Apurva Rustagi
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View article: Deep Learning in Drug Repurposing: A Review of the CoV-DrugX Module within the CoV-DrugX Pipeline
Deep Learning in Drug Repurposing: A Review of the CoV-DrugX Module within the CoV-DrugX Pipeline Open
A comprehensive overview of the integration of deep learning techniques in drug repurposing, particularly focusing on the CoV-DrugX module within the CoV-DrugX Pipeline. The paper highlights the significance of drug repurposing in accelera…
View article: AI-Driven Drug Repurposing for COVID-19: Revolutionizing Therapeutic Discovery and Treatment Strategies
AI-Driven Drug Repurposing for COVID-19: Revolutionizing Therapeutic Discovery and Treatment Strategies Open
In March of 2020, a deadly disaster caused a global pandemic all across the globe. This paper elucidates the concept of drug repurposing, a strategy that harnesses existing drugs for new therapeutic purposes. Leveraging drugs already appro…
View article: Symptom-Based Prediction Methods in Drug Repurposing for COVID-19 using CoVDrugX
Symptom-Based Prediction Methods in Drug Repurposing for COVID-19 using CoVDrugX Open
The validation study underscores the effectiveness of repurposed drugs in treating COVID-19symptoms, indicating their potential to alleviate symptom severity and duration. Understandingthe mechanisms of action behind these drugs' efficacy …
View article: Programmable antivirals targeting critical conserved viral RNA secondary structures from influenza A virus and SARS-CoV-2
Programmable antivirals targeting critical conserved viral RNA secondary structures from influenza A virus and SARS-CoV-2 Open
Influenza A virus’s (IAV’s) frequent genetic changes challenge vaccine strategies and engender resistance to current drugs. We sought to identify conserved and essential RNA secondary structures within IAV’s genome that are predicted to ha…
View article: Genome-wide bidirectional CRISPR screens identify mucins as host factors modulating SARS-CoV-2 infection
Genome-wide bidirectional CRISPR screens identify mucins as host factors modulating SARS-CoV-2 infection Open
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes a range of symptoms in infected individuals, from mild respiratory illness to acute respiratory distress syndrome. A systematic understanding of host factors influencing v…