Antoun Al Absi
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View article: Supplementary Materials and Methods from Actin Cytoskeleton Remodeling Drives Breast Cancer Cell Escape from Natural Killer–Mediated Cytotoxicity
Supplementary Materials and Methods from Actin Cytoskeleton Remodeling Drives Breast Cancer Cell Escape from Natural Killer–Mediated Cytotoxicity Open
Supplementary Materials and Methods
View article: Supplementary Movie S2. from Actin Cytoskeleton Remodeling Drives Breast Cancer Cell Escape from Natural Killer–Mediated Cytotoxicity
Supplementary Movie S2. from Actin Cytoskeleton Remodeling Drives Breast Cancer Cell Escape from Natural Killer–Mediated Cytotoxicity Open
Typical actin cytoskeleton organization observed in most NK cell-conjugated MCF-7 cells. The cell conjugate was acquired on a LSM880 laser scanning confocal microscope (Carl Zeiss) with Airyscan in the high-resolution mode, and the 3D proj…
View article: Supplementary Figures S1-S6 from Actin Cytoskeleton Remodeling Drives Breast Cancer Cell Escape from Natural Killer–Mediated Cytotoxicity
Supplementary Figures S1-S6 from Actin Cytoskeleton Remodeling Drives Breast Cancer Cell Escape from Natural Killer–Mediated Cytotoxicity Open
Supplementary Figures S1-S6 and their legends
View article: Data from Actin Cytoskeleton Remodeling Drives Breast Cancer Cell Escape from Natural Killer–Mediated Cytotoxicity
Data from Actin Cytoskeleton Remodeling Drives Breast Cancer Cell Escape from Natural Killer–Mediated Cytotoxicity Open
Elucidation of the underlying molecular mechanisms of immune evasion in cancer is critical for the development of immunotherapies aimed to restore and stimulate effective antitumor immunity. Here, we evaluate the role of the actin cytoskel…
View article: Data from Actin Cytoskeleton Remodeling Drives Breast Cancer Cell Escape from Natural Killer–Mediated Cytotoxicity
Data from Actin Cytoskeleton Remodeling Drives Breast Cancer Cell Escape from Natural Killer–Mediated Cytotoxicity Open
Elucidation of the underlying molecular mechanisms of immune evasion in cancer is critical for the development of immunotherapies aimed to restore and stimulate effective antitumor immunity. Here, we evaluate the role of the actin cytoskel…
View article: Supplementary Materials and Methods from Actin Cytoskeleton Remodeling Drives Breast Cancer Cell Escape from Natural Killer–Mediated Cytotoxicity
Supplementary Materials and Methods from Actin Cytoskeleton Remodeling Drives Breast Cancer Cell Escape from Natural Killer–Mediated Cytotoxicity Open
Supplementary Materials and Methods
View article: Supplementary Figures S1-S6 from Actin Cytoskeleton Remodeling Drives Breast Cancer Cell Escape from Natural Killer–Mediated Cytotoxicity
Supplementary Figures S1-S6 from Actin Cytoskeleton Remodeling Drives Breast Cancer Cell Escape from Natural Killer–Mediated Cytotoxicity Open
Supplementary Figures S1-S6 and their legends
View article: Supplementary Movie S3. from Actin Cytoskeleton Remodeling Drives Breast Cancer Cell Escape from Natural Killer–Mediated Cytotoxicity
Supplementary Movie S3. from Actin Cytoskeleton Remodeling Drives Breast Cancer Cell Escape from Natural Killer–Mediated Cytotoxicity Open
Time lapse imaging movie showing typical actin cytoskeleton configurations and dynamics in MDA-MB-231 cells upon NK cell attack. Individual Z stacks were taken every minute over a period of 2 hours. Time lapse movies were assembled from th…
View article: Supplementary Movie S1. from Actin Cytoskeleton Remodeling Drives Breast Cancer Cell Escape from Natural Killer–Mediated Cytotoxicity
Supplementary Movie S1. from Actin Cytoskeleton Remodeling Drives Breast Cancer Cell Escape from Natural Killer–Mediated Cytotoxicity Open
Typical actin cytoskeleton organization observed in most NK cell-conjugated MDA-MB-231 cells. The cell conjugate was acquired on a LSM880 laser scanning confocal microscope (Carl Zeiss) with Airyscan in the high-resolution mode, and the 3D…
View article: Supplementary Movie S3. from Actin Cytoskeleton Remodeling Drives Breast Cancer Cell Escape from Natural Killer–Mediated Cytotoxicity
Supplementary Movie S3. from Actin Cytoskeleton Remodeling Drives Breast Cancer Cell Escape from Natural Killer–Mediated Cytotoxicity Open
Time lapse imaging movie showing typical actin cytoskeleton configurations and dynamics in MDA-MB-231 cells upon NK cell attack. Individual Z stacks were taken every minute over a period of 2 hours. Time lapse movies were assembled from th…
