Anuj Srivastava
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View article: A shape-based functional index for objective assessment of pediatric motor function
A shape-based functional index for objective assessment of pediatric motor function Open
Clinical assessments for neuromuscular disorders, such as Spinal Muscular Atrophy (SMA) and Duchenne Muscular Dystrophy (DMD), continue to rely on subjective measures to monitor treatment response and disease progression. We introduce a no…
View article: S‐<scp>GMAS</scp>: Genome‐Wide Mediation Analysis With Brain Subcortical Shape Mediators
S‐<span>GMAS</span>: Genome‐Wide Mediation Analysis With Brain Subcortical Shape Mediators Open
Mediation analysis is widely utilized in neuroscience to investigate the role of brain image phenotypes in the neurological pathways from genetic exposures to clinical outcomes. However, it is still difficult to conduct mediation analyses …
View article: Graph Network Modeling Techniques for Visualizing Human Mobility Patterns
Graph Network Modeling Techniques for Visualizing Human Mobility Patterns Open
Human mobility analysis at urban-scale requires models to represent the complex nature of human movements, which in turn are affected by accessibility to nearby points of interest, underlying socioeconomic factors of a place, and local tra…
View article: Multi-Variable Batch Bayesian Optimization in Materials Research: Synthetic Data Analysis of Noise Sensitivity and Problem Landscape Effects
Multi-Variable Batch Bayesian Optimization in Materials Research: Synthetic Data Analysis of Noise Sensitivity and Problem Landscape Effects Open
Bayesian Optimization (BO) machine learning method is increasingly used to guide experimental optimization tasks in materials science. To emulate the large number of input variables and noise-containing results in experimental materials re…
View article: Alignment of Continuous Brain Connectivity
Alignment of Continuous Brain Connectivity Open
Brain networks are typically represented by adjacency matrices, where each node corresponds to a brain region. In traditional brain network analysis, nodes are assumed to be matched across individuals, but the methods used for node matchin…
View article: Dynamic Neural Surfaces for Elastic 4D Shape Representation and Analysis
Dynamic Neural Surfaces for Elastic 4D Shape Representation and Analysis Open
We propose a novel framework for the statistical analysis of genus-zero 4D surfaces, i.e., 3D surfaces that deform and evolve over time. This problem is particularly challenging due to the arbitrary parameterizations of these surfaces and …
View article: QWhale and SARSAWhale: Energy-Efficient and Energy-Aware Algorithms for High-Load Cloud Environments
QWhale and SARSAWhale: Energy-Efficient and Energy-Aware Algorithms for High-Load Cloud Environments Open
Cloud computing has transformed resource management by providing on-demand access to shared computational resources, yet task scheduling in dynamic environments remains a critical challenge due to fluctuating workloads, varying resource av…
View article: QWhale and SARSAWhale: Energy-Efficient and Energy-Aware Algorithms for High-Load Cloud Environments
QWhale and SARSAWhale: Energy-Efficient and Energy-Aware Algorithms for High-Load Cloud Environments Open
Cloud computing has transformed resource management by providing on-demand access to shared computational resources, yet task scheduling in dynamic environments remains a critical challenge due to fluctuating workloads, varying resource av…
View article: A Shape-Based Functional Index for Objective Assessment of Pediatric Motor Function
A Shape-Based Functional Index for Objective Assessment of Pediatric Motor Function Open
Clinical assessments for neuromuscular disorders, such as Spinal Muscular Atrophy (SMA) and Duchenne Muscular Dystrophy (DMD), continue to rely on subjective measures to monitor treatment response and disease progression. We introduce a no…
View article: Statistical Emulations of Human Operational Motions in Industrial Environments
Statistical Emulations of Human Operational Motions in Industrial Environments Open
This paper addresses the critical and challenging task of developing emulators for simulating human operational motions in industrial workplaces. We conceptualize human motion as a sequence of human body shapes and develop statistical gene…
View article: Scalar-on-Shape Regression Models for Functional Data Analysis
Scalar-on-Shape Regression Models for Functional Data Analysis Open
Functional data contains two components: shape (or amplitude) and phase. This paper focuses on a branch of functional data analysis (FDA), namely Shape-Based FDA, that isolates and focuses on shapes of functions. Specifically, this paper f…
View article: Fused Gromov-Wasserstein Variance Decomposition with Linear Optimal Transport
Fused Gromov-Wasserstein Variance Decomposition with Linear Optimal Transport Open
Wasserstein distances form a family of metrics on spaces of probability measures that have recently seen many applications. However, statistical analysis in these spaces is complex due to the nonlinearity of Wasserstein spaces. One potenti…
View article: Reducing Shape-Graph Complexity with Application to Classification of Retinal Blood Vessels and Neurons
Reducing Shape-Graph Complexity with Application to Classification of Retinal Blood Vessels and Neurons Open
Shape graphs are complex geometrical structures commonly found in biological and anatomical systems. A shape graph is a collection of nodes, some connected by curvilinear edges with arbitrary shapes. Their high complexity stems from the la…
View article: A Riemannian Approach for Spatiotemporal Analysis and Generation of 4D Tree-shaped Structures
A Riemannian Approach for Spatiotemporal Analysis and Generation of 4D Tree-shaped Structures Open
We propose the first comprehensive approach for modeling and analyzing the spatiotemporal shape variability in tree-like 4D objects, i.e., 3D objects whose shapes bend, stretch, and change in their branching structure over time as they def…
