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View article: Mpox animal models: a comprehensive evaluation of susceptible species for pathogenesis studies and drug discovery
Mpox animal models: a comprehensive evaluation of susceptible species for pathogenesis studies and drug discovery Open
Mpox, formerly known as monkeypox, has shifted from a regional concern to a global health priority. Progress toward targeted antivirals and vaccines, however, still hinges on a complex array of animal models developed over the last sixty y…
View article: Ebola-specific therapeutic antibodies from lab to clinic: The example of ZMapp
Ebola-specific therapeutic antibodies from lab to clinic: The example of ZMapp Open
In the 1990s, monoclonal antibodies (mAbs) progressed from scientific tools to advanced therapeutics, particularly for the treatment of cancers and autoimmune and inflammatory disorders. In the arena of infectious disease, the inauguration…
View article: Medically Significant Vector-Borne Viral Diseases in Iran
Medically Significant Vector-Borne Viral Diseases in Iran Open
Vector-borne viral diseases (VBVDs) continue to pose a considerable public health risk to animals and humans globally. Vectors have integral roles in autochthonous circulation and dissemination of VBVDs worldwide. The interplay of agricult…
View article: SARS-CoV-2 infection-induced immunity reduces rates of reinfection and hospitalization caused by the Delta or Omicron variants
SARS-CoV-2 infection-induced immunity reduces rates of reinfection and hospitalization caused by the Delta or Omicron variants Open
During a pandemic, effective vaccines are typically in short supply, particularly at onset intervals when the wave is accelerating. We conducted an observational, retrospective analysis of aggregated data from all patients who tested posit…
View article: Rhesus macaques show increased resistance to repeated SHIV intrarectal exposure following a heterologous regimen of rVSV vector vaccine expressing HIV antigen
Rhesus macaques show increased resistance to repeated SHIV intrarectal exposure following a heterologous regimen of rVSV vector vaccine expressing HIV antigen Open
Despite the human immunodeficiency virus (HIV) pandemic continuing worldwide for 40 years, no vaccine to combat the disease has been licenced for use in at risk populations. Here, we describe a novel recombinant vesicular stomatitis virus …