Explanipedia

Otogenic meningitis in children Open

Riste Saat, Anu Laulajainen‐Hongisto, Antti A. Aarnisalo · 2025

Purpose Otogenic meningitis is a rare but potentially life-threatening intracranial complication of otitis media (OM). Our aim was to study the incidence of childhood otogenic meningitis and to compare clinical presentation, causative path…

Neurological sequelae after childhood bacterial meningitis Open

Laura Lempinen, Riste Saat, Sakke Niemelä, Anu Laulajainen‐Hongisto, Antti A. Aarnisalo , et al. · 2024

The purpose of this study is to evaluate childhood bacterial meningitis (BM): incidence, clinical presentation, causative pathogens, diagnostics, and outcome (neurological sequelae, hearing loss, and death). A retrospective review of all c…

Hearing loss and neurological sequelae after childhood bacterial meningitis Open

Laura Lempinen, Riste Saat, Sakke Niemelä, Anu Laulajainen‐Hongisto, Antti A. Aarnisalo , et al. · 2024

Purpose: To evaluate childhood bacterial meningitis (BM): incidence, clinical presentation, causative pathogens, diagnostics, and outcome (neurological sequelae, hearing loss and death). Methods: A retrospective review of all children aged…

Microbiome of the External Auditory Canal: Changes After Long-Term Hearing Aid Use Open

Atte Sjövall, Ella Mustanoja, Annina Lyyski, Petri Auvinen, Juha Silvola , et al. · 2024

Objective To investigate the microbial changes of long-term hearing aid use culture independently. Study design Cross-sectional study. Patients Fifty long-term hearing aid users and 80 volunteer controls with asymptomatic ears. Interventio…

Spread of the intracochlear electrical field: Implications for assessing electrode array location in cochlear implantation Open

Samuel Söderqvist, Ville Sivonen, Juha Koivisto, Antti A. Aarnisalo, Saku T. Sinkkonen · 2023

The electrode-generated intracochlear electrical field (EF) spreads widely along the scala tympani surrounded by poorly-conducting tissue and it can be measured with monopolar transimpedance matrix (TIM_mp). Bipolar TIM (TIM_…

Auditory Steady-State Response and Hearing Impairment in Survivors of Childhood Bacterial Meningitis in Luanda, Angola Open

Mariia Karppinen, Emilie Rugemalira, Okko Savonius, Manuel Leite Cruzeiro, Antti A. Aarnisalo , et al. · 2023

Survivors of childhood bacterial meningitis (BM) often develop hearing impairment (HI). In low- and middle-income countries (LMICs), BM continues to be a significant cause of hearing disability. We assessed hearing among BM survivors using…

Assessment of subjective image quality, contrast to noise ratio and modulation transfer function in the middle ear using a novel full body cone beam computed tomography device Open

Anssi-Kalle Heikkinen, Valtteri Rissanen, Antti A. Aarnisalo, Kristofer Nyman, Saku T. Sinkkonen , et al. · 2023

Background Multi slice computed tomography (MSCT) is the most common used method in middle ear imaging. However, MSCT lacks the ability to distinguish the ossicular chain microstructures in detail resulting in poorer diagnostic outcomes. N…

Feasibility of 3D-printed middle ear prostheses in partial ossicular chain reconstruction Open

Anssi-Kalle Heikkinen, Sini Lähde, Valtteri Rissanen, Mika Salmi, Antti A. Aarnisalo , et al. · 2023

Despite advances in prosthesis materials, operating microscopes and surgical techniques during the last 50 years, long-lasting hearing improvement remains a challenge in ossicular chain reconstruction. Failures in the reconstruction are ma…

Acute Acoustic Trauma after Exposure to Assault Rifle Noise among Conscripts in the Finnish Defence Forces—A Population-Based Survey Open

Markku Toivonen, Rauno Pääkkönen, Riina Niemensivu, Antti A. Aarnisalo, Antti Mäkitie · 2023

Conscripts are exposed to various sources of impulse noise despite hearing protection recommendations. The aim of this study was to investigate the frequency of acute acoustic trauma (AAT) among conscripts after exposure to assault rifle n…

OPTIMISING THE PARAMETERS OF COCHLEAR IMPLANT IMAGING WITH CONE-BEAM COMPUTED TOMOGRAPHY Open

Samuel Söderqvist, Ville Sivonen, Antti A. Aarnisalo, Harri Karppi, Saku T. Sinkkonen , et al. · 2023

