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View article: Spatial Transcriptomics Identify T Cell-Driven Mechanisms of Kidney Damage in Immune Checkpoint Inhibitor-Associated Acute Interstitial Nephritis
Spatial Transcriptomics Identify T Cell-Driven Mechanisms of Kidney Damage in Immune Checkpoint Inhibitor-Associated Acute Interstitial Nephritis Open
Introduction: Immune checkpoint inhibitor-associated acute interstitial nephritis (ICI-AIN) is the most common finding on histopathology among patients with ICI-associated acute kidney injury (ICI-AKI). Patients with ICI-AIN often have T c…
View article: Ten tips on how to deal with calciphylaxis patients
Ten tips on how to deal with calciphylaxis patients Open
Calciphylaxis is a devastating disease characterized by painful ischemic necrotic skin lesions, primarily affecting patients with end-stage kidney disease. Its incidence has significantly increased over the past decade. Despite substantial…
View article: The Effect of Randomized Beta-Carotene Supplementation on CKD in Men
The Effect of Randomized Beta-Carotene Supplementation on CKD in Men Open
View article: The effect of levocarnitine supplementation on dialysis-related hypotension: A systematic review, meta-analysis, and trial sequential analysis
The effect of levocarnitine supplementation on dialysis-related hypotension: A systematic review, meta-analysis, and trial sequential analysis Open
Background Dialysis patients have been shown to have low serum carnitine due to poor nutrition, deprivation of endogenous synthesis from kidneys, and removal by hemodialysis. Carnitine deficiency leads to impaired cardiac function and dial…
View article: The association between olfactory and gustatory dysfunction and chronic kidney disease
The association between olfactory and gustatory dysfunction and chronic kidney disease Open
View article: Comparison of invasive treatment strategies in patients with non–ST elevation acute coronary syndrome: A systematic review and meta-analysis
Comparison of invasive treatment strategies in patients with non–ST elevation acute coronary syndrome: A systematic review and meta-analysis Open
OBJECTIVE: To compare the mortality associated with percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) in patients with non–ST elevation acute coronary syndrome (NSTE-ACS). METHODS: We searched publications…
View article: Outcomes of Kidney Transplant Recipients with Sickle Cell Disease: An Analysis of the 2000–2019 UNOS/OPTN Database
Outcomes of Kidney Transplant Recipients with Sickle Cell Disease: An Analysis of the 2000–2019 UNOS/OPTN Database Open
Background: Lower patient survival has been observed in sickle cell disease (SCD) patients who go on to receive a kidney transplant. This study aimed to assess the post-transplant outcomes of SCD kidney transplant recipients in the contemp…
View article: Risk of Symptomatic Kidney Stones During and After Pregnancy
Risk of Symptomatic Kidney Stones During and After Pregnancy Open
View article: Efficacy and Safety of SGLT-2 Inhibitors for Treatment of Diabetes Mellitus among Kidney Transplant Patients: A Systematic Review and Meta-Analysis
Efficacy and Safety of SGLT-2 Inhibitors for Treatment of Diabetes Mellitus among Kidney Transplant Patients: A Systematic Review and Meta-Analysis Open
Background: The objective of this systematic review was to evaluate the efficacy and safety profiles of sodium-glucose co-transporter 2 (SGLT-2) inhibitors for treatment of diabetes mellitus (DM) among kidney transplant patients. Methods: …
View article: Zika Virus Disease Comparing Children and Adults in a Dengue-Endemic Setting
Zika Virus Disease Comparing Children and Adults in a Dengue-Endemic Setting Open
Acute Zika virus (ZIKV) infection may mimic dengue virus (DENV) infection. We aimed to study the clinical difference of ZIKV disease among suspected non-severe DENV patients comparing children and adults. Patients with acute illness suspec…
View article: Phase-3 Randomized Controlled Trials on Exclusion of Participants With Kidney Disease in COVID-19
Phase-3 Randomized Controlled Trials on Exclusion of Participants With Kidney Disease in COVID-19 Open
Severe acute respiratory syndrome coronavirus 2, the virus that causes coronavirus disease 2019 (COVID-19), has a range of presentations and outcomes from asymptomatic carriage to acute respiratory distress syndrome and death.1Harapan H. I…
View article: Treatment of C3 Glomerulopathy in Adult Kidney Transplant Recipients: A Systematic Review
Treatment of C3 Glomerulopathy in Adult Kidney Transplant Recipients: A Systematic Review Open
Background: C3 glomerulopathy (C3G), a rare glomerular disease mediated by alternative complement pathway dysregulation, is associated with a high rate of recurrence and graft loss after kidney transplantation (KTx). We aimed to assess the…
View article: Impact of serum phosphate changes on in-hospital mortality
Impact of serum phosphate changes on in-hospital mortality Open
View article: Hospital-Acquired Dysmagnesemia and In-Hospital Mortality
Hospital-Acquired Dysmagnesemia and In-Hospital Mortality Open
Background and Objectives: This study aimed to report the incidence of hospital-acquired dysmagnesemia and its association with in-hospital mortality in adult general hospitalized patients. Materials and Methods: We studied 26,020 adult ho…
View article: SGLT2 Inhibitors and Kidney Outcomes in Patients with Chronic Kidney Disease
SGLT2 Inhibitors and Kidney Outcomes in Patients with Chronic Kidney Disease Open
Globally, diabetes mellitus is a leading cause of kidney disease, with a critical percent of patients approaching end-stage kidney disease. In the current era, sodium-glucose co-transporter 2 inhibitors (SGLT2i) have emerged as phenomenal …
View article: Vitamin D supplement on prevention of fall and fracture
Vitamin D supplement on prevention of fall and fracture Open
Background: Vitamin D supplement is one of the current possible interventions to reduce fall and fracture. Despite having several studies on vitamin D supplement and fall and fracture reductions, the results are still inconclusive. We cond…
