Amalesh Samanta
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View article: Development and Characterization of Calendula officinalis Extract-Loaded Topical Gels For Use In Inflammatory Skin Conditions Associated With Staphylococcus aureus and Pseudomonas aeruginosa in Diabetic Foot Ulcers
Development and Characterization of Calendula officinalis Extract-Loaded Topical Gels For Use In Inflammatory Skin Conditions Associated With Staphylococcus aureus and Pseudomonas aeruginosa in Diabetic Foot Ulcers Open
In order to treat bacterial skin infections linked to diabetic foot ulcers, the current study focusses on the creation and assessment of a topical herbal gel formulation including microwave-assisted Calendula officinalis leaf extract (COLE…
View article: Optimization of cold active amylase production by mesophilic Bacillus cereus RGUJS2023 under submerged fermentation
Optimization of cold active amylase production by mesophilic Bacillus cereus RGUJS2023 under submerged fermentation Open
Aim: To produce the highest amount of cold-active alpha-amylase within a short time using mesophilic bacteria with optimized media to save the energy consumption cost and obtain higher enzyme production. Methodology: Amylase producing twen…
View article: A review on fungal pullulan as a natural polymer focusing on targeted therapy for colon cancer and other pharmaceutical applications
A review on fungal pullulan as a natural polymer focusing on targeted therapy for colon cancer and other pharmaceutical applications Open
Colon cancer is the second most invasive cancer and fourth most common malignant neoplasm worldwide. Targeted oral colonic drug delivery systems have attracted considerable attention in the treatment of colon cancer due to their superior p…
View article: Correction: Anti-Inflammatory Activity of Odina wodier Roxb, an Indian Folk Remedy, through Inhibition of Toll-Like Receptor 4 Signaling Pathway
Correction: Anti-Inflammatory Activity of Odina wodier Roxb, an Indian Folk Remedy, through Inhibition of Toll-Like Receptor 4 Signaling Pathway Open
[This corrects the article DOI: 10.1371/journal.pone.0104939.].
View article: Real World Study of Effectiveness of Gemigliptin Add-On Therapy in Type 2 Diabetes Mellitus
Real World Study of Effectiveness of Gemigliptin Add-On Therapy in Type 2 Diabetes Mellitus Open
BACKGROUND: Dipeptidyl peptidase-4 (DPP-4) inhibitors are a new class of oral antidiabetic agents that increase endogenous levels of incretin hormones and lead to an increased insulin level and a reduced glucagon level in a glucose-depende…
View article: Partial Purification and Characterization of Albain 1, a Triterpene with Antimicrobial Activity, from the Wood Extract of Avicennia alba Blume
Partial Purification and Characterization of Albain 1, a Triterpene with Antimicrobial Activity, from the Wood Extract of Avicennia alba Blume Open
Secondary metabolites of plants are important resources for development of new drugs. Mangrove plants are very well known sources of wide variety of secondary metabolites. Many of these secondary metabolites from mangroves have been found …
View article: PHARMACOGNOSTIC STUDIES ON FLOWERS OF DREGEA VOLUBILIS: EVALUATION FOR AUTHENTICATION AND STANDARDIZATION
PHARMACOGNOSTIC STUDIES ON FLOWERS OF DREGEA VOLUBILIS: EVALUATION FOR AUTHENTICATION AND STANDARDIZATION Open
Objective: The various parts of Dregea volubilis (Family: Apocynaceae), locally known as Jukti (Bengali), are commonly used in Indian system of medicine to treat various ailments such as inflammation, piles, leukoderma, asthma, and tumors.…
View article: ANTIMICROBIAL INVESTIGATION AND BINDING MODE ANALYSIS OF SOME NEWLY SYNTHESIZED 4-AMINO-5-((ARYL SUBSTITUTED)-4H-1, 2, 4-TRIAZOLE-3-YL)-THIO LINKED HYDROXAMIC ACID DERIVATIVES
ANTIMICROBIAL INVESTIGATION AND BINDING MODE ANALYSIS OF SOME NEWLY SYNTHESIZED 4-AMINO-5-((ARYL SUBSTITUTED)-4H-1, 2, 4-TRIAZOLE-3-YL)-THIO LINKED HYDROXAMIC ACID DERIVATIVES Open
Objective: A series of 5-substituted-4-amino-1, 2, 4-triazole-linked hydroxamic acid derivatives have been synthesized and explored in vitro to evaluate antibacterial and antifungal activities.
