Arianna Dal Buono
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View article: Variability and performance of radiologic stricture parameters in Crohn's disease: a systematic review and meta-analysis
Variability and performance of radiologic stricture parameters in Crohn's disease: a systematic review and meta-analysis Open
View article: Digital biomarkers and artificial intelligence: a new frontier in personalized management of inflammatory bowel disease
Digital biomarkers and artificial intelligence: a new frontier in personalized management of inflammatory bowel disease Open
Background and aims Artificial intelligence (AI) is rapidly gaining traction in gastroenterology, particularly in the management of inflammatory bowel disease (IBD). Given the complexity of IBD care, AI offers the potential to enhance diag…
View article: GLP-1 receptor agonists in IBD: exploring the crossroads of metabolism and inflammation
GLP-1 receptor agonists in IBD: exploring the crossroads of metabolism and inflammation Open
Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) represent a cornerstone in the treatment of diabetes and obesity and have emerged as a promising option for other metabolic disorders, including hepatic steatosis. Recent evidence highl…
View article: Navigating Neoplasm Risk in Inflammatory Bowel Disease and Primary Sclerosing Cholangitis
Navigating Neoplasm Risk in Inflammatory Bowel Disease and Primary Sclerosing Cholangitis Open
(1) Background and Aims: Patients with inflammatory bowel disease (IBD) and primary sclerosing cholangitis (PSC) face a significantly increased risk of malignancies, including a 10-fold higher risk for colorectal cancer (CRC) and a lifetim…
View article: Collecting and Analyzing IBD Clinical Data for Machine-Learning: Insights from an Italian Cohort
Collecting and Analyzing IBD Clinical Data for Machine-Learning: Insights from an Italian Cohort Open
Research of Inflammatory Bowel Disease (IBD) involves integrating diverse and heterogeneous data sources, from clinical records to imaging and laboratory results, which presents significant challenges in data harmonization and exploration.…
View article: Therapeutic adherence in inflammatory bowel disease: User guide from a multidisciplinary modified Delphi consensus
Therapeutic adherence in inflammatory bowel disease: User guide from a multidisciplinary modified Delphi consensus Open
View article: TL1A as a Target in Inflammatory Bowel Disease: Exploring Mechanisms and Therapeutic Potential
TL1A as a Target in Inflammatory Bowel Disease: Exploring Mechanisms and Therapeutic Potential Open
Inflammatory bowel diseases (IBD) are chronic disorders characterized by persistent inflammation of the gastrointestinal tract. Despite advances in treatment, a significant proportion of patients remain refractory to current therapies and …
View article: Drug Development in Inflammatory Bowel Diseases: What Is Next?
Drug Development in Inflammatory Bowel Diseases: What Is Next? Open
Background/Objectives: Inflammatory bowel diseases (IBDs), which include Crohn’s disease (CD) and ulcerative colitis (UC), are chronic conditions requiring long-term therapy to maintain remission and improve quality of life. Despite the ap…
View article: Collagen Paste Injection in Crohn's Disease Perianal Fistula: Long-term Outcomes of a Pilot, Prospective Cohort Study
Collagen Paste Injection in Crohn's Disease Perianal Fistula: Long-term Outcomes of a Pilot, Prospective Cohort Study Open
The results suggest that collagen paste injection may represent a safe and effective option for Crohn's perianal fistulas, worth further investigation in larger trials.