View article: Impact of admission serum ionized calcium levels on risk of acute kidney injury in hospitalized patients
Impact of admission serum ionized calcium levels on risk of acute kidney injury in hospitalized patients Open
View article: Impact of Acute Kidney Injury on Outcomes of Hospitalizations for Heat Stroke in the United States
Impact of Acute Kidney Injury on Outcomes of Hospitalizations for Heat Stroke in the United States Open
This study aims to evaluate the risk factors and the association of acute kidney injury with treatments, complications, outcomes, and resource utilization in patients hospitalized for heat stroke in the United States. Hospitalized patients…
View article: Hospital-Acquired Serum Chloride Derangements and Associated In-Hospital Mortality
Hospital-Acquired Serum Chloride Derangements and Associated In-Hospital Mortality Open
Background: We aimed to describe the incidence of hospital-acquired dyschloremia and its association with in-hospital mortality in general hospitalized patients. Methods: All hospitalized patients from 2009 to 2013 who had normal admission…
View article: Circulatory Failure among Hospitalizations for Heatstroke in the United States
Circulatory Failure among Hospitalizations for Heatstroke in the United States Open
Background: This study aimed to assess the risk factors and the association of circulatory failure with treatments, complications, outcomes, and resource utilization in hospitalized patients for heatstroke in the United States. Methods: Ho…
View article: Serum Klotho in Living Kidney Donors and Kidney Transplant Recipients: A Meta-Analysis
Serum Klotho in Living Kidney Donors and Kidney Transplant Recipients: A Meta-Analysis Open
α-Klotho is a known anti-aging protein that exerts diverse physiological effects, including phosphate homeostasis. Klotho expression occurs predominantly in the kidney and is significantly decreased in patients with chronic kidney disease.…
View article: Serum Chloride Levels at Hospital Discharge and One-Year Mortality among Hospitalized Patients
Serum Chloride Levels at Hospital Discharge and One-Year Mortality among Hospitalized Patients Open
This study aimed to assess the one-year mortality risk based on discharge serum chloride among the hospital survivors. We analyzed a cohort of adult hospital survivors at a tertiary referral hospital from 2011 through 2013. We categorized …
View article: Degree of Glomerulosclerosis in Procurement Kidney Biopsies from Marginal Donor Kidneys and Their Implications in Predicting Graft Outcomes
Degree of Glomerulosclerosis in Procurement Kidney Biopsies from Marginal Donor Kidneys and Their Implications in Predicting Graft Outcomes Open
Background: This study aimed to assess the association between the percentage of glomerulosclerosis (GS) in procurement allograft biopsies from high-risk deceased donor and graft outcomes in kidney transplant recipients. Methods: The UNOS …
View article: Serum Potassium Levels at Hospital Discharge and One-Year Mortality among Hospitalized Patients
Serum Potassium Levels at Hospital Discharge and One-Year Mortality among Hospitalized Patients Open
Background and Objectives: The optimal range of serum potassium at hospital discharge is unclear. The aim of this study was to assess the relationship between discharge serum potassium levels and one-year mortality in hospitalized patients…
View article: Acute Myocardial Infarction among Hospitalizations for Heat Stroke in the United States
Acute Myocardial Infarction among Hospitalizations for Heat Stroke in the United States Open
Background: This study aimed to assess the risk factors and impact of acute myocardial infarction on in-hospital treatments, complications, outcomes, and resource utilization in hospitalized patients for heat stroke in the United States. M…
View article: Promises of Big Data and Artificial Intelligence in Nephrology and Transplantation
Promises of Big Data and Artificial Intelligence in Nephrology and Transplantation Open
Kidney diseases form part of the major health burdens experienced all over the world. Kidney diseases are linked to high economic burden, deaths, and morbidity rates. The great importance of collecting a large quantity of health-related da…
View article: Trajectories of Serum Sodium on In-Hospital and 1-Year Survival among Hospitalized Patients
Trajectories of Serum Sodium on In-Hospital and 1-Year Survival among Hospitalized Patients Open
Background and objectives This study aimed to investigate the association between in-hospital trajectories of serum sodium and risk of in-hospital and 1-year mortality in patients in hospital. Design, setting, participants, & measurements …
View article: Impact of Changes in Serum Calcium Levels on In-Hospital Mortality
Impact of Changes in Serum Calcium Levels on In-Hospital Mortality Open
Background and objectives: Calcium concentration is strictly regulated at both the cellular and systemic level, and changes in serum calcium levels can alter various physiological functions in various organs. This study aimed to assess the…
View article: Serum ionised calcium and the risk of acute respiratory failure in hospitalised patients: a single-centre cohort study in the USA
Serum ionised calcium and the risk of acute respiratory failure in hospitalised patients: a single-centre cohort study in the USA Open
Objectives The objective of this study was to evaluate the risk of acute respiratory failure in all hospitalised patients based on admission serum ionised calcium. Design A retrospective cohort study. Setting A tertiary referral hospital i…
View article: The effects of omega-3 fatty acids on diabetic nephropathy: A meta-analysis of randomized controlled trials
The effects of omega-3 fatty acids on diabetic nephropathy: A meta-analysis of randomized controlled trials Open
Omega-3 fatty acids could help ameliorate proteinuria among type 2 DM who received omega-3 supplementation for at least 24 weeks without adverse effects on HbA1C, total serum cholesterol and LDL-cholesterol.