Anu Jose
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View article: Effect of cardiomyocyte-specific lipid phosphate phosphatase 3 overexpression on high-fat diet-induced cardiometabolic dysfunction in mice
Effect of cardiomyocyte-specific lipid phosphate phosphatase 3 overexpression on high-fat diet-induced cardiometabolic dysfunction in mice Open
Lipid phosphate phosphatase 3 (LPP3) hydrolyzes bioactive lipids including lysophosphatidic acid (LPA), elevated levels of which are implicated in obesity-induced metabolic and cardiac dysfunction. We show that cardiac-specific overexpress…
View article: Lysophosphatidic acid metabolism and signaling in heart disease
Lysophosphatidic acid metabolism and signaling in heart disease Open
Lysophosphatidic acid (LPA) is a bioactive lipid that is mainly produced by the secreted lysophospholipase D, autotaxin (ATX), and signals through at least six G protein-coupled receptors (LPA1–6). Extracellular LPA is degraded through lip…
View article: Assessment of impact of structured education regarding COVID – 19 among higher secondary school children among selected schools of Kalaburagi City
Assessment of impact of structured education regarding COVID – 19 among higher secondary school children among selected schools of Kalaburagi City Open
Background: The Coronavirus disease-2019 (COVID-19) is considered as an emerging respiratory disease that is highly infectious, and was detected in December 2019 in Wuhan, China. According to WHO, Coronaviruses (CoV) are a large family of …
View article: Autotaxin-LPA-LPP3 Axis in Energy Metabolism and Metabolic Disease
Autotaxin-LPA-LPP3 Axis in Energy Metabolism and Metabolic Disease Open
Besides serving as a structural membrane component and intermediate of the glycerolipid metabolism, lysophosphatidic acid (LPA) has a prominent role as a signaling molecule through its binding to LPA receptors at the cell surface. Extracel…