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View article: Autoantibodies in long COVID in a black/mixed population compared with recovered and pre-pandemic controls
Autoantibodies in long COVID in a black/mixed population compared with recovered and pre-pandemic controls Open
Introduction Long COVID (LC), a clinical condition marked by persistent and new symptoms after infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), affects up to 10-20% of infected individuals. Although autoimmunity…
View article: Development and Validation of ELISA for In Vitro Diagnosis of SARS-CoV-2 Infection
Development and Validation of ELISA for In Vitro Diagnosis of SARS-CoV-2 Infection Open
(1) Background: The ongoing global health threat posed by SARS-CoV-2 requires reliable and accessible diagnostic tools, especially in resource-limited settings where RT-qPCR may be impractical. This study describes the development and vali…
View article: Comprehensive Study of the IBMP ELISA IgA/IgM/IgG COVID-19 Kit for SARS-CoV-2 Antibody Detection
Comprehensive Study of the IBMP ELISA IgA/IgM/IgG COVID-19 Kit for SARS-CoV-2 Antibody Detection Open
COVID-19 laboratory diagnosis primarily relies on molecular tests, highly sensitive during early infection stages with high viral loads. As the disease progresses, sensitivity decreases, requiring antibody detection. Since the beginning of…
View article: Effects of the Use of Beta-Blockers on Chronic Obstructive Pulmonary Disease Associated with Cardiovascular Comorbities: Systematic Review and Meta-analysis
Effects of the Use of Beta-Blockers on Chronic Obstructive Pulmonary Disease Associated with Cardiovascular Comorbities: Systematic Review and Meta-analysis Open
Cardiovascular comorbidity is common in individuals with chronic obstructive pulmonary disease (COPD). This factor interferes with pharmacological treatment. The use of β-blockers has been proposed for their known cardioprotective effects.…
View article: Usefulness of receptor binding domain protein-based serodiagnosis of COVID-19
Usefulness of receptor binding domain protein-based serodiagnosis of COVID-19 Open
This research underscores the potential of RBD-based ELISAs for COVID-19 diagnosis, especially when assessing samples collected 15-21 days post-symptom onset and utilizing a parallel testing approach. The RBD protein's immunogenicity and s…
View article: Metabolic disorders and post-acute hospitalization in black/mixed-race patients with long COVID in Brazil: A cross-sectional analysis
Metabolic disorders and post-acute hospitalization in black/mixed-race patients with long COVID in Brazil: A cross-sectional analysis Open
Background Although low-middle income countries have been disproportionately affected by the COVID-19 pandemic, there is scarce information about the impact of long COVID on their population. This study aimed to evaluate long COVID symptom…
View article: Prevalence and Impact of Comorbidities in Individuals with Chronic Obstructive Pulmonary Disease: A Systematic Review
Prevalence and Impact of Comorbidities in Individuals with Chronic Obstructive Pulmonary Disease: A Systematic Review Open
This study aimed to describe the prevalence of comorbidities associated with chronic obstructive pulmonary disease (COPD) and their relation with relevant outcomes. A systematic review based on the PRISMA methodology was performed from Jan…
View article: Urinary incontinence associated with pharmacological treatment of Chronic Obstructive Lung Disease: An integrative review
Urinary incontinence associated with pharmacological treatment of Chronic Obstructive Lung Disease: An integrative review Open
Chronic Obstructive Pulmonary Disease (COPD) is a lung disease, often associated with smoking. COPD patients have persistent, including urinary incontinence. Therefore, a research has the general objective of knowing the physiological mech…
View article: Post-Acute COVID Syndrome, the Aftermath of Mild to Severe COVID-19 in Brazilian Patients
Post-Acute COVID Syndrome, the Aftermath of Mild to Severe COVID-19 in Brazilian Patients Open
Objective To describe persistent symptoms after acute COVID-19 in different spectrum of disease severity in a population from an upper/middle income country, and identify the main clinical features impacting the quality of life. Design Cro…
View article: Is there is an association between mass and skeletal muscle strength in hospitalized elderly persons?
