Abdul Rehman Khan
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Impact of CYP3A5 Gene Polymorphisms on Tacrolimus Pharmacokinetics and Renal Allograft Rejection in Kidney Transplant Recipients: A Meta-Analysis Across Ethnic Populations Open
Tacrolimus is a cornerstone immunosuppressant in kidney transplantation, but its pharmacokinetics show significant interindividual variability, primarily due to CYP3A5 polymorphisms. This meta-analysis evaluated the impact of CYP3A5 expres…
Comparative Relation of California Mastitis Test (CMT), Surf Field Mastitis Test (SFMT) and Modified Surf Field Mastitis Test (MSFMT) for Detection of Sub-Clinical Mastitis in Cattle and Buffaloes Open
This study demonstrated a comprehensive comparative evaluation of three mastitis detection tests: California Mastitis Test (CMT), Modified Surf Field Mastitis Test (MSFMT), and Surf Field Mastitis Test (SFMT) in 100 lactating animals (50 c…
View article: <b>THE GENETIC CURE FOR BLINDNESS: ADVANCES IN RETINAL THERAPY</b>
<b>THE GENETIC CURE FOR BLINDNESS: ADVANCES IN RETINAL THERAPY</b> Open
Background: Gene therapy involves the transfer of genetic material to specific tissues or organs to achieve therapeutic effects, aiming to correct genetic abnormalities or diseases. This method utilizes cells as biological vehicles to deli…
A multivariate analysis of seed priming agents and dosage on germination performance seedling growth and biochemical profiling in tomato Open
The seed sector and end users are encountering various problems, such as substandard and non-certified tomato seed production, which has resulted in reduced yield. Seed priming is a promising method to enhance germination, vigor, stress to…
Overview of the Vital Role of Vitamin D: Functions, Deficiency Syndromes, and Impact Throughout Life Open
The recent study provides a comprehensive overview of vitamin D, emphasizing its biological roles, sources, and health implications. Vitamin D, a fat-soluble prohormone, is essential for bone health, immune function, mental well-being, rep…
Investigating the role of Vitamin D and its targeted gene-pathway interactions involved in cardiometabolic health Open
Objectives Low levels of Vitamin D and its related gene variants are implicated in cardio-metabolic disorders (CMDs). This study aimed to elucidate the effect of Vitamin D deficiency and the relationship of genetic polymorphisms of Vitamin…
View article: Atmosclear (Ai-Ml De-Haze/De-Smoking Algorithm)
Atmosclear (Ai-Ml De-Haze/De-Smoking Algorithm) Open
Surveillance footage quality is often degraded by environmental factors like noise and fog, impacting monitoring accuracy. AtmosClear is an AI-ML solution designed to enhance video clarity in challenging conditions. It employs deep learnin…
View article: Channel Boosted CNN-Transformer-based Multi-Level and Multi-Scale Nuclei Segmentation
Channel Boosted CNN-Transformer-based Multi-Level and Multi-Scale Nuclei Segmentation Open
Accurate nuclei segmentation is an essential foundation for various applications in computational pathology, including cancer diagnosis and treatment planning. Even slight variations in nuclei representations can significantly impact these…
Particle Multi-Axis Transformer for Jet Tagging Open
Jet tagging is an essential categorization problem in high energy physics. In recent times, Deep Learning has not only risen to the challenge of jet tagging but also significantly improved its performance. In this article, we proposed an i…
Enhanced Efficacy of Homeophotodynamic Therapy of Rhobdomyosarcoma Cancer Cells by Using Chemo-Drug as an Adjuvant Agent Open
After cardiovascular diseases, the leading cause of death all around the world is cancer. Rhobdomyosarcoma (RMS) is the cancer of soft tissues and it mostly occurs in children and in adults aged between 10 and 25 years. There are several t…
E001 Pre-screen chest X-ray before starting methotrexate in autoimmune disease Open
Background/Aims This audit seeks to assess adherence to BSR guidelines and NICE recommendations concerning chest X-ray screening before initiating methotrexate. We also aim to evaluate the time elapsed from X-ray to radiologist reporting a…
Clinical characteristics and outcome of genitourinary tuberculosis in Balochistan: An observational study. Open
Objective: To make aware that the healthcare professionals should diagnose GUTB as early as possible to avoid the grave side effects of untreated cases as it can lead to the gross structural abnormalities in the Genito urinary system. Stud…
View article: Uniplanar External Fixator as a Definitive Treatment for Open Fracture of Tibia
Uniplanar External Fixator as a Definitive Treatment for Open Fracture of Tibia Open
