Anup Kumar Thacker
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View article: Tongue tremor: A rare manifestation of disseminated central nervous system tuberculosis
Tongue tremor: A rare manifestation of disseminated central nervous system tuberculosis Open
Dear Sir, A 22-year-old man presented to us with a history suggestive of chronic meningitis in the form of fever and headache for the last 2 months along with occasional episodes of vomiting for the last 2 weeks. He had dysarthria for the …
View article: ALT and AST- New Prognostic Markers of COVID-19 in India
ALT and AST- New Prognostic Markers of COVID-19 in India Open
Introduction: The second wave of the COVID-19 pandemic has affected India ruthlessly, and high mortality has been observed in all age groups. The city of Lucknow was severely affected, and many patients were admitted to our hospital during…
View article: Gene Xpert MTB/RIF assay in patients with clinical suspicion of tuberculous meningitis
Gene Xpert MTB/RIF assay in patients with clinical suspicion of tuberculous meningitis Open
Early diagnosis and treatment of tubercular meningitis (TBM) is one of the best predictors of survival. The smear testing of the cerebrospinal fluid (CSF) has a low sensitivity and cultures, though having higher sensitivity, take a long ti…
View article: A Comparative Study of Regional Cerebral Blood Flow Asymmetry Index in Stroke Patients with or without Poststroke Depression Using 99mTc-ECD Single-Photon Emission Computed Tomography
A Comparative Study of Regional Cerebral Blood Flow Asymmetry Index in Stroke Patients with or without Poststroke Depression Using 99mTc-ECD Single-Photon Emission Computed Tomography Open
Introduction Stroke is a major cause of death and disability around the globe. The development of depression following a stroke further increases the disability and impairs functional recovery. In recent decades, despite the advancement in…
View article: Cranial Autonomic Symptoms in Migraine
Cranial Autonomic Symptoms in Migraine Open
Objective: Our aim was to observe frequency of cranial autonomic symptoms (CAS) in migraineurs (primary) and its relation with laterality of headache or other factors, if any. Background: Migraine episodes have headaches with or without au…
View article: Cranial autonomic symptoms in episodic migraine: An observational study from headache clinic of a tertiary care center of North India
Cranial autonomic symptoms in episodic migraine: An observational study from headache clinic of a tertiary care center of North India Open
Introduction: The presence of cranial autonomic symptoms (CAS) is a hallmark of trigeminal autonomic cephalalgia like cluster headache but their presence in migraine is also not uncommon. Like in trigeminal autonomic cephalalgias, the acti…
View article: High resolution ultrasonography of peripheral nerves in diabetic patients to evaluate nerve cross sectional area with clinical profile
High resolution ultrasonography of peripheral nerves in diabetic patients to evaluate nerve cross sectional area with clinical profile Open
Objectives: The aim of this observational study was ultrasound evaluation of peripheral nerves cross-sectional area (CSA) in subjects with probable diabetic peripheral sensorimotor neuropathy (DPN). CSA was analyzed with reference to clini…
View article: Malignant hyperthermia 2020
Malignant hyperthermia 2020 Open
Summary Malignant hyperthermia is defined in the International Classification of Diseases as a progressive life‐threatening hyperthermic reaction occurring during general anaesthesia. Malignant hyperthermia has an underlying genetic basis,…
View article: Radiofrequency Treatment of Idiopathic Trigeminal Neuralgia (Conventional vs. Pulsed)
Radiofrequency Treatment of Idiopathic Trigeminal Neuralgia (Conventional vs. Pulsed) Open
Background: Idiopathic trigeminal neuralgia (TGN) is a chronic pain disorder causing unilateral, severe brief stabbing recurrent pain in the distribution of one or more branches of the trigeminal nerve. Conventional radiofrequency (CRF) an…
View article: Clinical value of perilesional perfusion deficit measured by Technetium-99m-ECD single-photon emission computed tomography in hypertensive intracerebral hemorrhage
Clinical value of perilesional perfusion deficit measured by Technetium-99m-ECD single-photon emission computed tomography in hypertensive intracerebral hemorrhage Open
Pathological and experimental studies indicate the existence of a “penumbra” of progressive tissue damage and edema in regions immediately surrounding a hematoma in patients of intracerebral hemorrhage (ICH). This zone of oligemia surround…
View article: Diabetes mellitus type 2 impedes functional recovery, neuroplasticity and quality of life after stroke
Diabetes mellitus type 2 impedes functional recovery, neuroplasticity and quality of life after stroke Open
Diabetes is not only a risk factor for stroke occurrence but also delayed recovery after stroke.
