Ari Mennander
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View article: Reply: How would a heterogeneous research population aid in interpreting study results?
Reply: How would a heterogeneous research population aid in interpreting study results? Open
View article: Severity of Ascending Aortic Degeneration in Patients With Chronic Obstructive Pulmonary Disease
Severity of Ascending Aortic Degeneration in Patients With Chronic Obstructive Pulmonary Disease Open
Background Ascending aortic dilatation is associated with increased susceptibility to aortic events. Chronic obstructive pulmonary disease (COPD) may add to tissue degeneration and inflammation associated with the risk of increased aortic …
View article: Complement expression in human atherosclerotic plaques and blood cells in patients with coronary artery disease
Complement expression in human atherosclerotic plaques and blood cells in patients with coronary artery disease Open
Background: Inflammatory processes are a key cause of atherosclerosis and cardiovascular diseases. Complement system has been implicated but evidence is less clear. We tested whether atherosclerosis severity, plaque types, and vascular reg…
View article: Diabetes Mellitus Is Associated with Distinctive Aortic Wall Degeneration During Acute Type A Aortic Dissection
Diabetes Mellitus Is Associated with Distinctive Aortic Wall Degeneration During Acute Type A Aortic Dissection Open
Background: Non-adjustable patient characteristics such as diabetes mellitus may influence surgical decision-making and outcome after acute type A aortic dissection (ATAAD). The aim of this study was to compare the degree of aortic wall at…
View article: Prevalence and risk factors of thoracic aortic dilatation detected incidentally in adjuvant radiotherapy planning CT scans in patients with breast cancer
Prevalence and risk factors of thoracic aortic dilatation detected incidentally in adjuvant radiotherapy planning CT scans in patients with breast cancer Open
Thoracic aortic dilatations (TADs) are commonly detected incidentally. A TAD may develop into aortic aneurysm and subsequently lead to aortic dissection, a highly lethal condition. Earlier detection of TADs could improve the surveillance a…
View article: Superficial Parasternal Intercostal Plane Block and Full Sternotomy; A Randomized Trial
Superficial Parasternal Intercostal Plane Block and Full Sternotomy; A Randomized Trial Open
Objectives Cardiac surgery via full sternotomy impacts postoperative lung function. We studied whether ultrasound-guided superficial parasternal intercostal plane block (SPIP) before surgical aortic valve replacement via full sternotomy wo…
View article: CMKLR-1 Expression in Human Aorta Is Dominated by Smooth Muscle Cell Positivity
CMKLR-1 Expression in Human Aorta Is Dominated by Smooth Muscle Cell Positivity Open
Chemokine-like receptor 1 (CMKLR-1) is a G-protein-coupled receptor that functions as the binding site of chemerin. It induces chemotaxis in various immune cells, and it has recently been linked to vascular remodeling in inflammation. In t…
View article: Increased angiogenesis and lymphangiogenesis in rheumatic mitral valves
Increased angiogenesis and lymphangiogenesis in rheumatic mitral valves Open
Acute rheumatic fever (ARF) and rheumatic heart disease (RHD) create a global burden in the field of cardiovascular medicine due to significant morbidity and mortality, particularly in low- and middle-income countries and the underprivileg…
View article: Cardiopulmonary Bypass Time During Surgery for Acute Type A Aortic Dissection and Mid-Term Survival
Cardiopulmonary Bypass Time During Surgery for Acute Type A Aortic Dissection and Mid-Term Survival Open
We evaluated the association between cardiopulmonary bypass (CPB) time during surgery for acute type A aortic dissection (ATAAD) and mid-term survival. Data of 1122 patients who underwent surgery for ATAAD in eight Nordic centers from Janu…
View article: Long-term risk for incident cancer in patients undergoing coronary artery bypass grafting with or without cardiopulmonary bypass: a nationwide population-based study
Long-term risk for incident cancer in patients undergoing coronary artery bypass grafting with or without cardiopulmonary bypass: a nationwide population-based study Open
OBJECTIVES It has been suggested that long-term risk for incident cancer is increased in patients operated with cardiopulmonary bypass. We compared the risk for incident cancer and cancer-specific death between patients undergoing coronary…
View article: Invited commentary to “The effect of diabetes on long-term outcomes in patients following coronary artery bypass grafting” (EJCTS-2024-100907)
Invited commentary to “The effect of diabetes on long-term outcomes in patients following coronary artery bypass grafting” (EJCTS-2024-100907) Open
View article: Prognostic analysis of acute type A aortic dissection after different surgical interventions: a cohort study
Prognostic analysis of acute type A aortic dissection after different surgical interventions: a cohort study Open
There was no significant difference in postoperative mortality between the Sun procedure group and the non-Sun procedure group. The incidence of spinal MPS in the Sun procedure group was higher than that in the non-Sun procedure group, whi…
View article: Interplay of atherosclerosis and medial degeneration in human ascending aorta
Interplay of atherosclerosis and medial degeneration in human ascending aorta Open
The previous understanding has been that atherosclerosis tends to increase distally from the ascending aorta, but recent studies and practical experience have indicated that atherosclerosis occurs in the ascending aorta more than previousl…
View article: Cardiac surgery and long-term risk for incident cancer: A nationwide population-based study
Cardiac surgery and long-term risk for incident cancer: A nationwide population-based study Open
Patients who underwent cardiac surgery have lower risk for cancer and cancer-specific mortality than matched control subjects.