Aim: Tibia is exposed to majority of trauma and accidents due to its location in the body. That’s why most of time it sustains open fracture in trauma and have high frequency of infected non union due to precarious blood supply. Definitive…
Determining epitope specificity of T-cell receptors with transformers Open
Summary T-cell receptors (TCRs) on T cells recognize and bind to epitopes presented by the major histocompatibility complex in case of an infection or cancer. However, the high diversity of TCRs, as well as their unique and complex binding…
Chest X-Ray Severity Index as a Predictor of Requiring Invasive Positive Pressure Ventilation in COVID-19 Positive Patients Open
The aim of this study is to see the role of the chest X-ray severity index (Brixia score) as a predictor of requiring invasive positive pressure ventilation in COVID-19-positive patients.This descriptive cross-sectional prospective study w…
AB129. SOH23ABS_101. The evaluation of compliance with iRefer guidelines for abdominal imaging and the discovery of new pathologic findings on the abdominal X-ray (AXR) performed Open
Background: Attendance of adult patients to the emergency department (ED) with acute abdominal pain is a frequent event. Abdominal X-ray (AXR) imaging is commonly the choice of investigation but previous studies have suggested that AXR pla…
AB130. SOH23ABS_102. Waiting times in the emergency department from triage to discharge or referral to another team Open
Background: Waiting times in Irish hospital have become a major issue in later times. It frequently appears on the news causing distress on the population. The focus on the blame is given to doctors. The purpose of this audit was to evalua…
Determining epitope specificity of T-cell receptors with transformers Open
Motivation T-cell receptors (TCR) on T cells recognize and bind to epitopes presented by the major histocompatibility complex (MHC) in case of an infection or cancer. However, the high diversity of TCRs, as well as their unique and complex…
Single Stage in Situ Suture Repair of a Multi-Ligament Knee Injury, an Observational Study Open
Objective: This study aims to observe the clinical outcomes associated with in situ single-stage suture repair for knee dislocation in patients suffering from multiple knee ligament injuries with the use of unabsorbable materials of the su…
View article: Antibacterial, Antioxidant and Physicochemical Properties of Pipper nigram Aided Copper Oxide Nanoparticles
Antibacterial, Antioxidant and Physicochemical Properties of Pipper nigram Aided Copper Oxide Nanoparticles Open
The Pipper nigram (P. nigram) leaf extract was used for the biosynthesis of copper oxide nanoparticles (CuO NPs) and the successful formation of the resultant product was confirmed through several physicochemical techniques. The chemical s…
Systemic analysis identifying <span>PVT1</span>/<span>DUSP13</span> axis for microvascular invasion in hepatocellular carcinoma Open
Background Microvascular invasion (MVI) is an independent detrimental risk factor for tumor recurrence and poor survival in hepatocellular carcinoma (HCC). Competitive endogenous RNA (ceRNA) networks play a pivotal role in the modulation o…
Docking Score Function uncovers Arbutin, Berginin and Paullinic Acid as Potential Natural Inhibitors of Human Peroxisome Proliferator-Activated Receptors Open
Peroxisome proliferator-activated receptor alpha (PPAR-alpha) is a key regulator of lipid homeostasis in hepatocytes and target for fatty acids and hypolipidemic drugs. Different natural molecules from two locally available plants Trillium…
Trade Facilitation and Agriculture Sector Performance in Sub-Saharan Africa: Insightful Policy Implications for Economic Sustainability Open
This study investigates the impact of trade facilitation though costs, documents, and time to import and export—on agricultural sector performance (ASP) for a panel of 33 Sub-Saharan African (SSA) countries from 2005 to 2019. The empirical…
Proteomics‐based identification of the role of osteosarcoma amplified‐9 in hepatocellular carcinoma recurrence Open
Hepatocellular carcinoma (HCC) is one of the most prevalent malignancies; its recurrence is associated with high mortality and poor recurrence‐free survival and is affected by multisystem and multilevel pathological changes. To identify th…
View article: Correlation between Salivary Levels of IGF-1, IGFBP-3, IGF-1/IGFBP3 Ratio with Skeletal Maturity Using Hand-Wrist Radiographs
Correlation between Salivary Levels of IGF-1, IGFBP-3, IGF-1/IGFBP3 Ratio with Skeletal Maturity Using Hand-Wrist Radiographs Open
Objective: The relevance of growth determination in orthodontics is driving the search for the most precise and least invasive way of tracking the pubertal growth spurt. Our aim was to explore whether minimally invasive salivary estimation…