statement of the Italian Society of Echocardiography and Cardiovascular Imaging Open
Critically ill patients in the intensive care unit (ICU) require continuous hemodynamic monitoring to guide therapeutic decisions and prevent clinical deterioration. Echocardiography has emerged as a cornerstone for noninvasive hemodynamic…
View article: Echocardiography in the Ventilated Patient: What the Clinician Has to Know
Echocardiography in the Ventilated Patient: What the Clinician Has to Know Open
Heart and lung sharing the same anatomical space are influenced by each other. Spontaneous breathing induces dynamic changes in intrathoracic pressure, impacting cardiac function, particularly the right ventricle. In intensive care units (…
View article: Relationship Between Left Atrial Strain and Atrial Fibrillation: The Role of Stress Echocardiography
Relationship Between Left Atrial Strain and Atrial Fibrillation: The Role of Stress Echocardiography Open
Interest in advanced echocardiographic imaging methods is growing. Left atrial strain (LAS) is among recently developed echocardiographic parameters. LAS represents an index of tissue deformation of the left atrium (LA). This parameter is …
View article: Relationship Between Left Atrial Strain and Atrial Fibrillation: The Role of Stress Echocardiography
Relationship Between Left Atrial Strain and Atrial Fibrillation: The Role of Stress Echocardiography Open
Interest in advanced echocardiographic imaging methods is growing. The left atrial strain (LAS) is among the recently developed echocardiographic parameters. LAS represents an index of tissue deformation of the left atrium (LA). This param…
View article: Mitochondrial Dysfunction in Atrial Fibrillation: The Need for a Strong Pharmacological Approach
Mitochondrial Dysfunction in Atrial Fibrillation: The Need for a Strong Pharmacological Approach Open
Despite great progress in treating atrial fibrillation (AF), especially with the development of increasingly effective invasive techniques for AF ablation, many unanswered questions remain regarding the pathogenic mechanism of the arrhythm…
View article: Exercise Echocardiography of Left Ventricular Diastolic Function in Healthy Subjects: Insights From the RIGHT-NET
Exercise Echocardiography of Left Ventricular Diastolic Function in Healthy Subjects: Insights From the RIGHT-NET Open
In healthy adult subjects, E/e' slightly increased during midlevel exercise. Both E/e' and TRV are exercise intensity-dependent and would therefore be better expressed as a function of CO for the diagnosis of normal vs abnormal LV diastoli…
View article: Mitochondrial Dysfunction in Atrial Fibrillation: Needs Strong Pharmacological Approach
Mitochondrial Dysfunction in Atrial Fibrillation: Needs Strong Pharmacological Approach Open
Despite great progress in the treatment of atrial fibrillation (AF), especially with the development of increasingly effective invasive techniques, many questions remain unanswered regarding the pathogenic mechanism of the arrhythmia and i…
View article: Left atrial function during exercise stress echocardiography as a sign of paroxysmal/persistent atrial fibrillation
Left atrial function during exercise stress echocardiography as a sign of paroxysmal/persistent atrial fibrillation Open
View article: Italian Cardiological Guidelines (COCIS) for Competitive Sport Eligibility in athletes with heart disease: update 2024
Italian Cardiological Guidelines (COCIS) for Competitive Sport Eligibility in athletes with heart disease: update 2024 Open
Nearly 35 years after its initial publication in 1989, the Italian Society of Sports Cardiology and the Italian Federation of Sports Medicine (FMSI), in collaboration with other leading Italian Cardiological Scientific Associations (ANCE -…
View article: Echocardiography in Cardiac Arrest: Incremental Diagnostic and Prognostic Role during Resuscitation Care
Echocardiography in Cardiac Arrest: Incremental Diagnostic and Prognostic Role during Resuscitation Care Open