With computed tomography (CT), the delicate structures of the inner ear may be hard to visualise, which a cochlear implant (CI) electrode array can further complicate. The usefulness of a novel cone-beam CT device in CI recipient’s inner e…

Working-age first-time hearing aid users’ self-reported outcomes Open

Minna Laakso, Jari Lipsanen, Kati Pajo, Inkeri Salmenlinna, Tarja Aaltonen , et al. · 2022

Working-age HA users reported better HA outcomes than older adults in previous studies. Coping in work life may be a strong motivator for active HA use. Considering that younger age and positive expectations resulted in better outcomes, ea…

Aerosol Generation During Otologic Surgery Open

Mari Lahelma, Lotta‐Maria Oksanen, Noora Rantanen, Saku T. Sinkkonen, Antti A. Aarnisalo , et al. · 2022

Objective To assess whether aerosol generation occurs during otologic surgery, to define which instruments are aerosol generating, and to identify factors that enhance safety in protection against airborne pathogens, such as severe acute r…

Working-age first-time hearing aid users’ self-reported outcomes Open

Minna Laakso, Jari Lipsanen, Kati Pajo, Inkeri Salmenlinna, Tarja Aaltonen , et al. · 2022

To study patient-reported hearing aid (HA) rehabilitation outcomes, social-communicative functioning, and expectations/experiences during eight months of HA use. Three self-reporting instruments, the International Outcome Inventory for Hea…

MANF supports the inner hair cell synapse and the outer hair cell stereocilia bundle in the cochlea Open

Kuu Ikäheimo, Anni Herranen, Vilma Iivanainen, Tuuli Lankinen, Antti A. Aarnisalo , et al. · 2021

Failure in the structural maintenance of the hair cell stereocilia bundle and ribbon synapse causes hearing loss. Here, we have studied how ER stress elicits hair cell pathology, using mouse models with inactivation of Manf (mesencephalic …

Spoken Language Skills in Children With Bilateral Hearing Aids or Bilateral Cochlear Implants at the Age of Three Years Open

Taina Välimaa, Sari Kunnari, Antti A. Aarnisalo, Aarno Dietz, Antti Hyvärinen , et al. · 2021

Objectives: Early hearing aid (HA) fitting and cochlear implants (CIs) aim to reduce the effects of hearing loss (HL) on spoken language development. The goals of this study were (1) to examine spoken language skills of children with bilat…

Improvements in Hearing and in Quality of Life after Sequential Bilateral Cochlear Implantation in a Consecutive Sample of Adult Patients with Severe-to-Profound Hearing Loss Open

Ville Sivonen, Saku T. Sinkkonen, Tytti Willberg, Satu Lamminmäki, Hilkka Jääskelä-Saari , et al. · 2021

Bilateral cochlear implantation is increasing worldwide. In adults, bilateral cochlear implants (BICI) are often performed sequentially with a time delay between the first (CI1) and the second (CI2) implant. The benefits of BICI have been …

Hearing Impairment in Angolan Children with Acute Bacterial Meningitis With and Without Otitis Media and Otorrhea Open

Laura Lempinen, Anu Laulajainen‐Hongisto, Antti A. Aarnisalo, Luís Bernardino, Heikki Peltola , et al. · 2021

Background: Bacterial meningitis (BM) is a common cause of hearing loss in childhood. Our aim was to investigate bacterial etiology, hearing impairment, and outcome in childhood BM with vs. without otitis media (OM) in the resource-poor se…

Intraoperative transimpedance and spread of excitation profile correlations with a lateral-wall cochlear implant electrode array Open

Samuel Söderqvist, Satu Lamminmäki, Antti A. Aarnisalo, Timo Hirvonen, Saku T. Sinkkonen , et al. · 2021

Development of otology specific outcome measure: Ear Outcome Survey-16 (EOS-16) Open

Juha Laakso, Juha Silvola, Timo Hirvonen, Samuli Suutarla, Ilkka Kivekäs , et al. · 2021

EOS-16 has been created according to the HRQoL survey guidelines with a versatile nationwide patient population. The survey has been validated and can be used for a wide range of chronic ear diseases as a HRQoL instrument.

