Antonio Paolo Beltrami
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View article: Commuting by bicycle (vs. by car) is associated with improved aerobic power, microvascular function and diminished CO<sub>2</sub> output in the atmosphere
Commuting by bicycle (vs. by car) is associated with improved aerobic power, microvascular function and diminished CO<sub>2</sub> output in the atmosphere Open
The study investigated whether bicycle compared with car commuting, over relatively small distances, has positive effects on physiological variables, cardiometabolic fitness and CO 2 output in the atmosphere. Bike Commuters (11 M, 15 F; ag…
View article: The Advanced Glycation End-Products (AGE)–Receptor for AGE System (RAGE): An Inflammatory Pathway Linking Obesity and Cardiovascular Diseases
The Advanced Glycation End-Products (AGE)–Receptor for AGE System (RAGE): An Inflammatory Pathway Linking Obesity and Cardiovascular Diseases Open
The AGE (advanced glycation end-products)–RAGE (receptor for AGE) system is a pro-inflammatory pathway that contributes to the pathogenesis of obesity and obesity-related cardiovascular disorders (CVD). Circulating AGE and the soluble form…
View article: Amyloid β1‐40 Predicts Long‐Term Mortality Rate in Patients With Acute Myocardial Infarction
Amyloid β1‐40 Predicts Long‐Term Mortality Rate in Patients With Acute Myocardial Infarction Open
Background Amyloid β1‐40 (Aβ1‐40) contributes to atherosclerosis, being involved in plaque formation and destabilization. The prognostic role of Aβ1‐40 in patients with acute myocardial infarction is currently limited to non–ST‐segment–ele…
View article: Part 2—Cardiac Rehabilitation After an Acute Myocardial Infarction: Timing and Gender Differences in Adherence; Where Do We Stand?
Part 2—Cardiac Rehabilitation After an Acute Myocardial Infarction: Timing and Gender Differences in Adherence; Where Do We Stand? Open
Cardiac rehabilitation is a beneficial multidisciplinary interventional protocol that improves cardiovascular health and reduces mortality and morbidity rates in patients with cardiovascular diseases. Multiple studies have demonstrated tha…
View article: Donor Heart Preservation for Heart Transplantation: Single-Center Experience with Three Different Techniques
Donor Heart Preservation for Heart Transplantation: Single-Center Experience with Three Different Techniques Open
Objectives: In addition to traditional ice-cold storage (ICS), other techniques are emerging in the field of donor heart preservation for heart transplantation (HTx). However, in many centers, it could be difficult to justify their use, du…
View article: Part 1—Cardiac Rehabilitation After an Acute Myocardial Infarction: Four Phases of the Programme—Where Do We Stand?
Part 1—Cardiac Rehabilitation After an Acute Myocardial Infarction: Four Phases of the Programme—Where Do We Stand? Open
Cardiac rehabilitation is a well-established multidisciplinary interventional protocol that plays a pivotal role in the management and prevention of future cardiovascular events in patients with cardiovascular diseases. This patient-tailor…
View article: Protective role of the longevity-associated BPIFB4 gene on cardiac microvascular cells and cardiac aging
Protective role of the longevity-associated BPIFB4 gene on cardiac microvascular cells and cardiac aging Open
View article: Investigating the relationship between the immune response and the severity of COVID-19: a large-cohort retrospective study
Investigating the relationship between the immune response and the severity of COVID-19: a large-cohort retrospective study Open
The COVID-19 pandemic has left an indelible mark globally, presenting numerous challenges to public health. This crisis, while disruptive and impactful, has provided a unique opportunity to gather precious clinical data extensively. In thi…
View article: A Pilot Study of Exosome Proteomic Profiling Reveals Dysregulated Metabolic Pathways in Endometrial Cancer
A Pilot Study of Exosome Proteomic Profiling Reveals Dysregulated Metabolic Pathways in Endometrial Cancer Open
Background/Objectives: Endometrial cancer (EC) is the second most frequent gynecological malignant tumor in postmenopausal women. Pathogenic mechanisms related to the onset and development of the disease are still unknown. To identify dysr…
View article: Biomarkers of Importance in Monitoring Heart Condition After Acute Myocardial Infarction
Biomarkers of Importance in Monitoring Heart Condition After Acute Myocardial Infarction Open
Despite notable advancements in cardiovascular medicine, morbidity and mortality rates associated with myocardial infarction (MI) remain high. The unfavourable prognosis and absence of robust post-MI protocols necessitate further intervent…
View article: Vitamin D and Cardiovascular Health: Benefits and Controversies of Supplementation
Vitamin D and Cardiovascular Health: Benefits and Controversies of Supplementation Open
Vitamin D is a steroid hormone that exerts pleiotropic effects in the cardiovascular field, including the protection of endothelial function, the control of inflammation, the regulation of intracellular calcium homeostasis, and the modulat…
View article: Glioma-Derived Exosomes and Their Application as Drug Nanoparticles
Glioma-Derived Exosomes and Their Application as Drug Nanoparticles Open
Glioblastoma Multiforme (GBM) is the most aggressive primary tumor of the Central Nervous System (CNS) with a low survival rate. The malignancy of GBM is sustained by a bidirectional crosstalk between tumor cells and the Tumor Microenviron…
View article: 40P Patient-based models to study infiltration heterogeneity in gliomas
40P Patient-based models to study infiltration heterogeneity in gliomas Open
View article: 18P Molecular characterization of circulating tumor cells in metastatic breast cancer using shallow whole genome sequencing
18P Molecular characterization of circulating tumor cells in metastatic breast cancer using shallow whole genome sequencing Open
View article: Unraveling the relationship among insulin resistance, IGF-1, and amyloid-beta 1–40: Is the definition of type 3 diabetes applicable in the cardiovascular field?
