Antonija Tomić
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View article: KEAP1-NRF2 Interaction in Cancer: Competitive Interactors and Their Role in Carcinogenesis
KEAP1-NRF2 Interaction in Cancer: Competitive Interactors and Their Role in Carcinogenesis Open
An American Cancer Society report estimates the emergence of around 2 million new cancer cases in the US in 2024 [...]
View article: Utjecaj temperature maceracije na polifenolni sastav vina sorte ‘Plavac mali crni’ (Vitis vinifera L.)
Utjecaj temperature maceracije na polifenolni sastav vina sorte ‘Plavac mali crni’ (Vitis vinifera L.) Open
’Plavac mali crni’ gospodarski je najvažnija crna sorta vinove loze na području RH. Tehnologija prerade grožđa ima značajan utjecaj na polifenolni sastav mošta, odnosno budućegvina. Klasični način prerade podrazumijeva istovremeno protjeca…
View article: Kemijski sastav hrvatskih voćnih vina kupine, aronije i višnje
Kemijski sastav hrvatskih voćnih vina kupine, aronije i višnje Open
Voćna vina, osim što obogaćuju ponudu pića na tržištu, čine i vrijedan prehrambeni izvor minerala, antioksidansa i fitonutrijenata, posebice polifenolnih spojeva. Vrijednost polifenolnih spojeva očituje se, ne samo utjecajem na senzorna sv…
View article: Pristine and UV-Weathered PET Microplastics as Water Contaminants: Appraising the Potential of the Fenton Process for Effective Remediation
Pristine and UV-Weathered PET Microplastics as Water Contaminants: Appraising the Potential of the Fenton Process for Effective Remediation Open
Polyethylene terephthalate (PET) microplastics constitute a significant portion of plastic pollution in the environment and pose substantial environmental challenges. In this study, the effectiveness of the Fenton process and post-oxidatio…
View article: Let’s Talk about Sex Hormone Receptors and Their Physical Interaction with Sonic Hedgehog Protein: A Computational Study with Emphasis on Progesterone Receptor
Let’s Talk about Sex Hormone Receptors and Their Physical Interaction with Sonic Hedgehog Protein: A Computational Study with Emphasis on Progesterone Receptor Open
The mature form of the sonic hedgehog protein (SHH-N) is the main canonical activator of the Hedgehog-GLI signaling pathway whose aberrant activity can lead to the development of hormone-dependent cancers like breast or prostate cancer. In…
View article: Structural Features Promoting Photocatalytic Degradation of Contaminants of Emerging Concern: Insights into Degradation Mechanism Employing QSA/PR Modeling
Structural Features Promoting Photocatalytic Degradation of Contaminants of Emerging Concern: Insights into Degradation Mechanism Employing QSA/PR Modeling Open
Although heterogeneous photocatalysis has shown promising results in degradation of contaminants of emerging concern (CECs), the mechanistic implications related to structural diversity of chemicals, affecting oxidative (by HO•) or reducti…
View article: Influence of Mutations of Conserved Arginines on Neuropeptide Binding in the DPP III Active Site
Influence of Mutations of Conserved Arginines on Neuropeptide Binding in the DPP III Active Site Open
Dipeptidyl peptidase III (DPP III), a zinc exopeptidase, is involved in the final steps of intercellular protein degradation and has a marked affinity for opioid peptides such as enkephalins and endomorphins. Recently, we characterized a n…
View article: Demystifying DPP III Catalyzed Peptide Hydrolysis—Computational Study of the Complete Catalytic Cycle of Human DPP III Catalyzed Tynorphin Hydrolysis
Demystifying DPP III Catalyzed Peptide Hydrolysis—Computational Study of the Complete Catalytic Cycle of Human DPP III Catalyzed Tynorphin Hydrolysis Open
Dipeptidyl peptides III (DPP III) is a dual-domain zinc exopeptidase that hydrolyzes peptides of varying sequence and size. Despite attempts to elucidate and narrow down the broad substrate-specificity of DPP III, there is no explanation a…
View article: Utjecaj različitih rokova defolijacije na kemijski sastav grožđa sorte Graševina u uvjetima vinogorja Slavonski Brod
Utjecaj različitih rokova defolijacije na kemijski sastav grožđa sorte Graševina u uvjetima vinogorja Slavonski Brod Open
Defolijacija je jedan od zahvata zelene rezidbe tijekom kojeg se vrši prorjeđivanje ili potpuno uklanjanje lisne mase u zoni grožđa. Ako se djelomična defolijacija provodi u fenofazi cvatnje vinove loze smatra se ranom dok se defolijacija …
View article: Changes in the composition and content of polyphenol compounds during the ripening of red grape varieties (Vitis vinifera L.)
