Antti Luikku
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View article: Mortality Outcomes After Spinal Cord Stimulation: A 10-Year Survival Analysis of 330 Patients With Chronic Neuropathic Pain
Mortality Outcomes After Spinal Cord Stimulation: A 10-Year Survival Analysis of 330 Patients With Chronic Neuropathic Pain Open
BACKGROUND AND OBJECTIVES: Spinal cord stimulation (SCS) is an established but intricate therapy for neuropathic pain. Chronic pain is associated with increased mortality; however, the impact of successful SCS treatment on mortality remain…
View article: A cerebrospinal fluid synaptic protein biomarker for prediction of cognitive resilience versus decline in Alzheimer’s disease
A cerebrospinal fluid synaptic protein biomarker for prediction of cognitive resilience versus decline in Alzheimer’s disease Open
View article: Association between postoperative thromboembolic and hemorrhagic complications and clinical outcomes after surgery for chronic subdural hematoma in patients with anticoagulation therapy for atrial fibrillation
Association between postoperative thromboembolic and hemorrhagic complications and clinical outcomes after surgery for chronic subdural hematoma in patients with anticoagulation therapy for atrial fibrillation Open
View article: Deep learning assisted quantitative analysis of Aβ and microglia in patients with idiopathic normal pressure hydrocephalus in relation to cognitive outcome
Deep learning assisted quantitative analysis of Aβ and microglia in patients with idiopathic normal pressure hydrocephalus in relation to cognitive outcome Open
Neuropathologic changes of Alzheimer disease (AD) including Aβ accumulation and neuroinflammation are frequently observed in the cerebral cortex of patients with idiopathic normal pressure hydrocephalus (iNPH). We created an automated anal…
View article: Synapse protein signatures in cerebrospinal fluid and plasma predict cognitive maintenance versus decline in Alzheimer’s disease
Synapse protein signatures in cerebrospinal fluid and plasma predict cognitive maintenance versus decline in Alzheimer’s disease Open
Rates of cognitive decline in Alzheimer’s disease (AD) are extremely heterogeneous, with ages of symptom onset ranging from age 40-100 years and conversion from mild cognitive impairment to AD dementia taking 2-20 years. Development of bio…
View article: Patients’ and Caregivers’ Expectations and Acceptance of Digital Remote Monitoring at Home: The Case of Idiopathic Normal Pressure Hydrocephalus
Patients’ and Caregivers’ Expectations and Acceptance of Digital Remote Monitoring at Home: The Case of Idiopathic Normal Pressure Hydrocephalus Open
View article: Cerebrospinal Fluid Tap Test Did Not Predict Shunt Response in The Kuopio Idiopathic Normal Pressure Hydrocephalus Protocol
Cerebrospinal Fluid Tap Test Did Not Predict Shunt Response in The Kuopio Idiopathic Normal Pressure Hydrocephalus Protocol Open
View article: Novel cerebrospinal fluid biomarkers correlating with shunt responsiveness in patients with idiopathic normal pressure hydrocephalus
Novel cerebrospinal fluid biomarkers correlating with shunt responsiveness in patients with idiopathic normal pressure hydrocephalus Open
Background Idiopathic Normal pressure hydrocephalus (iNPH) is a form of adult hydrocephalus that is clinically characterized by progressive gait impairment, cognitive dysfunction, and urinary incontinence. The current standard method of tr…
View article: Patients’ and Caregivers’ Expectations and Acceptance of Digital Remote Monitoring at Home: The Case of Idiopathic Normal Pressure Hydrocephalus
Patients’ and Caregivers’ Expectations and Acceptance of Digital Remote Monitoring at Home: The Case of Idiopathic Normal Pressure Hydrocephalus Open
View article: 5-Year health-related quality of life outcome in patients with idiopathic normal pressure hydrocephalus
5-Year health-related quality of life outcome in patients with idiopathic normal pressure hydrocephalus Open
Background Health-related quality of life (HRQoL) is severely impaired in persons with idiopathic normal pressure hydrocephalus (iNPH). The HRQoL improves in a number of patients after the placement of a cerebrospinal fluid (CSF) shunt, bu…
View article: Idiopathic normal pressure hydrocephalus as a novel window for Alzheimer’s disease
Idiopathic normal pressure hydrocephalus as a novel window for Alzheimer’s disease Open
Background Idiopathic normal pressure hydrocephalus (iNPH) is characterized by gait apraxia, cognitive deterioration and urinary incontinence. Differential diagnosis with other neurodegenerative disorders like Alzheimer’s disease (AD) can …
View article: The Kuopio idiopathic normal pressure hydrocephalus protocol: initial outcome of 175 patients
The Kuopio idiopathic normal pressure hydrocephalus protocol: initial outcome of 175 patients Open
View article: Why Does the Health-Related Quality of Life in Idiopathic Normal-Pressure Hydrocephalus Fail to Improve Despite the Favorable Clinical Outcome?
Why Does the Health-Related Quality of Life in Idiopathic Normal-Pressure Hydrocephalus Fail to Improve Despite the Favorable Clinical Outcome? Open