View article: PERFORMANCE EVALUATION OF ELECTRIC BUSES & ADAPTATION IN INDIAN MARKET
PERFORMANCE EVALUATION OF ELECTRIC BUSES & ADAPTATION IN INDIAN MARKET Open
This research paper evaluates the performance and adaptation of electric buses in India, highlighting their potential as sustainable alternatives to diesel vehicles.It analyzes metrics such as HVAC efficiency, steering and wheel alignment,…
View article: Time-Series Analysis of Cellular Shapes Using Transported Velocity Fields
Time-Series Analysis of Cellular Shapes Using Transported Velocity Fields Open
View article: Longitudinal Elastic Shape Analysis of Brain Subcortical Structures
Longitudinal Elastic Shape Analysis of Brain Subcortical Structures Open
Background Over the past 30 years, MRI has become a ubiquitous tool for accurately visualizing the development of the brain’s subcortical structures. However, the quantification of subcortical structures is still in its infancy due to chal…
View article: Rescuing referral failures during automated diagnosis of domain-shifted medical images
Rescuing referral failures during automated diagnosis of domain-shifted medical images Open
The success of deep learning models deployed in the real world depends critically on their ability to generalize well across diverse data domains. Here, we address a fundamental challenge with selective classification during automated diag…
View article: A Wasserstein-type Distance for Gaussian Mixtures on Vector Bundles with Applications to Shape Analysis
A Wasserstein-type Distance for Gaussian Mixtures on Vector Bundles with Applications to Shape Analysis Open
This paper uses sample data to study the problem of comparing populations on finite-dimensional parallelizable Riemannian manifolds and more general trivial vector bundles. Utilizing triviality, our framework represents populations as mixt…
View article: Shape-based functional data analysis
Shape-based functional data analysis Open
Functional data analysis (FDA) is a fast-growing area of research and development in statistics. While most FDA literature imposes the classical $$\mathbb {L}^2$$ Hilbert structure on function spaces, there is an emergent need for a diffe…
View article: Shape-Graph Matching Network (SGM-net): Registration for Statistical Shape Analysis
Shape-Graph Matching Network (SGM-net): Registration for Statistical Shape Analysis Open
This paper focuses on the statistical analysis of shapes of data objects called shape graphs, a set of nodes connected by articulated curves with arbitrary shapes. A critical need here is a constrained registration of points (nodes to node…
View article: Learning Pose Image Manifolds Using Geometry-Preserving GANs and Elasticae
Learning Pose Image Manifolds Using Geometry-Preserving GANs and Elasticae Open
This paper investigates the challenge of learning image manifolds, specifically pose manifolds, of 3D objects using limited training data. It proposes a DNN approach to manifold learning and for predicting images of objects for novel, cont…
View article: Peak-Persistence Diagrams for Estimating Shapes and Functions from Noisy Data
Peak-Persistence Diagrams for Estimating Shapes and Functions from Noisy Data Open
Estimating signals underlying noisy data is a significant problem in statistics and engineering. Numerous estimators are available in the literature, depending on the observation model and estimation criterion. This paper introduces a fram…
View article: Data from Cancer Stem Cells, not Bulk Tumor Cells, Determine Mechanisms of Resistance to SMO Inhibitors
Data from Cancer Stem Cells, not Bulk Tumor Cells, Determine Mechanisms of Resistance to SMO Inhibitors Open
The emergence of treatment resistance significantly reduces the clinical utility of many effective targeted therapies. Although both genetic and epigenetic mechanisms of drug resistance have been reported, whether these mechanisms are stoc…
View article: Supplementary Table 7 from Cancer Stem Cells, not Bulk Tumor Cells, Determine Mechanisms of Resistance to SMO Inhibitors
Supplementary Table 7 from Cancer Stem Cells, not Bulk Tumor Cells, Determine Mechanisms of Resistance to SMO Inhibitors Open
Supplementary Table 7: DEG in LDE vs. control treated SI-CSC Ptch;p53 tumors
View article: Supplementary Table 5 from Cancer Stem Cells, not Bulk Tumor Cells, Determine Mechanisms of Resistance to SMO Inhibitors
Supplementary Table 5 from Cancer Stem Cells, not Bulk Tumor Cells, Determine Mechanisms of Resistance to SMO Inhibitors Open
Supplementary Table 5: mutational profiles for Fsmo;GFAP-cre SD-CSC tumors
View article: Supplementary Table 9 from Cancer Stem Cells, not Bulk Tumor Cells, Determine Mechanisms of Resistance to SMO Inhibitors
Supplementary Table 9 from Cancer Stem Cells, not Bulk Tumor Cells, Determine Mechanisms of Resistance to SMO Inhibitors Open
Supplementary Table 9: Differentially expressed proteins in LDE vs. control treated Ptch;p53 SI-CSC and SD-CSC tumors
View article: Supplementary Table 9 from Cancer Stem Cells, not Bulk Tumor Cells, Determine Mechanisms of Resistance to SMO Inhibitors
Supplementary Table 9 from Cancer Stem Cells, not Bulk Tumor Cells, Determine Mechanisms of Resistance to SMO Inhibitors Open
Supplementary Table 9: Differentially expressed proteins in LDE vs. control treated Ptch;p53 SI-CSC and SD-CSC tumors
View article: Supplementary Table 7 from Cancer Stem Cells, not Bulk Tumor Cells, Determine Mechanisms of Resistance to SMO Inhibitors
Supplementary Table 7 from Cancer Stem Cells, not Bulk Tumor Cells, Determine Mechanisms of Resistance to SMO Inhibitors Open
Supplementary Table 7: DEG in LDE vs. control treated SI-CSC Ptch;p53 tumors
View article: Supplementary Figures and Tables 1-2 from Cancer Stem Cells, not Bulk Tumor Cells, Determine Mechanisms of Resistance to SMO Inhibitors
Supplementary Figures and Tables 1-2 from Cancer Stem Cells, not Bulk Tumor Cells, Determine Mechanisms of Resistance to SMO Inhibitors Open
Supplementary figures and Tables 1 & 2