Is there is an association between mass and skeletal muscle strength in hospitalized elderly persons? Open
Introduction: The variables mass and skeletal muscle strength contribute to the diagnosis of sarcopenia. Objective: To evaluate the association between strength and skeletal muscle mass in hospitalized elderly persons. Method: A cross-sect…
View article: Home physical exercise improves functional mobility and quality of life in elderly. A CONSORT-prospective, randomized controlled clinical trial.
Home physical exercise improves functional mobility and quality of life in elderly. A CONSORT-prospective, randomized controlled clinical trial. Open
Aims: to test the hypothesis that a semi-supervised home physical exercise program improves the functional mobility and quality of life (QOL) of elderly in the community. Methods: This trial was conducted with elderly people (88% female), …
View article: Association of sleep quality with excessive daytime somnolence and quality of life of elderlies of community
Association of sleep quality with excessive daytime somnolence and quality of life of elderlies of community Open
Background: The progressive increase in the elderly population contributes to the fact that studies on human aging have important attention of health professionals and government agents, since they present a great challenge regarding publi…
View article: The effect of home-based exercise in sleep quality and excessive daytime sleepiness in elderly people: A protocol of randomized controlled clinical trial
The effect of home-based exercise in sleep quality and excessive daytime sleepiness in elderly people: A protocol of randomized controlled clinical trial Open
Background: Sleep-disordered breathing is associated with significant morbidity and mortality, presenting a high prevalence in the general population and being considered today as an important public health problem worldwide, affecting abo…
View article: Association of sleep quality with excessive daytime somnolence and quality of life of elderlies of community
Association of sleep quality with excessive daytime somnolence and quality of life of elderlies of community Open
The results of the present study allowed to identify a sleep quality associated with excessive daytime somnolence and quality of life and also to characterize the profile of elders with poor sleep quality.
View article: Home exercise improves the quality of sleep and daytime sleepiness of elderlies: a randomized controlled trial
Home exercise improves the quality of sleep and daytime sleepiness of elderlies: a randomized controlled trial Open
Background: Aging causes physiological changes which affect the quality of sleep. Supervised physical exercise is an important therapeutic resource to improve the sleep of the elderlies, however there is a low adherence to those type of pr…
View article: Home exercise improves the quality of sleep and daytime sleepiness of elderlies: a randomized controlled trial
Home exercise improves the quality of sleep and daytime sleepiness of elderlies: a randomized controlled trial Open
Ensaiosclinicos.gov.br process number: RBR-3cqzfy.
View article: Recommendations for the pharmacological treatment of COPD: questions and answers
Recommendations for the pharmacological treatment of COPD: questions and answers Open
The treatment of COPD has become increasingly effective. Measures that range from behavioral changes, reduction in exposure to risk factors, education about the disease and its course, rehabilitation, oxygen therapy, management of comorbid…
View article: PHYSICAL ACTIVITY LEVEL, FUNCTIONAL MOBILITY AND FALL RISK IN THE ELDERLY
PHYSICAL ACTIVITY LEVEL, FUNCTIONAL MOBILITY AND FALL RISK IN THE ELDERLY Open
Introduction: Low levels of physical activity and functional mobility lead to greater difficulty in performing activities of daily living and are directly proportional to mortality in the elderly. Thus, there are the need to create mechani…
View article: Inflammatory and immunological profiles in patients with COPD: relationship with FEV 1 reversibility
Inflammatory and immunological profiles in patients with COPD: relationship with FEV 1 reversibility Open
Objective: To determine whether COPD severity correlates with sputum cell counts, atopy, and asthma. Methods: This was a cross-sectional study involving 37 patients with COPD and 22 healthy subjects with normal lung function (controls). Sp…
View article: Viability of gait speed test in hospitalized elderly patients
Viability of gait speed test in hospitalized elderly patients Open
Objective: The gait speed test (GST) is a physical test that can predict falls and aid in the diagnosis of sarcopenia in the elderly. However, to our knowledge, there have been no studies evaluating its reproducibility in hospitalized elde…