View article: Supplementary Movie S4. from Actin Cytoskeleton Remodeling Drives Breast Cancer Cell Escape from Natural Killer–Mediated Cytotoxicity
Supplementary Movie S4. from Actin Cytoskeleton Remodeling Drives Breast Cancer Cell Escape from Natural Killer–Mediated Cytotoxicity Open
Time lapse imaging movie showing typical actin cytoskeleton configurations and dynamics in MCF-7 cells upon NK cell attack. Individual Z stacks were taken every minute over a period of 77 minutes. Time lapse movies were assembled from the …
View article: Supplementary Movie S1. from Actin Cytoskeleton Remodeling Drives Breast Cancer Cell Escape from Natural Killer–Mediated Cytotoxicity
Supplementary Movie S1. from Actin Cytoskeleton Remodeling Drives Breast Cancer Cell Escape from Natural Killer–Mediated Cytotoxicity Open
Typical actin cytoskeleton organization observed in most NK cell-conjugated MDA-MB-231 cells. The cell conjugate was acquired on a LSM880 laser scanning confocal microscope (Carl Zeiss) with Airyscan in the high-resolution mode, and the 3D…
View article: Supplementary Movie S2. from Actin Cytoskeleton Remodeling Drives Breast Cancer Cell Escape from Natural Killer–Mediated Cytotoxicity
Supplementary Movie S2. from Actin Cytoskeleton Remodeling Drives Breast Cancer Cell Escape from Natural Killer–Mediated Cytotoxicity Open
Typical actin cytoskeleton organization observed in most NK cell-conjugated MCF-7 cells. The cell conjugate was acquired on a LSM880 laser scanning confocal microscope (Carl Zeiss) with Airyscan in the high-resolution mode, and the 3D proj…
View article: Supplementary Movie S4. from Actin Cytoskeleton Remodeling Drives Breast Cancer Cell Escape from Natural Killer–Mediated Cytotoxicity
Supplementary Movie S4. from Actin Cytoskeleton Remodeling Drives Breast Cancer Cell Escape from Natural Killer–Mediated Cytotoxicity Open
Time lapse imaging movie showing typical actin cytoskeleton configurations and dynamics in MCF-7 cells upon NK cell attack. Individual Z stacks were taken every minute over a period of 77 minutes. Time lapse movies were assembled from the …
View article: Actin Cytoskeleton Straddling the Immunological Synapse between Cytotoxic Lymphocytes and Cancer Cells
Actin Cytoskeleton Straddling the Immunological Synapse between Cytotoxic Lymphocytes and Cancer Cells Open
The immune system is a fundamental part of the tumor microenvironment. In particular, cytotoxic lymphocytes, such as cytolytic T cells and natural killer cells, control tumor growth and disease progression by interacting and eliminating tu…
View article: Do tumor cells escape from natural killer cell cytotoxicity by mimicking dendritic cells?
Do tumor cells escape from natural killer cell cytotoxicity by mimicking dendritic cells? Open
View article: Actin Cytoskeleton Remodeling Drives Breast Cancer Cell Escape from Natural Killer–Mediated Cytotoxicity
Actin Cytoskeleton Remodeling Drives Breast Cancer Cell Escape from Natural Killer–Mediated Cytotoxicity Open
Elucidation of the underlying molecular mechanisms of immune evasion in cancer is critical for the development of immunotherapies aimed to restore and stimulate effective antitumor immunity. Here, we evaluate the role of the actin cytoskel…
View article: Role of the actin cytoskeleton in breast cancer cell resistance to natural killer cells
Role of the actin cytoskeleton in breast cancer cell resistance to natural killer cells Open
Tumor immune evasion plays a central role in cancer progression and is a major hurdle to effective immunotherapy. In this Thesis, we examine the role of the actin cytoskeleton in breast cancer cell resistance to natural killer (NK) cell-me…
View article: Hypoxia promotes breast cancer cell invasion through HIF-1α-mediated up-regulation of the invadopodial actin bundling protein CSRP2
Hypoxia promotes breast cancer cell invasion through HIF-1α-mediated up-regulation of the invadopodial actin bundling protein CSRP2 Open
View article: CRP2, a new invadopodia actin bundling factor critically promotes breast cancer cell invasion and metastasis
CRP2, a new invadopodia actin bundling factor critically promotes breast cancer cell invasion and metastasis Open
A critical process underlying cancer metastasis is the acquisition by tumor cells of an invasive phenotype. At the subcellular level, invasion is facilitated by actin-rich protrusions termed invadopodia, which direct extracellular matrix (…