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View article: A Rare Neuroendocrine Tumor at the Junction of the Cystic and Common Hepatic Ducts: The Value of a Multimodal Approach in Preoperative Diagnosis
A Rare Neuroendocrine Tumor at the Junction of the Cystic and Common Hepatic Ducts: The Value of a Multimodal Approach in Preoperative Diagnosis Open
View article: A Case of High-Dose-Rate Brachytherapy Under Endoscopic Retrograde Cholangiopancreatography (ERCP) for Intraductal Papillary Neoplasm of the Bile Duct
A Case of High-Dose-Rate Brachytherapy Under Endoscopic Retrograde Cholangiopancreatography (ERCP) for Intraductal Papillary Neoplasm of the Bile Duct Open
Intraductal papillary neoplasm of the bile duct (IPNB) represents a relatively nascent pathological entity, recognized as a precancerous condition within the spectrum of cholangiocarcinoma. Surgical intervention is advocated for all patien…
View article: Clinicopathological Findings and Treatment Outcomes of Patients with Primary Hepatobiliary Neuroendocrine Neoplasms: A Retrospective Single-institution Analysis
Clinicopathological Findings and Treatment Outcomes of Patients with Primary Hepatobiliary Neuroendocrine Neoplasms: A Retrospective Single-institution Analysis Open
Objective Primary hepatobiliary neuroendocrine neoplasms (NENs) are rare tumors exhibiting several morphological and behavioral characteristics. Considering the lack of relevant data on this topic, we evaluated the clinicopathological feat…
View article: Indium chloride bone marrow scintigraphy for hepatic myelolipoma: A case report
Indium chloride bone marrow scintigraphy for hepatic myelolipoma: A case report Open
This is the first report on the diagnosis of hepatic myelolipoma using 111InCl3 scintigraphy. The effectiveness of bone marrow scintigraphy for diagnosing hepatic myelolipoma might be limited. As radiopharmaceuticals …
View article: Prevalence of Merkel Cell Polyomavirus in Primary Eyelid Merkel Cell Carcinomas and Association With Clinicopathological Features
Prevalence of Merkel Cell Polyomavirus in Primary Eyelid Merkel Cell Carcinomas and Association With Clinicopathological Features Open
Clinical and histopathological characteristics of 10 patients with eyelid MCC were elucidated. MCPyV infection was detected in all eyelids. These results provide insight for understanding the tumorigenesis of eyelid MCC.
View article: A deep learning model to detect pancreatic ductal adenocarcinoma on endoscopic ultrasound-guided fine-needle biopsy
A deep learning model to detect pancreatic ductal adenocarcinoma on endoscopic ultrasound-guided fine-needle biopsy Open
View article: The Diagnostic Utility of RAS Q61R Mutation-specific Immunohistochemistry in Epithelial-Myoepithelial Carcinoma
The Diagnostic Utility of RAS Q61R Mutation-specific Immunohistochemistry in Epithelial-Myoepithelial Carcinoma Open
Epithelial-myoepithelial carcinoma (EMC) is a rare salivary gland cancer characterized by biphasic tubular structures composed of inner ductal and outer clear myoepithelial cells. Because of its histologic variety and overlap of histologic…
View article: Sialadenoma Papilliferum of the Bronchus
Sialadenoma Papilliferum of the Bronchus Open
Sialadenoma papilliferum (SP) is a rare benign tumor of the salivary glands, and only 3 unequivocal cases of SP arising in the bronchus have been reported. We herein describe the histomorphologic and molecular features of 4 bronchial SP ca…
View article: Establishment of Patient-Derived Organoids and Drug Screening for Biliary Tract Carcinoma
Establishment of Patient-Derived Organoids and Drug Screening for Biliary Tract Carcinoma Open
Biliary tract carcinomas (BTCs) are among the most aggressive malignancies and have a poor prognosis. Here, we successfully established organoid lines derived from intrahepatic cholangiocarcinoma, gallbladder cancer, and neuroendocrine car…
View article: Feasibility and utility of a panel testing for 114 cancer‐associated genes in a clinical setting: A hospital‐based study
Feasibility and utility of a panel testing for 114 cancer‐associated genes in a clinical setting: A hospital‐based study Open
Next‐generation sequencing ( NGS ) of tumor tissue (ie, clinical sequencing) can guide clinical management by providing information about actionable gene aberrations that have diagnostic and therapeutic significance. Here, we undertook a h…
View article: Calcifying nested stromal epithelial tumor of the liver in a patient with Klinefelter syndrome: a case report and review of the literature
Calcifying nested stromal epithelial tumor of the liver in a patient with Klinefelter syndrome: a case report and review of the literature Open
This case suggests that an imbalance of hormones affects the genesis and progression of CNSET, and indicates the importance of closely following patients with CNSET by imaging with attention to hepatic recurrence and extrahepatic metastase…
View article: Induction of differentiation of intrahepatic cholangiocarcinoma cells to functional hepatocytes using an organoid culture system
Induction of differentiation of intrahepatic cholangiocarcinoma cells to functional hepatocytes using an organoid culture system Open
View article: SOX10 Expression as Well as <i>BRAF</i> and <i>GNAQ/11</i> Mutations Distinguish Pigmented Ciliary Epithelium Neoplasms From Uveal Melanomas
SOX10 Expression as Well as <i>BRAF</i> and <i>GNAQ/11</i> Mutations Distinguish Pigmented Ciliary Epithelium Neoplasms From Uveal Melanomas Open
APCE is a separate entity distinguished from UM by the absence of SOX10 expression and presence of the BRAF V600E mutation. These results have implications for diagnosis, providing a means to distinguish between UM and APCE.
View article: Prognostic Impact of Margin Distance and Tumor Spread Through Air Spaces in Limited Resection for Primary Lung Cancer
Prognostic Impact of Margin Distance and Tumor Spread Through Air Spaces in Limited Resection for Primary Lung Cancer Open
View article: Genome-wide DNA methylation analysis during non-alcoholic steatohepatitis-related multistage hepatocarcinogenesis: comparison with hepatitis virus-related carcinogenesis
Genome-wide DNA methylation analysis during non-alcoholic steatohepatitis-related multistage hepatocarcinogenesis: comparison with hepatitis virus-related carcinogenesis Open
The aim of this study was to clarify the significance of DNA methylation alterations during non-alcoholic steatohepatitis (NASH)-related hepatocarcinogenesis. Single-CpG-resolution genome-wide DNA methylation analysis was performed on 264 …
View article: P3.01-015 Prognostic Impact of Histologic Invasion Factors in Pulmonary Adenocarcinoma, with Particular Focus on the Pattern of Architectural Remodeling
P3.01-015 Prognostic Impact of Histologic Invasion Factors in Pulmonary Adenocarcinoma, with Particular Focus on the Pattern of Architectural Remodeling Open
View article: A Case of Intramucosal Gastric Cancer Partly Containing Poorly Differentiated Adenocarcinoma Component with Neuroendocrine Features
A Case of Intramucosal Gastric Cancer Partly Containing Poorly Differentiated Adenocarcinoma Component with Neuroendocrine Features Open
An 81-year-old man underwent esophagogastroduodenoscopy, and a 30-mm elevated-type lesion was identified at the greater curvature of the lower gastric body. There were no signs of submucosal invasion. Biopsy specimens revealed moderately d…