Anup Acharya
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View article: ESBL-Producing Escherichia coli and Klebsiella pneumoniae Exhibit Divergent Paths During In-Human Evolution Towards Carbapenem Resistance
ESBL-Producing Escherichia coli and Klebsiella pneumoniae Exhibit Divergent Paths During In-Human Evolution Towards Carbapenem Resistance Open
Treatment of infections caused by ESBL-producing Escherichia coli (EC) and Klebsiella pneumoniae (KP) with carbapenem antibiotics can lead to the development of carbapenem resistance over time through the acquisition of porin mutations and…
View article: Patency of Aditus Ad Antrum in Chronic Otitis Media Mucosal Type Undergoing Tympanoplasty
Patency of Aditus Ad Antrum in Chronic Otitis Media Mucosal Type Undergoing Tympanoplasty Open
INTRODUCTIONChronic otitis media (COM) mucosal type is a prevalent condition characterized by chronic inflammation of the middle ear, often leading to persistent ear discharge and tympanic membrane perforation. This study aimed to evaluate …
View article: The<i>Legionella pneumophila</i>peptidoglycan recycling kinase, AmgK, is essential for survival and replication inside host alveolar macrophages
The<i>Legionella pneumophila</i>peptidoglycan recycling kinase, AmgK, is essential for survival and replication inside host alveolar macrophages Open
Bacterial cells are surrounded by a dynamic cell wall which in part is made up of a mesh-like peptidoglycan (PG) layer that provides the cell with structural integrity and resilience. In Gram-positive bacteria, this layer is thick and robu…
View article: Traumatic Perforation – Etiology, Outcome and Factors Affecting the Outcome
Traumatic Perforation – Etiology, Outcome and Factors Affecting the Outcome Open
INTRODUCTION
Traumatic tympanic membrane perforation is the most common type of trauma – induced otologic dysfunction. The study is aimed to evaluate factors affecting healing of truamatic tympanic membrane perforation after 12 weeks.
MA…
View article: Myringoplasty graft uptake: Short and long term outcome
Myringoplasty graft uptake: Short and long term outcome Open
INTRODUCTIONMyringoplasty is surgical procedure to restore tympanic membrane perforation. The objective of the study is to compare overall success rate of myringoplasty after 6 weeks and 6 months post-operatively. MATERIAL AND METHODSThis …
View article: Mobile Guide for Museum in Context of International Mountain Museum, Nepal
Mobile Guide for Museum in Context of International Mountain Museum, Nepal Open
This paper aims to utilization of information technology at museum to provide the information about the museum and its artifacts properly in easier way with the help of digital devices such as mobile to the visitors.
View article: Research Trends on the Application of Information Technologies and Digital Innovations during Covid-19 Pandemic
Research Trends on the Application of Information Technologies and Digital Innovations during Covid-19 Pandemic Open
This paper covers the background information and research overview of application of information technologies and digital innovations during COVID-19 pandemic and puts forward the prospects of digital healthcare, business, academic and ind…
View article: Smart Farming Based on IoT: Nepal Perspective
Smart Farming Based on IoT: Nepal Perspective Open
This paper is about how Internet of Things (IoT) plays a vital role in farming.IoT based farming is the smart farming system so that if we apply this technology with traditional farming then it would definitely be emerging because of its a…
View article: Anterior Ethmoidal Nerve Block In Prevention of Post-Operative Agitation Following Nasal Surgeries with Nasal Packs Under General Anesthesia: An Experimental Study
Anterior Ethmoidal Nerve Block In Prevention of Post-Operative Agitation Following Nasal Surgeries with Nasal Packs Under General Anesthesia: An Experimental Study Open
INTRODUCTION
Postoperative agitation or emergence agitation during recovery from anesthesia is an important complication of General Anesthesia (GA) especially in otolaryngological surgeries, and nasal surgery in particular. It is potentia…
View article: Efficacy and cost-effectiveness analysis of steroid in treatment of Otitis Media with Effusion (OME) in children: A Randomized Trial
Efficacy and cost-effectiveness analysis of steroid in treatment of Otitis Media with Effusion (OME) in children: A Randomized Trial Open
Background: Otitis media with effusion (OME) is a common disorder in children and lacks international consensus for its treatment. Out of various treatment options, few studies have show promising benefits of steroids for this condition. T…
View article: Is Diclofenac Gargle Effective in Alleviating Post-Tonsillectomy Pain in Adults?
Is Diclofenac Gargle Effective in Alleviating Post-Tonsillectomy Pain in Adults? Open
Introduction: Pain in the post-operative period is a major concern following tonsillectomy in an adult resulting in prolonged hospital stay, decreased oral intake and absence from work. Various techniques and medications have been tried to…
View article: Role and Adverse Effects of Premedication for Reducing Pain and Discomfort during Fiberoptic Nasal Pharyngoscopy and Laryngoscopy
Role and Adverse Effects of Premedication for Reducing Pain and Discomfort during Fiberoptic Nasal Pharyngoscopy and Laryngoscopy Open
INTRODUCTION: Fiberoptic nasal endoscopy is a common procedure. Pretreatment with many drugs has been tried to decrease discomfort and pain related to the procedure. It was our effort to study whether they are effective in reducing pain an…
View article: Insomnia, its Prevalence, Associated Factors and Effects on Old Age: A Cross-Sectional Study
Insomnia, its Prevalence, Associated Factors and Effects on Old Age: A Cross-Sectional Study Open
Introduction: Insomnia is a common problem among old age population. Almost half of all old age adults report difficulty in initiating and maintaining sleep. The objective of this study was to assess the prevalence of insomnia, its associa…
View article: Effectiveness of Same-Day Human Ear Wax Removal as an Office Procedure and Factors Associated with its Successful Removal
Effectiveness of Same-Day Human Ear Wax Removal as an Office Procedure and Factors Associated with its Successful Removal Open
Introduction: There are various methods of ear wax extraction and there are no specific guidelines on this subject. Many times we ask patients to instil some wax softening product for a few days and revisit for wax removal. This revisits r…
View article: Essential Palatal Myoclonus
Essential Palatal Myoclonus Open
Introduction: Palatal myoclonus is a rare condition presenting with clicking sound in ear or muscle tremor in pharynx. There are two varieties: essential and symptomatic. Various treatment options exists ranging from watchful observation t…
View article: First Line Treatment of Meniere’s Disease
First Line Treatment of Meniere’s Disease Open
Introduction: There is no consensus on the first line medical treatment of Meniere disease to produce symptomatic improvement and slow the disease progress. Dietary salt restriction, diuretics, and vasodilators like betahistine are among t…
View article: Endoscopic Management of Epistaxis in Lumbini Medical College
Endoscopic Management of Epistaxis in Lumbini Medical College Open
Introduction: Epistaxis is one of the commonest Ear Nose Throat (ENT) emergency. Proper guidelines for its management are lacking; on the other hand, the management is mostly done by the junior health service providers which has invited no…