Methods: Different 5-phenyl group substitute…
View article: Metabolite profiling and <i>in-vitro</i> colon cancer protective activity of <i>Cycas revoluta</i> cone extract
Metabolite profiling and <i>in-vitro</i> colon cancer protective activity of <i>Cycas revoluta</i> cone extract Open
The methanolic extract of Cycas revoluta cone (MECR) was analyzed by GC-MS and UHPLC for metabolite profiling and was evaluated for anti-colon cancer property by using in vitro assays like Cell Viability Assay, Colony Formation Assay, ROS …
View article: PREVENTIVE EFFECT OF CYCAS REVOLUTA IN 1,2-DIMETHYLHYDRAZINE-INDUCED COLON CANCER IN WISTAR RAT MODEL
PREVENTIVE EFFECT OF CYCAS REVOLUTA IN 1,2-DIMETHYLHYDRAZINE-INDUCED COLON CANCER IN WISTAR RAT MODEL Open
Objective: The aim of this study was to evaluate the colon cancer protective activity of Cycas revoluta (Cycadaceae).Methods: Methanolic extracts of C. revoluta (MECR) were assessed for total polyphenols and total flavonoids content. For t…
View article: Development of lamivudine containing multiple emulsions stabilized by gum odina
Development of lamivudine containing multiple emulsions stabilized by gum odina Open
In the current study, a multiple emulsion (W/O/W) of lamivudine was developed using a new biopolymer, gum odina (GOd) to increase bioavailability and patient compliances. GOd was employed to stabilize both the interfaces of liquid membrane…
View article: CCDC 1418614: Experimental Crystal Structure Determination
CCDC 1418614: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Vanadium(III)-<scp>l</scp>-cysteine enhances the sensitivity of murine breast adenocarcinoma cells to cyclophosphamide by promoting apoptosis and blocking angiogenesis
Vanadium(III)-<span>l</span>-cysteine enhances the sensitivity of murine breast adenocarcinoma cells to cyclophosphamide by promoting apoptosis and blocking angiogenesis Open
Various epidemiological and preclinical studies have already established the cancer chemopreventive potential of vanadium-based compounds. In addition to its preventive efficacy, studies have also indicated the abilities of vanadium-based …
View article: An investigation on heavy metal tolerance and antibiotic resistance properties of bacterial strain Bacillus sp. isolated from municipal waste
An investigation on heavy metal tolerance and antibiotic resistance properties of bacterial strain Bacillus sp. isolated from municipal waste Open
The objective of our present study was to isolate heavy metal tolerant and antibiotic resistant microorganisms, the site selected being the K.M.C.’s Waste Dumping Yard, Dhapa, Kolkata, West Bengal, India, based on the extent of pollutants …
View article: Ameliorative effects of pyrazinoic acid against oxidative and metabolic stress manifested in rats with dimethylhydrazine induced colonic carcinoma
Ameliorative effects of pyrazinoic acid against oxidative and metabolic stress manifested in rats with dimethylhydrazine induced colonic carcinoma Open
Pyrazinoic acid (PA) is structurally similar to nicotinic acid which acts on G-protein-coupled receptor (GPR109A). GPR109A expresses in colonic and intestinal epithelial sites, and involves in DNA methylation and cellular apoptosis. Theref…
View article: CCDC 1454986: Experimental Crystal Structure Determination
CCDC 1454986: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 903324: Experimental Crystal Structure Determination
CCDC 903324: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 903325: Experimental Crystal Structure Determination
CCDC 903325: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Gum odina: an emerging gut modulating approach in colorectal cancer prevention
Gum odina: an emerging gut modulating approach in colorectal cancer prevention Open
This study is focused on Gum Odina (GO), a reported prebiotic in our earlier work, and its impact on colorectal cancer (CRC).
View article: A new exploration of Dregea volubilis flowers: Focusing on antioxidant and antidiabetic properties
A new exploration of Dregea volubilis flowers: Focusing on antioxidant and antidiabetic properties Open
Flowers of Dregea volubilis (Family: Apocynaceae) are commonly consumed as seasonal vegetable in India but not yet evaluated for its health beneficiary effects. In the present study, the hydroalcoholic flower extract of D. volubilis (DVHA)…
View article: Ameliorative effect of an oxovanadium (IV) complex against oxidative stress and nephrotoxicity induced by cisplatin
Ameliorative effect of an oxovanadium (IV) complex against oxidative stress and nephrotoxicity induced by cisplatin Open
In this study, VC-IV exhibited strong nephroprotective efficacy by restoring antioxidant defense mechanisms and hence may serve as a promising chemoprotectant in cancer chemotherapy.
View article: Partial purification and characterization of an antimicrobial activity from the wood extract of mangrove plant Ceriops decandra
Partial purification and characterization of an antimicrobial activity from the wood extract of mangrove plant Ceriops decandra Open
The development of resistance towards the antibiotics in use today has been a source of growing concern in the modern healthcare system around the world. To counter this major threat, there is an urgent need for discovery of new antimicrob…
View article: Pedilanthus tithymaloides Inhibits HSV Infection by Modulating NF-κB Signaling
Pedilanthus tithymaloides Inhibits HSV Infection by Modulating NF-κB Signaling Open
Pedilanthus tithymaloides (PT), a widely used ethnomedicinal plant, has been employed to treat a number of skin conditions. To extend its utility and to fully exploit its medicinal potential, we have evaluated the in vitro antiviral activi…
View article: COMPARATIVE ANALYSIS OF PHYTOCONSTITUTIONAL AND PHARMACOLOGICAL ACTIVITIES OF DIFFERENT SEASONAL TEA LEAVES EXTRACTS
COMPARATIVE ANALYSIS OF PHYTOCONSTITUTIONAL AND PHARMACOLOGICAL ACTIVITIES OF DIFFERENT SEASONAL TEA LEAVES EXTRACTS Open
Methanolic extract of tea leaves (Camellia sinensis Linn.) of autumn and rain collections (SA and SR respectively) were investigated for in vitro antioxidants, antibacterial and wound healing activities to correlate with the impact of seas…