Unraveling the relationship among insulin resistance, IGF-1, and amyloid-beta 1–40: Is the definition of type 3 diabetes applicable in the cardiovascular field? Open
View article: Investigating the relationship between the immune response and the severity of COVID-19: a large-cohort retrospective study
Investigating the relationship between the immune response and the severity of COVID-19: a large-cohort retrospective study Open
The COVID-19 pandemic has left an indelible mark globally, presenting numerous challenges to public health. This crisis, while disruptive and impactful, has provided a unique opportunity to gather precious clinical data extensively. In thi…
View article: The Deep Proteomics Approach Identified Extracellular Vesicular Proteins Correlated to Extracellular Matrix in Type One and Two Endometrial Cancer
The Deep Proteomics Approach Identified Extracellular Vesicular Proteins Correlated to Extracellular Matrix in Type One and Two Endometrial Cancer Open
Among gynecological cancers, endometrial cancer is the most common in developed countries. Extracellular vesicles (EVs) are cell-derived membrane-surrounded vesicles that contain proteins involved in immune response and apoptosis. A deep p…
View article: Extracellular vesicle features are associated with COVID‐19 severity
Extracellular vesicle features are associated with COVID‐19 severity Open
COVID‐19 is heterogeneous; therefore, it is crucial to identify early biomarkers for adverse outcomes. Extracellular vesicles (EV) are involved in the pathophysiology of COVID‐19 and have both negative and positive effects. The objective o…
View article: HCG18, LEF1AS1 and lncCEACAM21 as biomarkers of disease severity in the peripheral blood mononuclear cells of COVID-19 patients
HCG18, LEF1AS1 and lncCEACAM21 as biomarkers of disease severity in the peripheral blood mononuclear cells of COVID-19 patients Open
View article: CCDC 2253561: Experimental Crystal Structure Determination
CCDC 2253561: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2253559: Experimental Crystal Structure Determination
CCDC 2253559: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2253558: Experimental Crystal Structure Determination
CCDC 2253558: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2253560: Experimental Crystal Structure Determination
CCDC 2253560: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: BPIFB4 and its longevity-associated haplotype protect from cardiac ischemia in humans and mice
BPIFB4 and its longevity-associated haplotype protect from cardiac ischemia in humans and mice Open
Long-living individuals (LLIs) escape age-related cardiovascular complications until the very last stage of life. Previous studies have shown that a Longevity-Associated Variant (LAV) of the BPI Fold Containing Family B Member 4 ( BPIFB4 )…
View article: COVID-19-Related Myocarditis: Are We There Yet? A Case Report of COVID-19-Related Fulminant Myocarditis
COVID-19-Related Myocarditis: Are We There Yet? A Case Report of COVID-19-Related Fulminant Myocarditis Open
There is increasing evidence of cardiac involvement in COVID-19 cases, with a broad range of clinical manifestations spanning from acute life-threatening conditions such as ventricular dysrhythmias, myocarditis, acute myocardial ischemia a…
View article: HCG18, LEF1AS1 and lncCEACAM21 as biomarkers of disease severity in the Peripheral Blood Mononuclear Cells of COVID-19 patients
HCG18, LEF1AS1 and lncCEACAM21 as biomarkers of disease severity in the Peripheral Blood Mononuclear Cells of COVID-19 patients Open
Background Even after 3 years from SARS-CoV-2 identification, COVID-19 is still a persistent and dangerous global infectious disease. Significant improvements in our understanding of the disease pathophysiology have now been achieved. None…
View article: Persistent hypovitaminosis D among Italian patients with myocardial infarction
Persistent hypovitaminosis D among Italian patients with myocardial infarction Open
Funding Acknowledgements Type of funding sources: None. Background Previously we have demonstrated that hypovitaminosis D is common in the Italian population and it has a comparable deleterious effect to diabetes mellitus on survival after…
View article: The impact glycosylated hemoglobin level on admission plasma beta amyloid in patients with acute myocardial infarction
The impact glycosylated hemoglobin level on admission plasma beta amyloid in patients with acute myocardial infarction Open
Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main funding source(s): This work was supported by Regione Friuli Venezia Giulia (grant for the project “Lo scompenso cardiaco quale morbo di Alzheim…
View article: Editorial: Cardiovascular cell senescence in aging and disease
Editorial: Cardiovascular cell senescence in aging and disease Open
EDITORIAL article Front. Cardiovasc. Med., 24 March 2023Sec. Cardiovascular Biologics and Regenerative Medicine Volume 10 - 2023 | https://doi.org/10.3389/fcvm.2023.1177395
View article: Humoral and T-Cell Mediated Response after the Third Dose of mRNA Vaccines in Patients with Systemic Lupus Erythematosus on Belimumab
Humoral and T-Cell Mediated Response after the Third Dose of mRNA Vaccines in Patients with Systemic Lupus Erythematosus on Belimumab Open
Objective: To evaluate humoral and T-cell cellular-mediated immune response after three doses of SARS-CoV-2 mRNA vaccines in patients with systemic lupus erythematosus (SLE) under Belimumab. Patients and methods: 12 patients on Belimumab a…