A. P. Ray
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View article: Reactive Oxygen Detoxification Contributes to Mycobacterium abscessus Antibiotic Survival
Reactive Oxygen Detoxification Contributes to Mycobacterium abscessus Antibiotic Survival Open
When a population of bacteria encounter a bactericidal antibiotic most cells die rapidly. However, a sub-population, known as “persister cells”, can survive for prolonged periods in a non-growing, but viable, state. Persister cell frequenc…
View article: Reactive Oxygen Detoxification Contributes to Mycobacterium abscessus Antibiotic Survival
Reactive Oxygen Detoxification Contributes to Mycobacterium abscessus Antibiotic Survival Open
When a population of bacteria are exposed to a bactericidal antibiotic most cells die rapidly. However, a sub-population of antibiotic-tolerant cells known as “persister cells” can survive for prolonged periods, and antibiotic tolerance ca…
View article: Thrombin confers chemotherapeutic resistance by promoting transcriptional induction and post-translational stabilization of pro-survival MCL1 in TNBC
Thrombin confers chemotherapeutic resistance by promoting transcriptional induction and post-translational stabilization of pro-survival MCL1 in TNBC Open
The association between idiopathic venous thrombosis and occult cancer is widely recognized. However, the comprehensive understanding of how thrombin, generated during the process of thrombosis, possesses the potential to augment the malig…
View article: Reactive Oxygen Detoxification Contributes to <i>Mycobacterium abscessus</i> Antibiotic Survival
Reactive Oxygen Detoxification Contributes to <i>Mycobacterium abscessus</i> Antibiotic Survival Open
When a population of bacteria are exposed to a bactericidal antibiotic most cells die rapidly. However, a sub-population of antibiotic-tolerant cells known as “persister cells” can survive for prolonged periods, and antibiotic tolerance ca…
View article: The balance between antiviral and antibacterial responses during<i>M. tuberculosis</i>infection is regulated by the ubiquitin ligase CBL
The balance between antiviral and antibacterial responses during<i>M. tuberculosis</i>infection is regulated by the ubiquitin ligase CBL Open
As a first line of host defense, macrophages must be able to effectively sense and respond to diverse types of pathogens, and while a particular type of immune response may be beneficial in some circumstances, it can be detrimental in othe…