Changes in the composition and content of polyphenol compounds during the ripening of red grape varieties (Vitis vinifera L.) Open
Polyphenols are secondary plant metabolites and important organic compounds present in grapes, must and wine. The importance of polyphenolic compounds present in grapes is mainly related to the quality of the wine. Those compounds affect t…
View article: One-Pot Synthesis of Sulfur-Doped TiO2/Reduced Graphene Oxide Composite (S-TiO2/rGO) with Improved Photocatalytic Activity for the Removal of Diclofenac from Water
One-Pot Synthesis of Sulfur-Doped TiO2/Reduced Graphene Oxide Composite (S-TiO2/rGO) with Improved Photocatalytic Activity for the Removal of Diclofenac from Water Open
Sulfur-doped TiO2 (S-TiO2) composites with reduced graphene oxide (rGO), wt. % of rGO equal to 0.5%, 2.75%, and 5.0%, were prepared by a one-pot solvothermal procedure. The aim was to improve photocatalytic performance in comparison to TiO…
View article: Aprotinin interacts with substrate-binding site of human dipeptidyl peptidase III
Aprotinin interacts with substrate-binding site of human dipeptidyl peptidase III Open
Human dipeptidyl peptidase III (hDPP III) is a zinc-exopeptidase of the family M49 involved in final steps of intracellular protein degradation and in cytoprotective pathway Keap1-Nrf2. Biochemical and structural properties of this enzyme …
View article: Influence of Pectolytic Enzymes and Selected Yeast Strains on The Chemical Composition of Blackberry Wines
Influence of Pectolytic Enzymes and Selected Yeast Strains on The Chemical Composition of Blackberry Wines Open
The aim of this study was to determine concentrations of individual o rganic acids, polyphenolic and aromatic compounds in blackberry wine, and to define the influence of different yeast strains (Uvaferm BDX and Lalvin 71B) and pectolytic …
View article: The first dipeptidyl peptidase III from a thermophile: Structural basis for thermal stability and reduced activity
The first dipeptidyl peptidase III from a thermophile: Structural basis for thermal stability and reduced activity Open
Dipeptidyl peptidase III (DPP III) isolated from the thermophilic bacteria Caldithrix abyssi (Ca) is a two-domain zinc exopeptidase, a member of the M49 family. Like other DPPs III, it cleaves dipeptides from the N-terminus of its substrat…
View article: Conservation of the conformational dynamics and ligand binding within M49 enzyme family
Conservation of the conformational dynamics and ligand binding within M49 enzyme family Open
The hydrogen deuterium exchange (HDX) mass spectrometry combined with molecular dynamics (MD) simulations was employed to investigate conformational dynamics and ligand binding within the M49 family (dipeptidyl peptidase III family).
View article: The Mechanism of Peptide Hydrolysis Catalysed by Dipeptidyl Peptidase III from Bacteroides thetaiotaomicron
The Mechanism of Peptide Hydrolysis Catalysed by Dipeptidyl Peptidase III from Bacteroides thetaiotaomicron Open
Dipeptidyl peptidase III (DPP III) is a zinc- dependent peptidase that cleaves dipeptides off of N-termini of its substrates. Previous studies on human DPP III reveal a reaction mechanism similar to that of thermolysin. Since the active si…
View article: Chemical composition of aronia berry wine
Chemical composition of aronia berry wine Open
View article: Kemijski sastav voćnih vina od aronije
Kemijski sastav voćnih vina od aronije Open
View article: Senzorna svojstva voćnih vina proizvedenih od kupina sorte Thornfree
Senzorna svojstva voćnih vina proizvedenih od kupina sorte Thornfree Open
View article: Human DPP III – Keap1 Interactions: A Combined Experimental And Computational Study
Human DPP III – Keap1 Interactions: A Combined Experimental And Computational Study Open
Kelch-like ECH associated protein 1 (Keap1) is a cellular sensor for oxidative stress and a negative regulator of the transcription factor Nrf2. Keap1 and Nrf2 control expression of nearly 500 genes with diverse cytoprotective functions an…
View article: Concerted nitrogen inversion and hydrogen bonding to Glu451 are responsible for protein-controlled suppression of the reverse reaction in human DPP III
Concerted nitrogen inversion and hydrogen bonding to Glu451 are responsible for protein-controlled suppression of the reverse reaction in human DPP III Open
Human dipeptidyl-peptidase III (h.DPP III) is a zinc-exopeptidase that hydrolyses dipeptides from the N-terminus of its substrates.
View article: Sensory properties of fruit wines produced from blackberry cultivar Thornfree
Sensory properties of fruit wines produced from blackberry cultivar Thornfree Open
U posljednje vrijeme u nasoj je zemlji porasla proizvodnja vocnih vina od kupina, a istraživanja o tehnologiji proizvodnje te o kemijskom sastavu i senzornim svojstvima tih vina, vrlo je malo. Cilj ovog istraživanja je bio utvrditi utjecaj…