Apoorva H. Nagendra
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View article: Macrophage-derived Spp1 promotes intramuscular fat in dystrophic muscle
Macrophage-derived Spp1 promotes intramuscular fat in dystrophic muscle Open
Duchenne muscular dystrophy (DMD) is a progressive muscle wasting disorder involving cycles of muscle degeneration and regeneration, leading to accumulation of intramuscular fibrosis and fat. Ablation of Osteopontin/Spp1 in a murine model …
View article: Sodium fluoride induces skeletal muscle atrophy via changes in mitochondrial and sarcomeric proteomes
Sodium fluoride induces skeletal muscle atrophy via changes in mitochondrial and sarcomeric proteomes Open
Sodium Fluoride (NaF) can change the expression of skeletal muscle proteins. Since skeletal muscle is rich in mitochondrial and contractile (sarcomeric) proteins, these proteins are sensitive to the effects of NaF, and the changes are dose…