Explanipedia

Androgen deprivation therapy and overall survival after hip fracture surgery in patients with prostate cancer Open

Silja Vuorlaakso, Minna Laitinen, Heini Huhtala, Antti Kaipia, Jussi Kosola · 2025

Background and aims: Androgen deprivation therapy (ADT), either by surgical or chemical castration, is the standard treatment for metastatic prostate cancer (PCa). ADT induces osteoporosis and increases the risk of osteoporotic fractures, …

Psychometric properties and content of instruments for assessing penile cancer patients’ quality of life: A systematic review Open

Anu Soikkeli‐Jalonen, Suvi Vierelä, Antti Kaipia, Eeva Harju, Elina Haavisto · 2025

Transdermal oestradiol and exercise in androgen deprivation therapy ( <span>ESTRACISE</span> ): protocol Open

Ilkka Jussila, Juha P. Ahtiainen, Eija K. Laakkonen, Aino Siltari, Antti Kaipia , et al. · 2024

Objective To report the protocol of a study evaluating the efficacy of transdermal oestradiol (E2) gel in reducing the adverse effects of androgen deprivation therapy (ADT), specifically on sexual function, and to assess the utility of E2 …

Prostate Cancer Screening With PSA, Kallikrein Panel, and MRI Open

Anssi Auvinen, Teuvo L.J. Tammela, Tuomas Mirtti, Hans Lilja, Teemu Tolonen , et al. · 2024

Importance Prostate-specific antigen (PSA) screening has potential to reduce prostate cancer mortality but frequently detects prostate cancer that is not clinically important. Objective To describe rates of low-grade (grade group 1) and hi…

Comparison of Bacillus Calmette-Guérin Maintenance Therapy with Monthly Instillations and the Southwest Oncology Group Protocol in the Treatment of Non–muscle-invasive Bladder Cancer Open

Pertti Nurminen, Antti Nummi, Olli Kesti, Otto Ettala, Mikael Högerman , et al. · 2023

In this study, we compared two schedules of intravesical bacillus Calmette-Guérin (BCG) treatment used in the treatment of non-muscle-invasive bladder cancer. We found that there were no significant differences between the two instillation…

Visual Analogue Scale and Expanded Prostate Cancer Index Composite-26 in the Evaluation of Urinary Continence Recovery After Three-Dimensional Laparoscopic Radical Prostatectomy, a Single-Center Prospective Registered Study Open

Jaakko Valli, Henry Haapiainen, Teemu J. Murtola, Heini Huhtala, Antti Kaipia , et al. · 2023

ObjectiveTo assess the correlation between the Visual Analogue Scale (VAS) and the Expanded Prostate Cancer Index Composite (EPIC)-26 in the evaluation of urinary continence (UC) recovery after 3-dimensional laparoscopic radical prostatect…

Visual Analogue Scale (VAS) in the Evaluation of Functional Outcomes After Three-dimensional Laparoscopic Prostatectomy Open

Henry Haapiainen, Jaakko Valli, Teemu J. Murtola, Heini Huhtala, Antti Kaipia , et al. · 2022

Our study shows a strong correlation between VAS and EPIC-26 urinary incontinence and sexual domains. In daily clinical practice VAS-scale may serve as a simple tool to evaluate the key functional outcomes of radical prostatectomy.

Periodic trends in geographical variation of prostate cancer incidence and mortality in Finland between 1985 and 2019 Open

Heikki Seikkula, Antti Kaipia, Peter J. Boström, Nea Malila, Janne Pitkäniemi , et al. · 2022

Regional variation in the incidence rate of PCa became more evident after initiation of PSA testing in Finland, which indicates that early diagnostic practice (PSA testing) of PCa has been different in different parts of the country. Varia…

Creating an inexpensive hospital-wide surgical complication register for performance monitoring: a cohort study Open

I. Saarinen, Antti Malmivaara, Heini Huhtala, Antti Kaipia · 2022

Objectives Basic tools that measure a hospital’s performance are required in order to benchmark or compare hospitals, but multispecialty institutional registries are rarely reported, and there is no consensus on their standard definitions …

3D laparoscopic prostatectomy: results of multicentre study Open

Henry Haapiainen, Antti Kaipia, Teemu J. Murtola, Heikki Seikkula, Marjo Seppänen , et al. · 2022

3D LRP shows promising results, comparable to similar studies published on RALP.

