Geethika Arekatla
YOU?
Author Swipe
View article: Alzheimer's disease and its co‐pathologies: Implications for hippocampal degeneration, cognitive decline, and the role of <i>APOE</i> ε4
Alzheimer's disease and its co‐pathologies: Implications for hippocampal degeneration, cognitive decline, and the role of <i>APOE</i> ε4 Open
INTRODUCTION In neurodegenerative dementias, the co‐occurrence and interaction of amyloid β peptide (Aβ), tau pathology, and other pathological lesions confound their individual contributions to neurodegeneration and their modulation by ri…
View article: Human Myelin Spheres for <i>In Vitro</i> Oligodendrocyte Maturation, Myelination and Neurological Disease Modeling
Human Myelin Spheres for <i>In Vitro</i> Oligodendrocyte Maturation, Myelination and Neurological Disease Modeling Open
Demyelinating diseases, such as multiple sclerosis, damage the protective myelin sheaths of the central nervous system. The development of effective therapies has been hampered by the lack of models that accurately replicate human myelin b…
View article: Alzheimer’s disease and its co-pathologies: implications for hippocampal degeneration, cognitive decline, and the role of <i>APOE</i> ε4
Alzheimer’s disease and its co-pathologies: implications for hippocampal degeneration, cognitive decline, and the role of <i>APOE</i> ε4 Open
INTRODUCTION In neurodegenerative dementias, the co-occurrence and interaction of Aβ, tau, and other pathological lesions confound their individual contributions to neurodegeneration and their modulation by risk factors. METHODS We analyze…
View article: Identification of an embryonic differentiation stage marked by Sox1 and FoxA2 co-expression using combined cell tracking and high dimensional protein imaging
Identification of an embryonic differentiation stage marked by Sox1 and FoxA2 co-expression using combined cell tracking and high dimensional protein imaging Open
Pluripotent mouse embryonic stem cells (ESCs) can differentiate to all germ layers and serve as an in vitro model of embryonic development. To better understand the differentiation paths traversed by ESCs committing to different lineages, …
View article: Optogenetic manipulation identifies the roles of ERK and AKT dynamics in controlling mouse embryonic stem cell exit from pluripotency
Optogenetic manipulation identifies the roles of ERK and AKT dynamics in controlling mouse embryonic stem cell exit from pluripotency Open
View article: Open-source personal pipetting robots with live-cell incubation and microscopy compatibility
Open-source personal pipetting robots with live-cell incubation and microscopy compatibility Open
Liquid handling robots have the potential to automate many procedures in life sciences. However, they are not in widespread use in academic settings, where funding, space and maintenance specialists are usually limiting. In addition, curre…
View article: Single cell biology—a Keystone Symposia report
Single cell biology—a Keystone Symposia report Open
Single cell biology has the potential to elucidate many critical biological processes and diseases, from development and regeneration to cancer. Single cell analyses are uncovering the molecular diversity of cells, revealing a clearer pict…
View article: Open-source personal pipetting robots with live-cell incubation and microscopy compatibility
Open-source personal pipetting robots with live-cell incubation and microscopy compatibility Open
Liquid handling robots have the potential to automate many procedures in life sciences. However, they are not in widespread use in academic settings, where funding, space and maintenance specialists are usually limiting. In addition, curre…
Priming exposures to lipopolysaccharides do not affect the induction of Polycomb target genes upon re-exposure Open
View article: IL10 Variant g.5311A Is Associated with Visceral Leishmaniasis in Indian Population
IL10 Variant g.5311A Is Associated with Visceral Leishmaniasis in Indian Population Open
Our analysis revealed four variations; rs1518111 (2195 A>G, intron), rs1554286 (2607 C>T, intron), rs3024496 (4976 T>C, 3' UTR) and rs3024498 (5311 A>G, 3' UTR). Of these, a variant g.5311A is significantly associated with VL (χ2=18.87; p …