View article: Depression impedes neuroplasticity and quality of life after stroke
Depression impedes neuroplasticity and quality of life after stroke Open
PSD is a serious complication, affecting quality of life and neuroplasticity (BDNF) in patients. Decreased neuroplasticity further may affect functional improvement.
View article: A2DS2 Score to Predict the Risk of Stroke-Associated Pneumonia in Acute Stroke: An Indian Perspective
A2DS2 Score to Predict the Risk of Stroke-Associated Pneumonia in Acute Stroke: An Indian Perspective Open
Background Stroke-associated pneumonia (SAP) is an important cause of poststroke morbidity and mortality. Several clinical risk scores predict the risk of SAP. In this study, we used the A2DS2 score (age, atrial fibrillation, dysphagia, se…
View article: Early PNF exercises functional outcome and quality in patients with stroke of urban and rural area in Uttar Pradesh: a prospective community based study
Early PNF exercises functional outcome and quality in patients with stroke of urban and rural area in Uttar Pradesh: a prospective community based study Open
Background: Early rehabilitation plays a very important role in stroke outcome. In India people from rural areas get primary treatment from district hospitals, where the rehabilitation facilities are not available, and then referred to the…
View article: Proprioceptive neuromuscular facilitation (PNF) vs. task specific training in acute stroke: the effects on neuroplasticity
Proprioceptive neuromuscular facilitation (PNF) vs. task specific training in acute stroke: the effects on neuroplasticity Open
\n\tObjectives:There are several approaches for rehabilitation of stroke patients. Proprioceptive Neuromuscular Facilitation (PNF) and Task Specific Training are the two approaches, known to promote motor learning and motor control. In th…
View article: Artery of percheron infarction: case reports and literature review
Artery of percheron infarction: case reports and literature review Open
The artery of Percheron is a rare anatomic variant supplying the thalamus and the rostral midbrain. Infarct in this territory results in a wide array of neurological signs and symptoms causing diagnostic dilemma and management issues. We d…
View article: Electrophysiological study of nerves in type-II reaction in leprosy
Electrophysiological study of nerves in type-II reaction in leprosy Open
In Type II lepra reaction the motor conduction abnormalities are not prominent. Abnormalities are relatively more marked in the proximal segment.
View article: Acute Encephalitis Syndrome in Adults and Its Correlation with Cytokine Levels in the Serum and Cerebrospinal Fluid
Acute Encephalitis Syndrome in Adults and Its Correlation with Cytokine Levels in the Serum and Cerebrospinal Fluid Open
Acute encephalitis syndrome (AES) is a major health problem in developing countries including India. Neuronal injury in encephalitis is attributed to direct toxicity from pathogens and proinflammatory cytokines. In this study, we assessed …
View article: Subacute Sclerosing Panencephalitis in a Child with Human Immunodeficiency Virus Co-Infection
Subacute Sclerosing Panencephalitis in a Child with Human Immunodeficiency Virus Co-Infection Open
Subacute sclerosing panencephalitis is a fatal infectious disease of childhood caused by persistence of the measles virus in the brain. The effect of human immunodeficiency virus (HIV) co-infection on subacute sclerosing panencephalitis re…
View article: Clinical features and predictors of in hospital mortality in patients with intra cerebral haemorrhage
Clinical features and predictors of in hospital mortality in patients with intra cerebral haemorrhage Open
Background: Intracerebral haemorrhage (ICH) accounts for 15-20% of all strokes and is associated with significant morbidity and mortality. The present study was done to assess the risk factors for ICH and determine the factors responsible …