Background: Cardiac arrest (CA) is a life-critical condition. Patients who survive after CA go into a defined post-cardiac arrest syndrome (PCAS). In this clinical context, the role of the echocardiogram in recent years has become increasi…
View article: Echocardiography in Cardiac Arrest: Incremental Diagnostic and Prognostic Role during Resuscitation Care
Echocardiography in Cardiac Arrest: Incremental Diagnostic and Prognostic Role during Resuscitation Care Open
Cardiac arrest (CA) is a life-critical condition. Patients who survive after CA, they go into a defined post-cardiac arrest syndrome (PCAS). In this clinical context, the role of the echocardiogram in recent years has become increasingly i…
View article: Stress echocardiography in heart failure patients: additive value and caveats
Stress echocardiography in heart failure patients: additive value and caveats Open
View article: Aortic Regurgitation in Bicuspid Aortic Valve: The Role of Multimodality Imaging
Aortic Regurgitation in Bicuspid Aortic Valve: The Role of Multimodality Imaging Open
The evaluation of aortic regurgitation (AR) in bicuspid valve (BAV) is still a challenge because of the eccentricity of the jet, which may under/overestimate the regurgitation. The commonly used echocardiography parameters (such as vena co…
View article: Effects of Heart Failure Therapies on Atrial Fibrillation: Biological and Clinical Perspectives
Effects of Heart Failure Therapies on Atrial Fibrillation: Biological and Clinical Perspectives Open
Heart failure (HF) and atrial fibrillation (AF) are prevalent cardiovascular diseases that contribute significantly to morbidity, mortality, hospitalisation, and healthcare costs. It is not uncommon for these conditions to coexist and have…
View article: Predictors of hypercontractile heart phenotype in patients with chronic coronary syndromes or heart failure
Predictors of hypercontractile heart phenotype in patients with chronic coronary syndromes or heart failure Open
Background Hypercontractile phenotype (HP) of the left ventricle (LV) is an actionable therapeutic target in patients with chronic coronary syndromes (CCS) or heart failure (HF), but its clinical recognition remains difficult. Objectives T…
View article: The role of echocardiography in sports cardiology: An expert opinion statement of the Italian Society of Sports Cardiology (SIC sport)
The role of echocardiography in sports cardiology: An expert opinion statement of the Italian Society of Sports Cardiology (SIC sport) Open
View article: IMPROVEMENT OF GLOBAL LONGITUDINAL STRAIN AND MYOCARDIAL WORK IN TYPE 2 DIABETES PATIENTS ON SODIUM–GLUCOSE COTRANSPORTER 2 INHIBITORS THERAPY
IMPROVEMENT OF GLOBAL LONGITUDINAL STRAIN AND MYOCARDIAL WORK IN TYPE 2 DIABETES PATIENTS ON SODIUM–GLUCOSE COTRANSPORTER 2 INHIBITORS THERAPY Open
Introduction Sodium–glucose cotransporter 2 inhibitors (SGLT2–i) are a novel class of oral hypoglycaemic agents currently used among patients with type 2 diabetes mellitus (T2DM). The effects of SGLT2–i inhibitors on cardiac structure and …
View article: A CHALLENGING CASE OF PERCUTANEOUS ATRIAL SEPTAL DEFECT CLOSURE
A CHALLENGING CASE OF PERCUTANEOUS ATRIAL SEPTAL DEFECT CLOSURE Open
ASDs account for 13% of all congenital heart diagnoses at birth but remain asymptomatic until adulthood, when atrial arrhythmias, paradoxical embolization or pulmonary hypertension can develop. A 46–year–old woman, without significant card…
View article: The Lipid-Lowering Efficacy of a Nutraceutical Combination Including Leucoselect Phytosome, Red Yeast Rice, Policosanol and Folic Acid in Dyslipidaemia Patients: Real-World Insights
The Lipid-Lowering Efficacy of a Nutraceutical Combination Including Leucoselect Phytosome, Red Yeast Rice, Policosanol and Folic Acid in Dyslipidaemia Patients: Real-World Insights Open
Background: Cardiovascular disease is a global health concern and reducing plasma LDL-C levels is a major goal in cardiovascular prevention. Our study aimed to evaluate the effectiveness of a nutraceutical formulation including leucoselect…