View article: Bleeding is associated with severely impaired outcomes in surgery for acute type a aortic dissection
Bleeding is associated with severely impaired outcomes in surgery for acute type a aortic dissection Open
Background. Surgery for acute type A aortic dissection confers a risk for significant bleeding. We analyzed the impact of massive bleeding on complications after surgery for acute type A aortic dissection. Methods. Patients u…
View article: Early Graft Reperfusion and Arrhythmias After Coronary Artery Bypass Grafting
Early Graft Reperfusion and Arrhythmias After Coronary Artery Bypass Grafting Open
Background Arrhythmia after coronary artery bypass grafting (CABG) may occur immediately after the abrupt onset of reperfusion via all coronary bypass grafts simultaneously. We investigated whether early reperfusion of the left anterior de…
View article: The proximal extension of acute type A aortic dissection is associated with ascending aortic wall degeneration
The proximal extension of acute type A aortic dissection is associated with ascending aortic wall degeneration Open
Histopathology of the ascending aorta during ATAAD reveals distinctive aortic wall degeneration in patients with aortic root involvement vs. not. The degree of mucoid extracellular matrix accumulation assessed postoperatively is ass…
View article: Antithrombotic management after aortic valve replacement with biological prosthesis: a meta-analysis
Antithrombotic management after aortic valve replacement with biological prosthesis: a meta-analysis Open
Background We aimed to summarise the existing knowledge regarding antithrombotic medications following surgical aortic valve replacement (SAVR) using a biological valve prosthesis. Methods We performed a meta-analysis of studies that repor…
View article: The autonomic nerves around the vein of Marshall: a postmortem study with clinical implications
The autonomic nerves around the vein of Marshall: a postmortem study with clinical implications Open
This study aims to analyze the vein of Marshall (VOM) in human autopsy hearts and its correlation with clinical data to elucidate the morphological substrates of atrial fibrillation (AF) and other cardiac diseases. Twenty‐three adult autop…
View article: Aortic elastic fiber degeneration during acute type a aortic dissection and reverse aortic remodeling
Aortic elastic fiber degeneration during acute type a aortic dissection and reverse aortic remodeling Open
View article: Histopathology reveals concealed aortic valve inflammation
Histopathology reveals concealed aortic valve inflammation Open
View article: Detailed study of collagen, vasculature, and innervation in the human cardiac conduction system
Detailed study of collagen, vasculature, and innervation in the human cardiac conduction system Open
Our results provide new insights into the unique morphology of the human CCS collagen, fat, vasculature, and innervation. A deeper understanding of the CCS anatomical components and morphologic substrates' role will help in elucidating the…
View article: Rapid-deployment aortic valve replacement during challenging aortic valve reoperation: a case report
Rapid-deployment aortic valve replacement during challenging aortic valve reoperation: a case report Open
A previously implanted stenotic aortic valve bioprosthesis with stenotic coronary ostia and intramyocardial calcium was surgically debrided resulting in disruption of the left outflow track. A rapid-deployment aortic valve bioprosthesis wa…
View article: Impact of national holidays and weekends on incidence of acute type A aortic dissection repair
Impact of national holidays and weekends on incidence of acute type A aortic dissection repair Open
View article: Temperature effects on incidence of surgery for acute type A aortic dissection in the Nordics
Temperature effects on incidence of surgery for acute type A aortic dissection in the Nordics Open
We aimed to investigate a hypothesised association between daily mean temperature and the risk of surgery for acute type A aortic dissection (ATAAD). For the period of 1 January 2005 until 31 December 2019, we collected daily data on mean …
View article: Myocardial interaction of apixaban after experimental acute volume overload
Myocardial interaction of apixaban after experimental acute volume overload Open
Objective Acute volume overload (AVO) induces early ischemia-like changes in intramyocardial arteries. We investigated whether the Factor Xa (FXa) inhibitor apixaban interacts with the myocardium early after AVO. Methods Fifty-five syngene…
View article: Human Pulmonary Vein Myocardial Sleeve Autonomic Neural Density and Cardiovascular Mortality
Human Pulmonary Vein Myocardial Sleeve Autonomic Neural Density and Cardiovascular Mortality Open
Myocardial sleeves around pulmonary veins (PVs) are highly innervated structures with heterogeneous morphological and electrophysiological characteristics. Autonomic nerve dysfunction in the myocardium may be associated with an increased r…
View article: Is mood associated with perception of recovery? Preoperative depression versus postoperative delirium after cardiac surgery
Is mood associated with perception of recovery? Preoperative depression versus postoperative delirium after cardiac surgery Open
The author alone is responsible for the Invited Commentary, which does not necessarily reflect the policy of the Journal.
View article: Ascending aortic wall degeneration in patients with bicuspid versus tricuspid aortic valve
Ascending aortic wall degeneration in patients with bicuspid versus tricuspid aortic valve Open
Background The magnitude of ascending aortic degeneration in patients with bicuspid aortic valves (BAV) is controversial. Methods The aim of this study was to investigate ascending aortic wall degeneration in patients with BAV as compared …
View article: Autonomic nerves in myocardial sleeves around caval veins: Potential role in cardiovascular mortality?
Autonomic nerves in myocardial sleeves around caval veins: Potential role in cardiovascular mortality? Open
Decrease of superior vena cava myocardial sleeve sympathetic nerves may be associated with cardiovascular mortality and/or aging. No difference in autonomic innervation was found between subjects with documented atrial fibrillation vs. sin…