A.R. Brooks
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Nuclease-hypersensitive sites define a region with enhancer activity in the third intron of the human apolipoprotein B gene. Open
The positions of several DNase I-hypersensitive (DH) sites have been mapped in the second and third introns of the human apolipoprotein B gene. Two such DH sites, I and V, are present both in human hepatoma (HepG2) and colon carcinoma (CaC…
Identification of a negative regulatory region 5' of the human apolipoprotein B promoter. Open
We have identified a negative regulatory region between positions -1802 and -3211 of the human apolipoprotein B gene that reduces expression of the gene. This "reducer" effect was detected in transient transfection experiments performed wi…
Characterization of tissue-specific enhancer elements in the second intron of the human apolipoprotein B gene. Open
We report the identification and characterization of tissue-specific transcriptional enhancer elements that influence the expression of the human apolipoprotein B gene. A 704-base pair PstI fragment comprising sequences from the first and …
Structure and functional expression of a cloned<i>Xenopus</i>thyroid hormone receptor Open
A clone corresponding to a thyroid hormone receptor was isolated from a Xenopus laevis cDNA library prepared from folliculated oocytes. The cDNA encodes a protein of 418 amino acid residues with a domain structure, including a putative DNA…