Anupa A. Vijayakumari
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View article: Data-Driven Neurobiological Subtyping of Parkinson’s Disease Using Diffusion MRI-Derived Isotropic Diffusion
Data-Driven Neurobiological Subtyping of Parkinson’s Disease Using Diffusion MRI-Derived Isotropic Diffusion Open
Purpose Parkinson’s disease (PD) exhibits marked clinical and biological heterogeneity. This study aimed to identify neurobiologically defined PD subtypes using isotropic diffusion (ISO), a diffusion MRI metric sensitive to extracellular w…
View article: Evaluating an MRI-Based Machine Learning Classifier for Parkinson’s Progression Using Real-World Clinical Measures
Evaluating an MRI-Based Machine Learning Classifier for Parkinson’s Progression Using Real-World Clinical Measures Open
Background: Parkinson’s disease (PD) shows marked variability in disease progression, and predicting individual trajectories remains challenging. We previously developed a structural MRI–based machine learning classifier that distinguished…
View article: Author Correction: MRI-based multivariate gray matter volumetric distance for predicting motor symptom progression in Parkinson's disease
Author Correction: MRI-based multivariate gray matter volumetric distance for predicting motor symptom progression in Parkinson's disease Open
View article: MRI-based multivariate gray matter volumetric distance for predicting motor symptom progression in Parkinson's disease
MRI-based multivariate gray matter volumetric distance for predicting motor symptom progression in Parkinson's disease Open
While Parkinson's disease (PD)-related neurodegeneration is associated with structural changes in the brain, conventional magnetic resonance imaging (MRI) has proven less effective for clinical diagnosis due to its inability to reliably id…
View article: Can MRI-based multivariate gray matter volumetric distance predict motor progression and classify slow versus fast progressors in Parkinson’s disease?
Can MRI-based multivariate gray matter volumetric distance predict motor progression and classify slow versus fast progressors in Parkinson’s disease? Open
Introduction While Parkinson’s disease (PD) related neurodegeneration is associated with structural changes in the brain, magnetic resonance imaging (MRI) has not been helpful in diagnosing PD or predicting the progression of motor symptom…
View article: Tractography dissection variability: What happens when 42 groups dissect 14 white matter bundles on the same dataset?
Tractography dissection variability: What happens when 42 groups dissect 14 white matter bundles on the same dataset? Open
View article: Tractography-based targeting of ventral intermediate nucleus: A comparison between conventional stereotactic targeting and diffusion tensor imaging-based targeting
Tractography-based targeting of ventral intermediate nucleus: A comparison between conventional stereotactic targeting and diffusion tensor imaging-based targeting Open
Background The ventral intermediate (VIM) nucleus of the thalamus is the main target for lesioning using magnetic resonance imaging (MRI) guided focused ultrasound (MRgFUS) or deep brain stimulation (DBS). Targeting of VIM still depends on…
View article: Free Water Volume Fraction: An Imaging Biomarker to Characterize Moderate-to-Severe Traumatic Brain Injury
Free Water Volume Fraction: An Imaging Biomarker to Characterize Moderate-to-Severe Traumatic Brain Injury Open
Traumatic brain injury (TBI) is a major clinical and public health problem with few therapeutic interventions successfully translated to the clinic. Identifying imaging-based biomarkers characterizing injury severity and predicting long-te…
View article: Enhanced Fiber Tractography Using Edema Correction: Application and Evaluation in High-Grade Gliomas
Enhanced Fiber Tractography Using Edema Correction: Application and Evaluation in High-Grade Gliomas Open
BACKGROUND A limitation of diffusion tensor imaging (DTI)-based tractography is peritumoral edema that confounds traditional diffusion-based magnetic resonance metrics. OBJECTIVE To augment fiber-tracking through peritumoral regions by per…
View article: Tractography dissection variability: what happens when 42 groups dissect 14 white matter bundles on the same dataset?
Tractography dissection variability: what happens when 42 groups dissect 14 white matter bundles on the same dataset? Open
White matter bundle segmentation using diffusion MRI fiber tractography has become the method of choice to identify white matter fiber pathways in vivo in human brains. However, like other analyses of complex data, there is considerable va…
View article: Erratum: Figure Correction
Erratum: Figure Correction Open
[This corrects the article on p. 68 in vol. 13, PMID: 25912540.].
View article: A systematic examination of brain volumetric abnormalities in recent-onset schizophrenia using voxel-based, surface-based and region-of-interest-based morphometric analyses
A systematic examination of brain volumetric abnormalities in recent-onset schizophrenia using voxel-based, surface-based and region-of-interest-based morphometric analyses Open
View article: Effect of Polymorphisms of Three Genes Mediating Monoamine Signalling on Brain Morphometry in Schizophrenia and Healthy Subjects
Effect of Polymorphisms of Three Genes Mediating Monoamine Signalling on Brain Morphometry in Schizophrenia and Healthy Subjects Open
The findings of the present study have implications in understanding the role of individual and additive effects of genetic variants in mediating regional brain morphometry in health and disease.