Aoife J McCarthy
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View article: A Case Series of Extrafacial Granuloma Faciale
A Case Series of Extrafacial Granuloma Faciale Open
View article: P27: INTRODUCTION OF A PILOT VIRTUAL FRACTURE CLINIC: A TIME AND COST ANALYSIS
P27: INTRODUCTION OF A PILOT VIRTUAL FRACTURE CLINIC: A TIME AND COST ANALYSIS Open
Introduction The British Orthopaedic Association Standards for Trauma and Orthopaedics(BOAST) have produced guidelines advising that all patients be reviewed by an orthopaedic consultant within 72 hours of presentation. However, data from …
View article: Applications of Circulating Tumor DNA in a Cohort of Phase I Solid Tumor Patients Treated With Immunotherapy
Applications of Circulating Tumor DNA in a Cohort of Phase I Solid Tumor Patients Treated With Immunotherapy Open
Background The correlation between blood-based tumor mutation burden (bTMB) and tissue-based tumor mutation burden(tTMB) has not been broadly tested in a multicancer cohort. Here, we assess the correlation between bTMB with tTMB in phase I…
View article: Traditional serrated adenoma: an overview of pathology and emphasis on molecular pathogenesis
Traditional serrated adenoma: an overview of pathology and emphasis on molecular pathogenesis Open
Objective To provide an overview of the pathology and molecular pathogenesis of traditional serrated adenomas (TSA). Design Describe the morphology and molecules that play a role in their pathogenesis. Results These exuberant polypoid lesi…
View article: Metastatic low-grade endometrial stromal sarcoma of uterus presenting as a primary pancreatic tumor: case presentation and literature review
Metastatic low-grade endometrial stromal sarcoma of uterus presenting as a primary pancreatic tumor: case presentation and literature review Open
View article: Colorectal Serrated Neoplasia: An Institutional 12-Year Review Highlights the Impact of a Screening Programme
Colorectal Serrated Neoplasia: An Institutional 12-Year Review Highlights the Impact of a Screening Programme Open
Background . As the malignant potential of sessile serrated lesions/polyps (SSL/Ps) and traditional serrated adenomas (TSAs) has been clearly demonstrated, it is important that serrated polyps are identified and correctly classified histol…
View article: Gut-associated lymphoid tissue or so-called “dome” carcinoma of the colon: Review
Gut-associated lymphoid tissue or so-called “dome” carcinoma of the colon: Review Open
Increased awareness amongst histopathologists of this variant of colorectal adenocarcinoma is likely to lead to the recognition of more cases.
View article: Heterogenous loss of mismatch repair (MMR) protein expression: a challenge for immunohistochemical interpretation and microsatellite instability (MSI) evaluation
Heterogenous loss of mismatch repair (MMR) protein expression: a challenge for immunohistochemical interpretation and microsatellite instability (MSI) evaluation Open
Immunohistochemistry (IHC) for mismatch repair (MMR) proteins is used to identify MMR status: being diffusely positive (intact/retained nuclear staining) or showing loss of nuclear tumour staining (MMR protein deficient). Four colonic aden…
View article: Primary low-grade fibromyxoid sarcoma of the large intestine with lung metastases: A case report and review of the literature
Primary low-grade fibromyxoid sarcoma of the large intestine with lung metastases: A case report and review of the literature Open
A 70-year old man had multiple lung nodules detected on a computed tomography (CT) performed as part of the work-up for an isolated episode of hematuria of several hours' duration. A CT-guided lung biopsy disclosed a morphologically undiff…
View article: Benign Smooth Muscle Tumors (Leiomyomas) of Deep Somatic Soft Tissue
Benign Smooth Muscle Tumors (Leiomyomas) of Deep Somatic Soft Tissue Open
Leiomyomas of deep soft tissue are extremely rare and should only be diagnosed following adherence to stringent histological criteria, namely, the absence of nuclear atypia and of coagulative tumor necrosis. Whether extremely low counts of…
View article: AB023. 209. Assessment of tumour budding in pre-treatment biopsies and its impact on outcomes in locally advanced rectal cancer patients
AB023. 209. Assessment of tumour budding in pre-treatment biopsies and its impact on outcomes in locally advanced rectal cancer patients Open
View article: Neural and neurogenic tumours of the gastroenteropancreaticobiliary tract
Neural and neurogenic tumours of the gastroenteropancreaticobiliary tract Open
Neural lesions occur uncommonly in the gastroenteropancreaticobiliary tract. However, due to the growing number of screening colonoscopy procedures, polypoid neural lesions of the colon are being recognised increasingly and range from beni…
View article: Tumours composed of fat are no longer a simple diagnosis: an overview of fatty tumours with a spindle cell component
Tumours composed of fat are no longer a simple diagnosis: an overview of fatty tumours with a spindle cell component Open
This is a review of the morphological spectrum of fatty tumours containing a component of spindle cells, highlighting the immunohistochemical and cytogenetic workup that is now mandatory for accurate diagnosis, with the goal of providing a…