View article: Hereditary Colorectal Cancer Syndromes and Inflammatory Bowel Diseases: Risk Management and Surveillance Strategies
Hereditary Colorectal Cancer Syndromes and Inflammatory Bowel Diseases: Risk Management and Surveillance Strategies Open
Background and aims: Hereditary colorectal cancer syndromes (HCCS), including familial adenomatous polyposis (FAP) and Lynch syndrome (LS), are the two most important high-risk conditions for colorectal cancer (CRC). Inflammatory bowel dis…
View article: Eosinophils, Eosinophilic Gastrointestinal Diseases, and Inflammatory Bowel Disease: A Critical Review
Eosinophils, Eosinophilic Gastrointestinal Diseases, and Inflammatory Bowel Disease: A Critical Review Open
Background/Objectives: Inflammatory bowel disease (IBD) and eosinophilic gastrointestinal diseases (EGIDs) are complex, multifactorial chronic inflammatory disorders affecting the gastrointestinal tract. Their epidemiology, particularly fo…
View article: An international multicentre study of <scp>SwiTching</scp> from Intravenous to subcutaneous <scp>inflixiMab</scp> and <scp>vEdolizumab</scp> in inflammatory bowel diseases: The <scp>TIME</scp> study
An international multicentre study of <span>SwiTching</span> from Intravenous to subcutaneous <span>inflixiMab</span> and <span>vEdolizumab</span> in inflammatory bowel diseases: The <span>TIME</span> study Open
Background and Aims Subcutaneous (SC) formulations of infliximab (IFX) and vedolizumab (VDZ) are approved for the treatment of inflammatory bowel diseases (IBDs). Our aim was to evaluate the effectiveness of switching from intravenous (IV)…
View article: Reporting of Magnetic Resonance Enterography in Inflammatory Bowel Disease: Results of an Italian Survey
Reporting of Magnetic Resonance Enterography in Inflammatory Bowel Disease: Results of an Italian Survey Open
Background/Objectives: Inflammatory bowel diseases (IBDs) are chronic disorders that require close monitoring with imaging techniques such as magnetic resonance enterography (MRE). Standardization of radiological reports is crucial for the…
View article: A 1-year follow-up study on checkpoint inhibitor-induced colitis: results from a European consortium
A 1-year follow-up study on checkpoint inhibitor-induced colitis: results from a European consortium Open
View article: 129P Clinical and molecular landscape of deficient mismatch repair (dMMR) colon cancer (CC) patients: Data from a large consecutive single-center cohort
129P Clinical and molecular landscape of deficient mismatch repair (dMMR) colon cancer (CC) patients: Data from a large consecutive single-center cohort Open
View article: Management of Post-Operative Crohn’s Disease: Knowns and Unknowns
Management of Post-Operative Crohn’s Disease: Knowns and Unknowns Open
Crohn’s disease (CD) is a chronic inflammatory disorder of the gastrointestinal tract characterized by relapsing–remission phases. CD often requires surgical intervention during its course, mainly ileo-cecal/ileo-colonic resection. However…
View article: Lynch Syndrome: From Multidisciplinary Management to Precision Prevention
Lynch Syndrome: From Multidisciplinary Management to Precision Prevention Open
Background and Aims: Lynch syndrome (LS) is currently one of the most prevalent hereditary cancer conditions, accounting for 3% of all colorectal cancers and for up to 15% of those with DNA mismatch repair (MMR) deficiency, and it was one …
View article: The gut-brain axis: Correlation of choroid plexus volume and permeability with inflammatory biomarkers in Crohn's disease
The gut-brain axis: Correlation of choroid plexus volume and permeability with inflammatory biomarkers in Crohn's disease Open
Inflammatory activity in patients with CD is associated with changes in CP volume and permeability, thus supporting the hypothesis that intestinal inflammation could affect the brain through the modulation of CP vascular barrier also in hu…
View article: Ophthalmological Manifestations in Inflammatory Bowel Diseases: Keep an Eye on It
Ophthalmological Manifestations in Inflammatory Bowel Diseases: Keep an Eye on It Open
Background and aims: Inflammatory bowel diseases (IBD) are multifactorial chronic inflammatory disorders affecting the gastrointestinal tract. However, a broad spectrum of extraintestinal manifestations (EIMs) is associated with IBD, affec…
View article: P079 Low-intensity Pulsed Ultrasound reflects the status of mucosal injury and repair through stage-specific miRNAs in experimental model of Ulcerative Colitis
P079 Low-intensity Pulsed Ultrasound reflects the status of mucosal injury and repair through stage-specific miRNAs in experimental model of Ulcerative Colitis Open
Background Diagnosis and therapeutic efficacy monitoring of Ulcerative Colitis (UC) are based on a multidisciplinary approach comprising symptomatology and invasive endoscopic assessment coupled to the histopathological characterization of…