Periodic trends in geographical variation of prostate cancer incidence and mortality in Finland between 1985 and 2019 Open

Heikki Seikkula, Antti Kaipia, Peter J. Boström, Nea Malila, Janne Pitkäniemi , et al. · 2022

Evaluation of regional variation of prostate cancer (PCa) incidence and PCa-specific mortality is essential in the assessment of equity in a national healthcare system. We evaluated PCa incidence and PCa-specific mortality between differen…

Health-Related Quality of Life, Self-esteem and Sexual Functioning Among Patients Operated for Penile Cancer – A Cross-sectional Study Open

Eeva Harju, Tomi Pakarainen, Hanna Vasarainen, Minna Törnävä, Mika Helminen , et al. · 2021

Background Penile cancer surgery affects physical, psychological, and sexual well-being, but the patient- and treatment-related factors predisposing to worse health-related quality of life (HRQoL) have not been well characterized. Aim We r…

Hyperuricemia Is Not an Independent Predictor of Erectile Dysfunction Open

Antti Tuokko, Teemu J. Murtola, Päivi Korhonen, Antti Kaipia · 2021

Introduction Erectile dysfunction (ED) is strongly associated with physiological and metabolic disturbances, and hyperuricemia has been proposed to predict the onset of ED. Aim To investigate if hyperuricemia is an independent predictor fo…

Reply to Commentary on “Repetitive Transcranial Magnetic Stimulation for Chronic Prostatitis/Chronic Pelvic Pain Syndrome: A Prospective Pilot Study” Open

Jussi Nikkola, Anu Holm, Marjo Seppänen, Teemu Joutsi, Esa Rauhala , et al. · 2020

See the letter "Commentary on "Repetitive Transcranial Magnetic Stimulation for Chronic Prostatitis/Chronic Pelvic Pain Syndrome: A Prospective Pilot Study"" on page 296.

Repetitive Transcranial Magnetic Stimulation for Chronic Prostatitis/Chronic Pelvic Pain Syndrome: A Prospective Pilot Study Open

Nikkola Jussi, Anu Holm, Marjo Seppänen, Joutsi Teemu, Rauhala Esa , et al. · 2020

Purpose: To evaluate the feasibility, efficacy, and safety of repetitive transcranial magnetic stimulation (rTMS) in patients with treatment-resistant chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS).Methods: Eleven patients with…

Survival and mortality of elderly men with localized prostate cancer managed with primary androgen deprivation therapy or by primary observation Open

Heikki Seikkula, Peter J. Boström, Karri Seppä, Janne Pitkäniemi, Nea Malila , et al. · 2020

Survival and mortality of elderly men with localized prostate cancer managed with primary androgen deprivation therapy or by primary observation Open

Heikki Seikkula, Peter J. Boström, Karri Seppä, Janne Pitkäniemi, Nea Malila , et al. · 2020

Background: Androgen deprivation therapy (ADT) remains a primary treatment for localized prostate cancer (PCa) even though there is no evidence that its use is beneficial in the absence of curative treatment. Methods: Men aged ≥70 years ( …

Survival and mortality of elderly men with localized prostate cancer managed with primary androgen deprivation therapy or by primary observation Open

Heikki Seikkula, Peter J. Boström, Karri Seppä, Janne Pitkäniemi, Nea Malila , et al. · 2019

Background: Androgen deprivation therapy (ADT) remains a primary treatment for localized prostate cancer (PCa) even though there is no evidence that its use is beneficial in the absence of curative treatment. Methods: Men aged ≥70 years ( …

