Anup Datta
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View article: Evaluation of Cholera Toxin B Subunit as a Novel Carrier Protein for Polysaccharide Conjugate Vaccines
Evaluation of Cholera Toxin B Subunit as a Novel Carrier Protein for Polysaccharide Conjugate Vaccines Open
Background: The immunogenicity of polysaccharide conjugate vaccines is critically influenced by the choice of carrier protein, which promotes a T-cell-dependent immune response mechanism leading to strong antibody production. In this study…
View article: Preclinical Immunogenicity of a 6-Valent GBS Glycoconjugate Vaccine from a Repeat-Dose GLP Toxicology Study
Preclinical Immunogenicity of a 6-Valent GBS Glycoconjugate Vaccine from a Repeat-Dose GLP Toxicology Study Open
Background/Objectives: Group B Streptococcus (GBS) is a significant cause of perinatal infection in neonates and infants. Complications could include neonatal sepsis and meningitis, preterm birth, stillbirth, or death. Though no GBS vaccin…
View article: The development of functional opsonophagocytic assays to evaluate antibody responses to <i>Klebsiella pneumoniae</i> capsular antigens
The development of functional opsonophagocytic assays to evaluate antibody responses to <i>Klebsiella pneumoniae</i> capsular antigens Open
Klebsiella pneumoniae is one of the leading causes of nosocomial infections in low- and middle-income countries (LMICs), with a high mortality rate among the immunocompromised. With increasing antibiotic resistance, there is an urgent need…
View article: SARS-CoV-2 conjugate vaccine elicits robust immune responses that can protect against evolving variants.
SARS-CoV-2 conjugate vaccine elicits robust immune responses that can protect against evolving variants. Open
View article: A rare case of complicated typhoid fever presenting with secondary Hemophagocytic Lymphohistiocytosis
A rare case of complicated typhoid fever presenting with secondary Hemophagocytic Lymphohistiocytosis Open
Enteric fever is one of the important causes of tropical fever with a prevalence of 11–21 million cases worldwide annually. It encompasses both typhoid and paratyphoid fever. Salmonella enterica Typhi is the causative organism for typhoid …
View article: Pulmonary thromboembolism—a rare presentation for Strongyloides hyperinfection in an immunocompetent patient
Pulmonary thromboembolism—a rare presentation for Strongyloides hyperinfection in an immunocompetent patient Open
Strongyloides stercoralis is an intestinal nematode. It is widely distributed in the tropics and sub-tropics of the world. It can cause a wide array of illnesses ranging from asymptomatic autoinfection to a severe form of hyperinfection an…
View article: Sars-Cov-2 Conjugate Vaccine Elicits Robust Immune Responses that Can Protect Against Evolving Variants
Sars-Cov-2 Conjugate Vaccine Elicits Robust Immune Responses that Can Protect Against Evolving Variants Open
View article: A rare presentation of dengue fever: bilateral psoas muscle hematoma, intrahepatic cholestatic hepatitis, pancreatitis and pancytopenia
A rare presentation of dengue fever: bilateral psoas muscle hematoma, intrahepatic cholestatic hepatitis, pancreatitis and pancytopenia Open
Dengue is the foremost cause of arthropod-borne viral disease in the world. It is and commonly found in tropical and subtropical parts of the world. Dengue fever is caused by one of the four distinct serotypes (DENV 1–4) of single-stranded…
View article: Disseminated Cryptococcosis in an Immunocompetent Patient: A Case Study
Disseminated Cryptococcosis in an Immunocompetent Patient: A Case Study Open
Cryptococcosis is the fungal infection caused by the yeast that belongs to the cryptococcus species which is divided into two broad categories, Cryptococcus neoformans and Cryptococcus gattii. Cryptococcosis is the opportunistic infection …
View article: Multi-valent pneumococcal conjugate vaccine for global health: From problem to platform to production
Multi-valent pneumococcal conjugate vaccine for global health: From problem to platform to production Open
Childhood bacterial meningitis and pneumonia represent leading causes of mortality, with the latter persisting as one of the top causes of mortality for children under 5 y of age. The prohibitive costs of developing and producing broader s…
View article: 32P Prosaposin A as a potential biomarker in patients of squamous cell carcinoma of head and neck
32P Prosaposin A as a potential biomarker in patients of squamous cell carcinoma of head and neck Open