View article: Clinical and Molecular Landscape of Mismatch Repair Deficient (Dmmr) Colon Cancer (Cc) Patients: Data from a Large Consecutive Single-Center Cohort
Clinical and Molecular Landscape of Mismatch Repair Deficient (Dmmr) Colon Cancer (Cc) Patients: Data from a Large Consecutive Single-Center Cohort Open
View article: Clinical and Molecular Landscape of Mismatch Repair Deficient (Dmmr) Colon Cancer (Cc) Patients: Data from a Large Consecutive Single-Center Cohort
Clinical and Molecular Landscape of Mismatch Repair Deficient (Dmmr) Colon Cancer (Cc) Patients: Data from a Large Consecutive Single-Center Cohort Open
View article: Psoriasis and inflammatory bowel disease: concomitant IMID or paradoxical therapeutic effect? A scoping review on anti-IL-12/23 and anti-IL-23 antibodies
Psoriasis and inflammatory bowel disease: concomitant IMID or paradoxical therapeutic effect? A scoping review on anti-IL-12/23 and anti-IL-23 antibodies Open
Inflammatory bowel diseases (IBD) and psoriasis are chronic inflammatory conditions belonging to the heterogeneous group of immune-mediated inflammatory diseases (IMIDs). A significant bidirectional link between these two entities has been…
View article: DOP88 Lipids drive myofibroblast activation and the epithelial-mesenchymal transition process in Crohn’s Disease
DOP88 Lipids drive myofibroblast activation and the epithelial-mesenchymal transition process in Crohn’s Disease Open
Background Fibrostenosis represents one of the major clinical complications of Crohn’s Disease (CD). However, the molecular mechanisms underlying intestinal fibrogenesis remain poorly understood and anti-fibrotic therapy has not yet been d…
View article: Treat-to-Target and Regular Surveillance of Inflammatory Bowel Disease Are Associated with Low Incidence and Early-Stage Detection of Malignancies: A Retrospective Cohort Study
Treat-to-Target and Regular Surveillance of Inflammatory Bowel Disease Are Associated with Low Incidence and Early-Stage Detection of Malignancies: A Retrospective Cohort Study Open
Inflammatory bowel diseases (IBD), including ulcerative colitis (UC) and Crohn’s disease (CD), increase the risk of malignancies, particularly colorectal cancer (CRC). We aimed to assess the incidence of malignancies in IBD patients manage…
View article: Leaving behind the Mucosa: Advances and Future Directions of Intestinal Ultrasound in Ulcerative Colitis
Leaving behind the Mucosa: Advances and Future Directions of Intestinal Ultrasound in Ulcerative Colitis Open
Inflammatory Bowel Diseases (IBD), mainly Ulcerative Colitis (UC) and Crohn’s Disease (CD), are disorders characterized by chronic inflammation with severe morbidity and long-term disabling quality of life outcomes. UC mainly affects the m…
View article: Dataset related to article "Prevalence of Germline Mutations in Cancer Predisposition Genes in Patients with Pancreatic Cancer or Suspected Related Hereditary Syndromes: Historical Prospective Analysis"
Dataset related to article "Prevalence of Germline Mutations in Cancer Predisposition Genes in Patients with Pancreatic Cancer or Suspected Related Hereditary Syndromes: Historical Prospective Analysis" Open
<p>This record contains raw data related to article "Prevalence of Germline Mutations in Cancer Predisposition Genes in Patients with Pancreatic Cancer or Suspected Related Hereditary Syndromes: Historical Prospective Analysis"</p…
View article: Lung Involvement in Inflammatory Bowel Diseases: Shared Pathways and Unwanted Connections
Lung Involvement in Inflammatory Bowel Diseases: Shared Pathways and Unwanted Connections Open
Inflammatory bowel diseases (IBDs) are chronic, relapsing inflammatory disorders of the gastrointestinal tract, frequently associated with extraintestinal manifestations (EIMs) that can severely affect IBD patients’ quality of life, someti…
View article: Checkpoint Inhibitor-Induced Colitis: From Pathogenesis to Management
Checkpoint Inhibitor-Induced Colitis: From Pathogenesis to Management Open
The advent of immunotherapy, specifically of immune checkpoint inhibitors (ICIs), for the treatment of solid tumors has deeply transformed therapeutic algorithms in medical oncology. Approximately one-third of patients treated with ICIs ma…
View article: Corrigendum to “Canonical and uncanonical pathogenic germline variants in colorectal cancer patients by next-generation sequencing in a European referral center”
Corrigendum to “Canonical and uncanonical pathogenic germline variants in colorectal cancer patients by next-generation sequencing in a European referral center” Open
The authors regret that in the original publication the affiliation addresses of Dr Poliani and Professor Malesci were incorrect. The correct affiliations are now given above. The authors would like to apologise for any inconvenience cause…