A comparison of survival and mortality outcomes for older men with localized prostate cancer treated with either primary androgen deprivation therapy or primary observation Open

Heikki Seikkula, Peter J. Boström, Karri Seppä, Janne Pitkäniemi, Nea Malila , et al. · 2019

Background Androgen deprivation therapy (ADT) remains the primary treatment for localized prostate cancer (PCa) even though there is no evidence that its use is beneficial in the absence of curative treatment.Material and methods Finnish C…

Systematic review of hospital-wide complication registries Open

I. Saarinen, Antti Malmivaara, Ritva Miikki, Antti Kaipia · 2019

Background An institutional registry covering all surgical specialties could be an implementation tool in quality benchmarking between hospitals and aid determination of their cost-effectiveness. The objective of this systematic literatur…

Spanish translation section Open

Eisuke Booka, Hiroya Takeuchi, Kazuto Suda, Kazumasa Fukuda, Robert M. Nakamura , et al. · 2018

Systematic review of hospital-wide complication registries Open

I. Saarinen, Antti Malmivaara, Ritva Miikki, Antti Kaipia · 2018

Ideal surgical quality monitoring systems should be real-time, contain patient-related risk factors, and encompass all surgical specialties. At present, such institutional registries are rarely reported and no consensus exists on their sta…

Urine cytology is a feasible tool for assessing erythematous bladder lesions after bacille Calmette‐Guérin (BCG) treatment Open

Pertti Nurminen, Otto Ettala, Marjo Seppänen, Pekka Taimen, Peter J. Boström , et al. · 2018

Objectives To investigate the need to biopsy erythematous lesions of the bladder after bacille Calmette‐Guérin (BCG) treatment as well as the diagnostic value of voided urine cytology in the detection of recurrence. Materials and Methods D…

Allopurinol and risk of benign prostatic hyperplasia in a Finnish population-based cohort Open

Ville Kukko, Antti Kaipia, Kirsi Talala, Kimmo Taari, Teuvo L.J. Tammela , et al. · 2018

The impact of socioeconomic status on stage specific prostate cancer survival and mortality before and after introduction of PSA test in Finland Open

Heikki Seikkula, Antti Kaipia, Heidi Ryynänen, Karri Seppä, Janne Pitkäniemi , et al. · 2017

Socioeconomic status (SES) has an impact on prostate cancer (PCa) outcomes. Men with high SES have higher incidence and lower mortality of PCa versus lower SES males. PCa cases diagnosed in Finland in 1985–2014 ( N = 95,076) were identifie…

Complications after surgical treatment of femoral neck fractures in men with alcohol dependence syndrome: retrospective register analysis of 154 cases Open

Jussi Kosola, Antti Kaipia, Minna Laitinen, Jyrki Nieminen · 2017

Contemporary and past challenges of prostate cancer diagnostics Open

Antti Kaipia, Jarno Riikonen · 2017

The complex interplay of sex steroids manifested by endocrine treatment of prostate cancer Open

Antti Kaipia, Harri Visapää · 2017

Stage-specific mortality and survival trends of prostate cancer patients in Finland before and after introduction of PSA Open

Heikki Seikkula, Antti Kaipia, Matti Rantanen, Janne Pitkäniemi, Nea Malila , et al. · 2017

From 1985 to 2009, the SMR among men diagnosed with PCa decreased significantly in Finland. Among men with localized PCa, the SMR decreased even below that of the Finnish male population. This and the increased difference between relative …

Initiation of robot-assisted radical prostatectomies in Finland: Impact on centralization and quality of care Open

Jarno Riikonen, Antti Kaipia, Anssi Pétas, Antero Horte, Juha Koskimäki , et al. · 2016

Objective The aim of this study was to analyze the impact of introduction of robot-assisted prostate surgery and its quality measures in Finland from 2008 to 2012. Materials and methods Registry data were collected for time trends and nati…

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