Amrit Poudel
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View article: Optimization of Urban Traffic Flow: Capacity Analysis and Signal Timing Design at Pulchowk–Narayangadh
Optimization of Urban Traffic Flow: Capacity Analysis and Signal Timing Design at Pulchowk–Narayangadh Open
This study presents a comprehensive capacity analysis and signal timing design for the Pulchowk–Narayangadh intersection, a vital and heavily congested junction connecting key areas such as Gaidakot, Aaptari, Shahid Chowk, and Newroad in C…
View article: Assessment of Microbial Quality, Physiochemical Properties and Adulteration of Raw Milk in Pokhara
Assessment of Microbial Quality, Physiochemical Properties and Adulteration of Raw Milk in Pokhara Open
Objectives: This study was conducted to assess the microbial quality, physiochemical properties and adulteration status of raw milk collected from different farms of Lekhanath, Pokhara, Nepal. Methods: Total of 30 milk samples (15 Cow and …
View article: EntGPT: Entity Linking with Generative Large Language Models
EntGPT: Entity Linking with Generative Large Language Models Open
Entity Linking in natural language processing seeks to match text entities to their corresponding entries in a dictionary or knowledge base. Traditional approaches rely on contextual models, which can be complex, hard to train, and have li…
View article: Leveraging Transformer-based Language Models to Automate Requirements Satisfaction Assessment
Leveraging Transformer-based Language Models to Automate Requirements Satisfaction Assessment Open
Requirements Satisfaction Assessment (RSA) evaluates whether the set of design elements linked to a single requirement provide sufficient coverage of that requirement -- typically meaning that all concepts in the requirement are addressed …
View article: Cinnamomum verum extract inhibits NOX2/ROS and PKCδ/JNK/AP-1/NF-κB pathway-mediated inflammatory response in PMA-stimulated THP-1 monocytes
Cinnamomum verum extract inhibits NOX2/ROS and PKCδ/JNK/AP-1/NF-κB pathway-mediated inflammatory response in PMA-stimulated THP-1 monocytes Open
C. verum effectively inhibits inflammation and oxidative stress during monocyte-macrophage differentiation and downregulates inflammatory mediators via NOX2/ROS and PKCδ/JNK/AP-1/NF-κB signaling.
View article: Varietal Identification of Rice Seed Using Deep Convolutional Neural Network
Varietal Identification of Rice Seed Using Deep Convolutional Neural Network Open
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View article: Enhancing Automated Software Traceability by Transfer Learning from Open-World Data
Enhancing Automated Software Traceability by Transfer Learning from Open-World Data Open
Software requirements traceability is a critical component of the software engineering process, enabling activities such as requirements validation, compliance verification, and safety assurance. However, the cost and effort of manually cr…
View article: Study of Antibacterial Activity of Root Bark, Leaves, and Pericarp Extracts of Diploknema butyracea and Evaluation of Prospective Antioxidant Activity
Study of Antibacterial Activity of Root Bark, Leaves, and Pericarp Extracts of Diploknema butyracea and Evaluation of Prospective Antioxidant Activity Open
This study was aimed to determine the antibacterial activity of root bark, leaves, and pericarp extract of Diploknema butyracea and to evaluate the prospective antioxidant activity, total flavonoid, polyphenol, and carbohydrate content. Th…
View article: Pimarane Diterpenoids from Aerial Parts of Lycopus lucidus and Their Antimicrobial Activity
Pimarane Diterpenoids from Aerial Parts of Lycopus lucidus and Their Antimicrobial Activity Open
The ethyl acetate fraction obtained from aerial parts of L. lucidus was subjected for isolation of new bioactive compounds, which enabled isolation of five new pimarane-type diterpenoids, namely, 3β, 8β, 12β, 18-tetrahydroxy pimar-15-ene (…
View article: Evaluation of Anti-Obesity Activity of an Herbal Formulation (F2) in DIO Mice Model and Validation of UPLC-DAD Method for Quality Control
Evaluation of Anti-Obesity Activity of an Herbal Formulation (F2) in DIO Mice Model and Validation of UPLC-DAD Method for Quality Control Open
Obesity is considered a chronic metabolic disorder that can be associated with multiple medical complications. Currently, there is no or limited curative therapy for obesity. This study focused on the assessment of anti-obesity activity an…
View article: Estimation of Total Quercetin and Rutin Content in Malus domestica of Nepalese Origin by HPLC Method and Determination of Their Antioxidative Activity
Estimation of Total Quercetin and Rutin Content in Malus domestica of Nepalese Origin by HPLC Method and Determination of Their Antioxidative Activity Open
Malus domestica (Apple) is one of the most widely cultivated cash crops of Nepal. Jumla and Mustang are two major pocket areas for the production of apple. Flavonoids including quercetin and rutin are potent antioxidants present in apples.…
View article: Geographical Discrimination in Curcuminoids Content of Turmeric Assessed by Rapid UPLC-DAD Validated Analytical Method
Geographical Discrimination in Curcuminoids Content of Turmeric Assessed by Rapid UPLC-DAD Validated Analytical Method Open
A fast and reliable ultra-performance liquid chromatography-diode array detection method was developed and validated for the quantitative assessment of turmeric extracts from different geographical locations. Acclaim RSLC PolarAdvantage II…
View article: Constituents of Cryptotaenia japonica Inhibit Melanogenesis via CREB- and MAPK-Associated Signaling Pathways in Murine B16 Melanoma Cells
Constituents of Cryptotaenia japonica Inhibit Melanogenesis via CREB- and MAPK-Associated Signaling Pathways in Murine B16 Melanoma Cells Open
Melanin plays an important role in protecting the skin against ultraviolet light and is responsible for skin color. However, overproduction of melanin is related to several skin disorders, such as age spots, freckles, café au lait spots, B…
View article: Psychosocial problems among individuals with substance use disorders in drug rehabilitation centers, Nepal
Psychosocial problems among individuals with substance use disorders in drug rehabilitation centers, Nepal Open
View article: Development of UPLC Fingerprint with Multi-Component Quantitative Analysis for Quality Consistency Evaluation of Herbal Medicine “Hyangsapyeongwisan”
Development of UPLC Fingerprint with Multi-Component Quantitative Analysis for Quality Consistency Evaluation of Herbal Medicine “Hyangsapyeongwisan” Open
Hyangsapyeongwisan (HSPWS), known as traditional herbal medicine, has been used in the treatment of gastric disease. Standardization of HSPWS is a necessary step for the establishment of a consistent biological activity for the production …