Arbind Dubey
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View article: Updates on controversies surrounding the staging and management of newly diagnosed localized prostate cancer using prostate-specific membrane antigen (PSMA) positron emission tomography
Updates on controversies surrounding the staging and management of newly diagnosed localized prostate cancer using prostate-specific membrane antigen (PSMA) positron emission tomography Open
There are controversies surrounding indications for prostate-specific membrane antigen (PSMA) positron-emission tomography (PET) and the subsequent management of localized disease. Conventional imaging is not a necessary prerequisite to PS…
View article: Moving towards single fraction peripheral lung stereotactic body radiation therapy: patient care during and after the global COVID-19 pandemic
Moving towards single fraction peripheral lung stereotactic body radiation therapy: patient care during and after the global COVID-19 pandemic Open
Aim/objectives: Single-fraction stereotactic body radiation therapy (SF-SBRT) for peripheral lung tumors was reviewed. Materials & methods: Medically inoperable peripheral lung tumors eligible for SF-SBRT 34 Gray were treated. Patient char…
View article: Hypofractionated Radiotherapy for Hematologic Malignancies during the COVID-19 Pandemic and Beyond
Hypofractionated Radiotherapy for Hematologic Malignancies during the COVID-19 Pandemic and Beyond Open
Purpose: Radiotherapy is integral in the management of hematological malignancies (HM). Standard radiotherapy dose fractionation regimens range between 20 and 50 Gy in 10–25 fractions over 2–5 weeks. This study presents the outcomes of pat…
View article: Hypofractionated Radiotherapy for Hematologic Malignancies during the COVID-19 Pandemic and Beyond
Hypofractionated Radiotherapy for Hematologic Malignancies during the COVID-19 Pandemic and Beyond Open
Purpose Radiotherapy is integral in the management of hematological malignancies (HM). Standard radiotherapy dose fractionation regimens range between 20-50 Gy in 10-25 fractions over 2-5 weeks. This study presents the outcomes of patients…
View article: Factors Associated with Long-Term Prostate Cancer Survival after Palliative Radiotherapy to a Bone Metastasis and Contemporary Palliative Systemic Therapy: A Retrospective, Population-Based Study
Factors Associated with Long-Term Prostate Cancer Survival after Palliative Radiotherapy to a Bone Metastasis and Contemporary Palliative Systemic Therapy: A Retrospective, Population-Based Study Open
Background: Radiation therapy (RT) is an established palliative treatment for bone metastases; however, little is known about post-radiation survival and factors which impact it. The aim of this study was to assess a population-based sampl…
View article: Do Sustainable Palliative Single Fraction Radiotherapy Practices Proliferate or Perish 2 Years after a Knowledge Translation Campaign?
Do Sustainable Palliative Single Fraction Radiotherapy Practices Proliferate or Perish 2 Years after a Knowledge Translation Campaign? Open
In early 2017, the Canadian Partnership Against Cancer and CancerCare Manitoba undertook a comprehensive knowledge translation (KT) campaign to improve the utilization of single fraction radiotherapy (SFRT) over multiple fraction radiother…
View article: A retrospective study on clinical factors influencing intra-fraction motion using volumetric imaging for spine stereotactic body radiotherapy.
A retrospective study on clinical factors influencing intra-fraction motion using volumetric imaging for spine stereotactic body radiotherapy. Open
The need for CBCT and imagining for positional errors is emphasized while treating with SBRT spine and the need for proper immobilization techniques.
View article: Gastrointestinal and genitourinary toxicity profiles of metformin versus placebo in men with prostate cancer receiving prostate radiotherapy: interim toxicity results of a double-blinded, multicenter, phase II randomized controlled trial
Gastrointestinal and genitourinary toxicity profiles of metformin versus placebo in men with prostate cancer receiving prostate radiotherapy: interim toxicity results of a double-blinded, multicenter, phase II randomized controlled trial Open
Androgen deprivation therapy (ADT) used for prostate cancer (PCa) management is associated with metabolic and anthropometric toxicity. Metformin given concurrent to ADT is hypothesized to counteract these changes. This planned interim anal…
View article: Do sustainable palliative single fraction radiotherapy practices proliferate or perish 2 years after a knowledge translation campaign?