Susacin oireyhtymä: silmänpohjan, sisäkorvan ja aivojen pienten valtimoiden tulehdussairaus Open

Sini M. Laakso, Pentti Tienari, Sanna Seitsonen, Petri Tommila, Tom Pettersson , et al. · 2021

Evaluation of pure-tone audiometric protocols in vestibular schwannoma screening Open

Matej Vnencak, Elina Huttunen, Antti A. Aarnisalo, Jussi Jero, Katja Liukkonen , et al. · 2020

The objective was to evaluate the pure-tone audiogram-based screening protocols in VS diagnostics. We retrospectively analyzed presenting symptoms, pure tone audiometry and MRI finding from 246 VS patients and 442 controls were collected t…

Microbiome of the Healthy External Auditory Canal Open

Atte Sjövall, Velma T. E. Aho, Taneli Hyyrynen, Teemu J. Kinnari, Petri Auvinen , et al. · 2020

Objective: To investigate the microbiota of the healthy external auditory canal (EAC) culture-independently and to evaluate the usefulness of the swabbing method in collecting EAC microbiota samples. Study Design: Cohort study. Patients: F…

An exploratory investigation of speech recognition thresholds in noise with auralisations of two reverberant rooms Open

Antti Kuusinen, Eero Saariniemi, Ville Sivonen, Aarno Dietz, Antti A. Aarnisalo , et al. · 2020

Auralisations may offer information on speech recognition performance that is not obtained with a test without reverberation. However, more complex stimuli and/or higher signal-to-noise ratios should be used in the future.

Tinnitus and suicide: An unresolved relation Open

Annett Szibor, Antti Mäkitie, Antti A. Aarnisalo · 2019

Tinnitus is an auditory phantom sensation which can be a devastating condition for the affected person causing annoyance and discomfort. It may be associated with psychiatric conditions. Patients with highly annoying tinnitus and different…

Bacterial biofilm in salivary stones Open

Ramón Pérez‐Tanoira, Antti A. Aarnisalo, Aaro Haapaniemi, Riitta Saarinen, Pentti Kuusela , et al. · 2019

Salivary stones are susceptible to bacterial biofilm formation, which could be related with the development and severity of the inflammation and the refractory nature of the disease. Sonication of salivary gland stones could be a useful me…

Attenuation of Positive Valence in Ratings of Affective Sounds by Tinnitus Patients Open

Annett Szibor, Jarmo Lehtimäki, Jukka Ylikoski, Antti A. Aarnisalo, Antti Mäkitie , et al. · 2018

Affective processing appears to be altered in tinnitus, and the condition is to a large extent characterized by the emotional reaction to the phantom sound. Psychophysiological models of tinnitus and supporting brain imaging studies have s…

Sisäkorvaistute - kokeellisesta hoidosta arkipäivän kuntoutukseksi Open

Aarno Dietz, Tytti Willberg, Ville Sivonen, Antti A. Aarnisalo · 2018

Sisäkorvaistutehoito sopii sekä synnynnäisen vaikea-asteisen kuulovian että etenevän kuulovian hoidoksi. Istutteella voidaan saavuttaa hyvä puheentunnistuskyky vaikea-asteisessa kuulonalenemassa. Hoito on osoitettu kustannusvaikuttavaksi k…

Prognostic Value and Changes of Auditory Brain Stem Response in Children With Bacterial Meningitis in Luanda, Angola Open

Mariia Karppinen, Atte Sjövall, Tuula Pelkonen, Luís Bernardino, Irmeli Roine , et al. · 2018

Objective: To assess the role of single and repeated auditory brain stem response (ABR) in predicting mortality and severe neurological injury among children having bacterial meningitis (BM) in Luanda, Angola. Methods: The morphology of AB…

Patient satisfaction in the long-term effects of Eustachian tube balloon dilation is encouraging Open

Veera Luukkainen, Matej Vnencak, Antti A. Aarnisalo, Jussi Jero, Saku T. Sinkkonen · 2017

Patient satisfaction in the long-term effects of BET is encouraging. These results may help clinicians in preoperative patient selection and counselling.

Hearing disorder from music; a neglected dysfunction Open

Annett Szibor, Petteri Hyvärinen, Jarmo Lehtimäki, Ulla Pirvola, Matti Ylikoski , et al. · 2017

Hearing abilities were normal in about two-thirds of the tinnitus patients. Tinnitus was experienced most often as a high-frequency tone (83%). The Tinnitus Handicap Inventory (THI) scores ranged from 0 to 94 with an average score of 43.1.…

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