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View article: Hypoxia-induced extracellular matrix changes are conserved in cancer and directly impact radiotherapy benefit
Hypoxia-induced extracellular matrix changes are conserved in cancer and directly impact radiotherapy benefit Open
Our overarching aim was to determine how hypoxia affects the extracellular matrix (ECM). Transcriptomic analysis (21,941 patients; 10 cancer types) identified ECM remodelling as the predominant pathway affected by hypoxia. Multi-omics conf…