Do sustainable palliative single fraction radiotherapy practices proliferate or perish 2 years after a knowledge translation campaign? Open
BACKGROUND There is a paucity of data regarding the time-dependent effects of knowledge translation (KT) campaign derived Radiation Oncologist (RO) prescription behaviour. In early 2017, the XXXX and XXXX undertook a comprehensive KT campa…
View article: The impact of timing of concurrent chemoradiation in limited stage SCLC undergoing platinum-based chemotherapy
The impact of timing of concurrent chemoradiation in limited stage SCLC undergoing platinum-based chemotherapy Open
Review question / Objective: Does the timing of concurrent chemoradiation in limited stage SCLC undergoing platinumbased chemotherapy affect outcomes.Rationale: Small cell lung cancer (SCLC) occurs in around 15% of all lung cancer cases.1T…
View article: Merkel Cell Carcinoma of the Head and Neck
Merkel Cell Carcinoma of the Head and Neck Open
Merkel cell carcinoma (MCC) of the head and neck is a rare and aggressive non-melanoma skin cancer. The objective of this study was to assess the oncological outcome of MCC by retrospective review of electronic and paper records of a popul…
View article: Gastrointestinal and Genitourinary Toxicity Profiles of Metformin Versus Placebo in Men With Prostate Cancer Receiving Pelvic Radiotherapy: Interim Toxicity Results of a Double-blinded, Multicenter, Phase II Randomized Controlled Trial
Gastrointestinal and Genitourinary Toxicity Profiles of Metformin Versus Placebo in Men With Prostate Cancer Receiving Pelvic Radiotherapy: Interim Toxicity Results of a Double-blinded, Multicenter, Phase II Randomized Controlled Trial Open
Androgen deprivation therapy (ADT) used for prostate cancer (PCa) management is associated with metabolic and anthropometric toxicity. Metformin given concurrent to ADT is hypothesized to counteract these changes. This planned interim anal…
View article: Additional file 1 of Gastrointestinal and genitourinary toxicity profiles of metformin versus placebo in men with prostate cancer receiving prostate radiotherapy: interim toxicity results of a double-blinded, multicenter, phase II randomized controlled trial
Additional file 1 of Gastrointestinal and genitourinary toxicity profiles of metformin versus placebo in men with prostate cancer receiving prostate radiotherapy: interim toxicity results of a double-blinded, multicenter, phase II randomized controlled trial Open
Additional file 1. Table S1: Gastrointestinal and genitourinary toxicities by treatment.
View article: A modern mold room: Meshing 3D surface scanning, digital design, and 3D printing with bolus fabrication
A modern mold room: Meshing 3D surface scanning, digital design, and 3D printing with bolus fabrication Open
Purpose This case series represents an initial experience with implementing 3‐dimensional (3D) surface scanning, digital design, and 3D printing for bolus fabrication for patients with complex surface anatomy where traditional approaches a…
View article: Clinical Characteristics and Prognosis of Primary Tracheal Cancer: A Single Institution Experience
Clinical Characteristics and Prognosis of Primary Tracheal Cancer: A Single Institution Experience Open
Background Primary tracheal cancers (PTCs) are rare and current evidence-based understanding is limited to retrospective reports and national databases. We present single institutional study of a historical cohort of PTC from Canadian prov…
View article: Low-cost optical scanner and 3-dimensional printing technology to create lead shielding for radiation therapy of facial skin cancer: First clinical case series
Low-cost optical scanner and 3-dimensional printing technology to create lead shielding for radiation therapy of facial skin cancer: First clinical case series Open
The scanner was found to be clinically acceptable, and we suggest that the use of an optical scanner and 3-dimensional printer technology become the new standard of care to generate lead shielding for orthovoltage radiation therapy of nonm…
View article: Emotional Turmoil in Oncology Patients
Emotional Turmoil in Oncology Patients Open
Emotional turmoil is a negative mental state involving feelings of panic, confusion and agitation.People experiencing emotional turmoil feel physically and mentally unwell which results in difficulty making decisions cancer diagnosis is ha…